scholarly journals A Rare Case of Metastatic Mucinous Breast Carcinoma as a First Presentation of Colon Cancer in a Male Patient: Case Report and Review of the Literature

2020 ◽  
pp. 1-5
Author(s):  
Zaid Al-Ishaq ◽  
Zaid Al-Ishaq ◽  
Meghna Roy ◽  
B Bickley ◽  
A Bhatnagar ◽  
...  

The majority of breast tumors are primary; however metastatic tumor to the breast from extramammary sites has an incidence of 0.5 to 3% and can be misinterpreted clinically as a primary breast tumor. We report a case of metastatic mucinous breast carcinoma as a first presentation from colon cancer in a male patient who hasn’t had any bowel symptoms. The immunohistochemical study helped in suspecting the diagnosis, which was then confirmed by CT scan abdomen and pelvis and endoscopic biopsy of the colonic lesion. Management of such patients usually by palliative chemotherapy due to the aggressive nature of the disease however, surgical intervention may be indicated in symptomatic patient or risk of tumor ulceration as in our patient.

2010 ◽  
Vol 76 (8) ◽  
pp. 146-146
Author(s):  
Neyran Kertmen ◽  
Erkan Dogan ◽  
Kadri Altundag

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Hiromi Nagata ◽  
Hironori Tsujimoto ◽  
Yoshihisa Yaguchi ◽  
Keita Kouzu ◽  
Yujiro Itazaki ◽  
...  

Abstract Background Trastuzumab (T-mab)-based chemotherapy is a standard regimen for human epithelial growth factor 2 (HER2)-positive gastric cancer. However, some patients have demonstrated a change in HER2 status after T-mab-based treatment of breast cancer. We report a rare case of mixed adenoneuroendocrine carcinoma with loss of HER2 positivity after T-mab-based chemotherapy for HER2-positive gastric cancer. Case presentation A 60-year-old man presented with a mass of the upper abdomen, which was diagnosed as adenocarcinoma with a HER2 score of 3+ by endoscopic biopsy. He received seven cycles of combination chemotherapy with capecitabine, cisplatin, and T-mab. Subsequently, he underwent open total gastrectomy, distal pancreatosplenectomy, and extended left hepatic lobectomy as a conversion surgery. The surgically resected specimen demonstrated both adenocarcinoma and neuroendocrine components; therefore, it was diagnosed as HER2-negative mixed adenoneuroendocrine carcinoma. Although the patient received additional chemotherapy, multiple liver metastases appeared at 3 months postoperatively and he died at 6 months postoperatively because of the rapidly progressing metastatic tumor. Conclusions We encountered a rare case of rapidly progressive mixed adenoneuroendocrine carcinoma that was negative for HER2 expression after T-mab treatment combined with chemotherapy.


2018 ◽  
Vol 53 ◽  
pp. 58-60
Author(s):  
Irean Garcia-Hernandez ◽  
Carlos A. Lopez-Garcia ◽  
Servando Cardona-Huerta ◽  
Rocio Ortiz-Lopez ◽  
Nydia Paulina Herrera-Rios ◽  
...  

Cytopathology ◽  
2018 ◽  
Vol 30 (1) ◽  
pp. 128-130 ◽  
Author(s):  
Radhika Agarwal ◽  
Deepika Rana ◽  
Latika Gupta ◽  
Meeta Singh ◽  
Shyama Jain ◽  
...  

2016 ◽  
Vol 2016 (11) ◽  
pp. rjw193 ◽  
Author(s):  
Daniel Ching ◽  
Giles Davies

2018 ◽  
Vol 69 (2) ◽  
pp. 185-188 ◽  
Author(s):  
Simona Stolnicu ◽  
Alexandra Giurgi ◽  
Orsolya Bauer ◽  
Anca Chiriac ◽  
Cristian Podoleanu ◽  
...  

2018 ◽  
Vol 39 (11) ◽  
pp. 1033-1038 ◽  
Author(s):  
Tomoyuki Fujioka ◽  
Kazunori Kubota ◽  
Yuka Kikuchi ◽  
Junichi Tsuchiya ◽  
Ukihide Tateishi ◽  
...  

2012 ◽  
Vol 48 ◽  
pp. S89
Author(s):  
N. Tsoukalas ◽  
N. Apostolikas ◽  
M. Tolia ◽  
A. Papakostidi ◽  
G. Lypas ◽  
...  

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