The Effect of Pharmaceutical Grade L-glutamine (Endari) on Glycemic Control in Patients With Diabetes Mellitus Type II

2019 ◽  
Author(s):  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

scholarly journals Microalbuminuria and its association with glycemic control in patients with diabetes mellitus type II.

2020 ◽  
Vol 27 (08) ◽  
pp. 1617-1620
Author(s):  
Shahzad Ali Jiskani ◽  
Dolat Singh ◽  
Kumayl Abbas Meghji ◽  
Rizwan Ali Talpur ◽  
Jahanzaib Khan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Glycated Hemoglobin ◽  
Urinary Albumin ◽  
Diabetes Mellitus Type ◽  
P Value ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Group I ◽  
Patients With Diabetes

Diabetes mellitus is chronic condition with defect in regulation of insulin. Microalbuminuria is one of the early appearing markers of overt diabetic nephropathy. Uncontrolled glycemic status has been postulated to be associated with increase urinary albumin levels. Objectives: To find out the association of increased urinary albumin with poor glyemic status of patients with diabetes mellitus type II. Study Design: Cross Sectional study. Setting: Department of Pathology, Indus Medical College Hospital Tando Muhammad Khan. Period: November 2018 to June 2019. Material & Methods: Patients were divided into two groups: Group I (Poor glycemic control, HbA1c >7%) and Group II (Good glycemic control, HbA1c <7%). Glycated hemoglobin and microalbuminuria were evaluated in all patients. Data was analyzed using SPSS 21.0. P – value of <0.05 was considered as statistically significant. Results: Total of 213 patients were included in the study with male ratio (56.8%) slightly higher than females (43.19%). Mean age of patients was 42.3 ± 2.1 years. Mean glycated hemoglobin in Group I and II was 8.12 ± 0.97% and 5.98 ± 0.41% respectively. In Group I, 57.54% patients were detected with microalbuminuria as compared to Group II (12.26%). P value was statistically significant (<0.001). Conclusion: Microalbuminuria was found more frequently in patients with poor glycemic control. Early detection of urinary microalbumin in these patients may decrease the risk of kidney damage and appropriate and adequate management in initial stage.

scholarly journals PECULIARITIES OF STATE OF PROTECTION AND AGGRESSION FACTORS IN PATIENTS WITH DIABETES MELLITUS TYPE II AND GASTROESOPHAGEAL REFLUX DISEASE

2020 ◽  
Vol 1 ◽  
pp. 27-34 ◽  
Author(s):  
Aleksey Oparin ◽  
Anton Kudriavtsev ◽  
Anatoliy Oparin
Keyword(s):  
Diabetes Mellitus ◽  
Blood Flow ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Blood Flow Velocity ◽  
Reflux Disease ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

Diabetes mellitus is one of the most serious problems of the clinical medicine. This is determined by the fact that it is followed by multisystemic affects, as well as complications on the side of other organs and systems, among which a special place is occupied by gastroesophageal reflux disease. As for the combination and mutual influence of diabetes mellitus and gastroesophageal reflux disease, this issue has not been studied yet, the data of modern literature are not complete and quite contradictory. The aim of the study: to investigate the state of the factors of aggression and protection of the oesophageal mucosa in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease without associated pathology. Method. There were two groups of patients under observation. The first group included 45 patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease (26 men and 19 women). The second group included 38 patients with gastroesophageal reflux disease without associated pathology – 20 men and 18 women. By sex, age, body weight, Helicobacter pylori infection, smoking and alcohol consumption, both groups were comparable. The surveillance program included determining the compensation ratio of carbohydrate metabolism and the state of the factor. The antioxidant protection factor was assessed by the level of catalase activity in the blood serum, as well as by the diameter of the celiac trunk and the blood flow velocity in it. Statistical processing of the obtained data was carried out with the aid of the program WINDOWS STATISTIKA 6.0. For all types of analysis, differences were considered statistically significant with p<0.05. Results. During the study, we found that in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease, as well as in patients with gastroesophageal reflux disease without associated pathology, the level of pH-metry was reduced, but with varying measures of confidence. At the same time, we found that patients with GERD without associated pathology had a decrease in the blood flow velocity in the celiac trunk. Concurrently, we ascertained that the decrease in the blood flow velocity in patients of both groups reduced the diameter of the celiac trunk. Conclusions. In patients with diabetes mellitus type II, concomitant gastroesophageal reflux disease has a subtle clinical presentation that is affected by a significant decline in mucosal sealing protection factors. In patients with GERD without associated pathology, typical clinical manifestations, accompanied by inflammation, acid regurgitation and dyspepsia, are more vivid.

PREVALENCE OF DIABETIC NEUROPATHY IN PATIENTS WITH DIABETES MELLITUS TYPE II

2011 ◽  
Vol 22 ◽  
pp. S29
Author(s):  
Triada Exiara ◽  
Apostolos Konstantis ◽  
Maria Kouroupi ◽  
Anastasia Georgoulidou ◽  
Dimitra Papadopoulou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Neuropathy ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

scholarly journals Protein spectrum of blood plasma in patients with diabetes mellitus type II

2018 ◽  
Vol 3 (2) ◽  
pp. 95-105
Author(s):  
V. Ionova ◽  
V. Lantsova ◽  
E. Tkach ◽  
R. Ziganshin ◽  
V. Shender ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Plasma ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Protein Spectrum ◽  
Patients With Diabetes
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