scholarly journals Activation of MAPK and Cyclin D1/CDK4 in Malignant Transformation of Human Embryonic Lung Fibroblasts Induced by Silica and Benzopyrene

2020 ◽  
Vol 21 (2) ◽  
pp. 295-300
Author(s):  
Huan Wang ◽  
Shuyu Xiao ◽  
Yali Tang ◽  
Ke Han ◽  
Zheng Zhang ◽  
...  
Keyword(s):  
Cyclin D1 ◽  
Malignant Transformation ◽  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung

Genotoxic Effect of a New Water-Soluble Fullerene Derivative C70 and its Effect on the Transcriptional Activity of Genes that Regulate the Cell Cycle, DNA Repair and Apoptosis

2021 ◽  
Vol 1031 ◽  
pp. 222-227
Author(s):  
Ekaterina A. Savinova ◽  
Elizaveta S. Ershova ◽  
Olga A. Kraevaya ◽  
Pavel A. Troshin ◽  
S.V. Kostyuk
Keyword(s):  
Cell Cycle ◽  
Transcriptional Activity ◽  
Water Soluble ◽  
Lung Fibroblasts ◽  
Fullerene Derivative ◽  
Embryonic Lung ◽  
Dna Breaks ◽  
Human Embryonic Lung ◽  
Fullerene Derivatives ◽  
Cellular Dna

It is important to take into consideration the new fullerene derivatives genotoxicity. In the present is study, we analyzed the new water-soluble fullerene C70 (F350) effects on the human embryonic lung fibroblasts (HELF) oxidative damage and DNA breaks. We found that the studied compound causes cellular DNA damage and affects the transcriptional activity of cell cycle and cell apoptosis regulating genes.

Effects of MRI Contrast Agents on Human Embryonic Lung Fibroblasts

2010 ◽  
Vol 45 (9) ◽  
pp. 513-519 ◽  
Author(s):  
Benjamin Wiesinger ◽  
Rainer Kehlbach ◽  
Julie Bebin ◽  
Jennifer Hemsen ◽  
Rüdiger Bantleon ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung ◽  
Mri Contrast

scholarly journals Thalidomide inhibits the gene promoter of connective tissue growth factor in human embryonic lung fibroblasts

2020 ◽  
Vol 9 (5) ◽  
pp. 2516-2523
Author(s):  
Yonghui Wu ◽  
Libao Liu ◽  
Jian Zhang ◽  
Lei Huang ◽  
Shaohong Huang ◽  
...  
Keyword(s):  
Growth Factor ◽  
Connective Tissue ◽  
Connective Tissue Growth Factor ◽  
Gene Promoter ◽  
Tissue Growth ◽  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung

Toxic and DNA damaging effects of a functionalized fullerene in human embryonic lung fibroblasts

2016 ◽  
Vol 805 ◽  
pp. 46-57 ◽  
Author(s):  
E.S. Ershova ◽  
V.A. Sergeeva ◽  
A.I. Chausheva ◽  
D.G. Zheglo ◽  
V.A. Nikitina ◽  
...  
Keyword(s):  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung ◽  
Damaging Effects

Scatter factor from human embryonic lung fibroblasts is probably identical to hepatocyte growth factor

1991 ◽  
Vol 180 (2) ◽  
pp. 765-773 ◽  
Author(s):  
Tetsumi Konishi ◽  
Toyohiro Takehara ◽  
Takashi Tsuji ◽  
Keiichi Ohsato ◽  
Kunio Matsumoto ◽  
...  
Keyword(s):  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung ◽  
Scatter Factor ◽  
Hepatocyte Growth
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