Stereotactic Biopsy of Brainstem Lesion in Children: Techniques, Efficacy and Safety: Case Review of Single Institutional Experience

2021 ◽  
Vol 4 (2) ◽  
pp. 01-05
Author(s):  
Ugwuanyi U.C.

Introduction: Stereotactic biopsy of brain stem lesions in children evolved from a controversial background but the current trend seems towards a safe procedure that will yield diagnostic accuracy to guide targeted and individualized treatments. Aims and Objectives: To confirm safety, accuracy and usefulness of biopsy of brain stem lesions using our institutional experience on two index cases that underwent stereotactic procedures. Methodology: A review of two case reports were conducted to expose diagnostic success and procedure-related highpoints. Results: In both cases presented the procedure was uneventful, yielded the desired diagnostic tissue and there were no procedure related complications. Conclusion: Stereotactic biopsy of pediatric brain stem lesion is safe. Tissue sampling was accurate in both cases and served as a prerequisite more targeted oncology referral and potentially individualized treatment.

Neurosurgery ◽  
1989 ◽  
Vol 25 (6) ◽  
pp. 959-964 ◽  
Author(s):  
Corey Raffel ◽  
Gordon J. McComb ◽  
Sara Bodner ◽  
Floyd E. Gilles

Abstract The symptoms and clinical courses of 4 patients with neurofibromatosis and lesions of the brain stem identifiable on computed tomographic and/or magnetic resonance imaging scans are described. Two patients underwent biopsy and both had low-grade astrocytomas with no evidence of anaplasia. Both received radiation and chemotherapy. The other 2 patients have been monitored without biopsy or treatment. Three patients are alive and clinically stable, having been followed up for an average of 4 years; neuroimaging studies have shown no change in their tumors. The fourth patient died of a supratentorial primitive neuroectodermal tumor. Imaging studies had shown no change in his brain stem lesion, which at autopsy was found to be a focal collection of fibrillary astrocytes. These data suggest that some patients with brain stem lesions and neurofibromatosis may have a prognosis distinctly different from that of the typical patient with a brain stem glioma. We recommend caution against aggressive operative and adjuvant therapy for brain stem lesions in patients with neurofibromatosis, unless progression of the lesion is documented clinically and/or by imaging.


1988 ◽  
Vol 2 (2) ◽  
pp. 235-240 ◽  
Author(s):  
D. G. T. Thomas ◽  
R. Bradford ◽  
S. Gill ◽  
C. H. Davis

2004 ◽  
Vol 147 (1) ◽  
pp. 47-50 ◽  
Author(s):  
A. Shad ◽  
A. Green ◽  
S. Bojanic ◽  
T. Aziz

1985 ◽  
Vol 48 (1-6) ◽  
pp. 488-488 ◽  
Author(s):  
K.S. Sahni ◽  
N.R. Ghatak ◽  
Harold F. Young

2001 ◽  
Vol 44 (4) ◽  
pp. 226-229 ◽  
Author(s):  
E. J. Boviatsis ◽  
K. Voumvourakis ◽  
N. Goutas ◽  
K. Kazdaglis ◽  
C. Kittas ◽  
...  

1950 ◽  
Vol 2 (1-4) ◽  
pp. 483-498 ◽  
Author(s):  
D.B. Lindsley ◽  
L.H. Schreiner ◽  
W.B. Knowles ◽  
H.W. Magoun

Neurology ◽  
1976 ◽  
Vol 26 (8) ◽  
pp. 769-769 ◽  
Author(s):  
O. N. MARKAND ◽  
M. L. DYKEN

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