REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients

2020 ◽  
Author(s):  
Keyword(s):  
Adult Patients ◽  
Eye Drops ◽  
Neurotrophic Keratitis

Treatment of patients with neurotrophic keratitis stages 2 and 3 with plasma rich in growth factors (PRGF-Endoret) eye-drops

2017 ◽  
Vol 38 (3) ◽  
pp. 1193-1204 ◽  
Author(s):  
Ronald Mauricio Sanchez-Avila ◽  
Jesus Merayo-Lloves ◽  
Ana Cristina Riestra ◽  
Luis Fernandez-Vega Cueto ◽  
Eduardo Anitua ◽  
...  
Keyword(s):  
Growth Factors ◽  
Eye Drops ◽  
Neurotrophic Keratitis

scholarly journals Maxillary Zoster and Neurotrophic Keratitis following Trigeminal Block

2019 ◽  
Vol 10 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Yang Kyung Cho ◽  
JinWoo Kwon ◽  
Sangeetha Pugazhendhi ◽  
Balamurali K. Ambati
Keyword(s):  
Herpes Zoster ◽  
Trigeminal Neuralgia ◽  
Nerve Block ◽  
Trigeminal Nerve ◽  
Viral Reactivation ◽  
Ocular Involvement ◽  
Eye Drops ◽  
Neurotrophic Keratitis ◽  
Trigeminal Block ◽  
Ophthalmic Branch

Herpes zoster ophthalmicus is commonly used to describe viral reactivation from the trigeminal ganglia with ocular involvement. The ophthalmic branch is the most commonly involved, whereas the maxillary and mandibular dermatomes are less commonly affected. Neurotrophic ulcer may occur secondary to intentional or inadvertent damage to the trigeminal nucleus, root, ganglion, or any segment of the ophthalmic branch of this cranial nerve. We report a case of reactivated maxillary herpes zoster combined with neurotrophic keratitis due to percutaneous 2nd and 3rd branch of trigeminal nerve block with alcohol to treat trigeminal neuralgia. A 57-year-old female came to the ophthalmology department complaining of decreased visual acuity and skin vesicle over the right lower lid and cheek. She had undergone right trigeminal nerve block for treatment of trigeminal neuralgia. Clinical examination revealed neurotrophic keratitis and maxillary herpes zoster. She was treated with oral and topical antivirals and vigorous lubrication with eye drops. Her neurotrophic keratitis showed a slow recovery. Although a few cases of herpes zoster following nerve block have been described, it would appear that a case of simultaneous maxillary herpes zoster and neurotrophic keratitis following trigeminal block has not yet been documented. It is possible that trigeminal nerve block may cause reactivation of latent virus and refractory neurotrophic keratitis.

scholarly journals Antiinflammatory therapy of neurotrophic corneal diseases

2019 ◽  
Vol 12 (4) ◽  
pp. 77-82
Author(s):  
E. V. Yani ◽  
E. N. Orlova ◽  
V. A. Golikova
Keyword(s):  
Combined Treatment ◽  
Eye Drops ◽  
Test Results ◽  
Antiinflammatory Therapy ◽  
Group Iii ◽  
Group I ◽  
New Directions ◽  
Neurotrophic Keratitis ◽  
Anti Inflammatory ◽  
Group Ii

Clinical data on new directions in combined treatment of neurotrophic keratitis, including anti-inflammatory therapy are presented.Purpose. To compare the effectiveness of bromfenac 0.09 %, nepafenac 0.1 % and indomethacin 0.1 % eye drops in the treatment of neurotrophic keratitis (NK).Materials and methods. 22 NK patients, aged 34 to 78, were divided into three groups. Group I received bromfenac 0.09 %, group II, nepafenac 0.1 %, and group III, indomethacin 0.1 %. Ophthalmic tests included visometry, biomicroscopy, corneal sensitivity determination, as well as diagnostic tests to determine indicators of tear production (Schirmer test, Norn test, LIPCOF test), and measuring lacrimal meniscus height.Results. Between visits V2 and V3, patients of group III showed an increase in conjunctival irritation to an average of 2.3 points, while groups I and II revealed the condition of the conjunctiva at 0.9 and 1.1 points, respectively. The lesion area was evaluated in points (max = 20) and averaged on V1 6.8 points in group I, 5.9 points in group II and 7.2 points in group III. Keratopathy in group I which was estimated at 3.8 points before V2, dropped to 1.4 points by V3. In group III it was 1.7 points by V3. In group II, keratopathy showed only 4.1 points by V3. The average Norn test on the day of treatment showed 2.7 seconds in group I, 2.5 seconds in group II, and 3.1 seconds in group III. No significant increase in Schirmer's test results in all groups was recorded.Conclusion. The use of non-steroidal anti-inflammatory eye drops of various groups — bromfenac 0.09%, nepafenac 0.1 % and indomethacin 0.1 % — gave a positive result in NK therapy. However, bromfenac 0.09% instillations administered once a day produce a higher anti-inflammatory effect then the same quantity of nepafenac 0.1% and indomethacin 0.1 % instillations.

scholarly journals Update On Cenegermin Eye Drops In The Treatment Of Neurotrophic Keratitis

2019 ◽  
Vol Volume 13 ◽  
pp. 1973-1980 ◽  
Author(s):  
Hosam Sheha ◽  
Sean Tighe ◽  
Omar Hashem ◽  
Yasutaka Hayashida
Keyword(s):  
Eye Drops ◽  
Neurotrophic Keratitis

Effects of Mydrin eye-drops on central corneal thickness values in adult patients with myopia

2016 ◽  
Vol 100 (2) ◽  
pp. 151-154 ◽  
Author(s):  
Yuan Zeng ◽  
Jian-Hua Gao
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Adult Patients ◽  
Eye Drops
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