Orphan designation: 9-cis, 12-cis-11,11-D2-linoleic acid ethyl ester, Treatment of infantile neuroaxonal dystrophy

2019 ◽  
Author(s):  
JIMD Reports ◽  
2020 ◽  
Vol 54 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Darius Adams ◽  
Mark Midei ◽  
Jahannaz Dastgir ◽  
Christina Flora ◽  
Robert J Molinari ◽  
...  

2020 ◽  
Vol 109 (11) ◽  
pp. 3496-3503
Author(s):  
J. Thomas Brenna ◽  
Genevieve James ◽  
Mark Midei ◽  
Frederic Heerinckx ◽  
Paldeep Atwal ◽  
...  

1988 ◽  
Vol 66 (5) ◽  
pp. 1283-1287 ◽  
Author(s):  
Santos Otin ◽  
Ignacio Senar ◽  
Ma José Soriano ◽  
Celso Gutierrez Losa

Excess molar enthalpies [Formula: see text] at 310.15 K and 101.32 kPa, have been determined for the binary mixtures: lauric acid ethyl ester +, stearic acid ethyl ester +, oleic acid ethyl ester +, linoleic acid ethyl ester + n-hexadecane, + toluene, or + ethyl alcohol, and elaidic acid ethyl ester + n-hexadecane or + toluene.The results show that HE of ester + n-hexadecane mixtures increases with decreasing chain length and with increasing unsaturation of the ester molecule. Ester + toluene mixtures are slightly exothermic and ester + alcohol are strongly endothermic, with [Formula: see text] values ranging from 1535 to 1740 J mol−1 at the maximum.


2014 ◽  
Vol 881-883 ◽  
pp. 419-422
Author(s):  
Ai Mei Yang ◽  
Yun Men ◽  
Han Han ◽  
Lin Yang ◽  
Xiao Long Shi ◽  
...  

Eight compounds were isolated from the ethanol extract of G. algida Pall. the structure of these compounds were identified as: oleic acid (1), linoleic acid (2), octacosanoic acid (3), β-sitosterol (4), 2,3-dihydroxybenzoic acid ethyl ester (5), n-butyl isobutyl phthalate (6), daucosterol (7), 5,8-dimethoxy furocoumarin (8). These structures were identified by NMR MS IR and other spectroscopic techniques. These compounds were isolated from this plant for the first time.


2014 ◽  
Vol 14 ◽  
pp. 71-74
Author(s):  
U Jargalsaikhan ◽  
S Javzan ◽  
D Selenge ◽  
D Nedelcheva ◽  
S Philipov ◽  
...  

n-Hexane and chloroform fractions of aerial parts and roots of Cicuta virosa L. were investigated by GC-MS. As a result of the study 25 fatty acids and their esters have been identified. Two unsaturated esters such as linoleic acid ethyl ester (IX, 16.66%), and n- hexadecanoic acid ethyl ester (VII, 10.12%), the fatty acid n-hexadecanioc acid (VI, 8.10%) made up the bulk of the aerial parts. Four unsaturated esters such as linoleic acid ethyl ester (IX, 10.15%), dibutylphthalate (XII, 9.55%), n-hexadecanoic acid ethyl ester (VII, 8.19%) and 9, 12, 15 - octadecatrienoic acid ethyl ester (X, 5.9%), two fatty acids as n-hexadecanoic acid (VI, 8,15%) and 9,12-octadecadienoic acid (VIII, 4,5%) predominated in the roots of Cicuta virosa L. These known fatty acids and their esters were found for the first time in this plant species. DOI: http://dx.doi.org/10.5564/mjc.v14i0.203 Mongolian Journal of Chemistry 14 (40), 2013, p71-74


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