scholarly journals Effect of Pharmacy Counseling on Readmissions in Patients with Acute Exacerbations of COPD: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Narachai Prasungriyo ◽  
Nungruthai Sooksai
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Direct Costs ◽  
Disease Assessment ◽  
Chronic Obstructive ◽  
P Value ◽  
Intervention Period ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference ◽  
Acute Exacerbations

Objective: To investigate the effects of pharmacy counseling on clinical and economic outcomes in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) patients.Material and Methods: The outcomes consisted of 28-day hospital readmissions related to AECOPD, direct costs, medication adherence calculated by proportion of days covered (PDC), and health-related quality of life (HRQoL) measured by chronic obstructive pulmonary disease assessment test (CAT). The data derived from the intervention group, for which pharmacy counseling was provided, was compared with that obtained from the control group provided with usual pharmaceutical care. The study also drew comparisons between the PDC and CAT scores of pre- and postintervention periods.Results: Forty-four patients (23 intervention and 21 control) were included in the analysis. There were no significant differences in the readmission rate (13% vs 19%, p-value>0.050), nor the number of readmitted patients (3 vs 3, p-value >0.050). A decrease in direct costs did not reach statistical significance (p-value>0.050). In addition, no difference between the PDC scores was found (96.67 vs 100.00, p-value>0.050). Intervention patients obtained significantly lower CAT scores than the control patients did (9 vs 19, p-value<0.050). Compared with the pre-intervention period, PDC scores were identical; however, CAT scores measured during the post-intervention period were significantly different.Conclusion: Pharmacy counseling for AECOPD patients could enhance HRQoL. Drug therapy and pulmonary rehabilitation may cause such improvement. Further work, which has adequate participants, is required to detect a significant difference in readmissions between the two groups.

scholarly journals A randomized prospective study to compare the efficacy and safety of budesonide plus formoterol and tiotropium plus formoterol in patients having mild to moderate chronic obstructive pulmonary disease

2021 ◽  
Vol 10 (3) ◽  
pp. 245
Author(s):  
Chandra Veer Singh ◽  
Aditya Kumar Gautam ◽  
Alok Dixit ◽  
Amit Vikram Singh ◽  
Sandeep Kumar Singh
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
P Value ◽  
Efficacy And Safety ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference ◽  
Long Acting ◽  
Β2 Agonist

Background: Chronic obstructive pulmonary disease (COPD) is a leading respiratory illness affecting the quality of lives around the world. The present study aims to compare the efficacy and safety of combination of inhaled corticosteroid (ICS) and long acting β2 agonist (LABA) with long acting β2 agonist and long acting muscarinic antagonist (LAMA) in treatment of mild to moderate COPD in a tertiary care hospital.Methods: Total 132 patients with COPD were recruited on the basis of inclusion and exclusion criteria for 8 weeks study from outpatient clinic. A complete pulmonary examination including spirometry examination was done to rule out severe and very severe forms of COPD. Spirometry was performed at the time of recruitment for evaluation of forced expiratory volume in one second (FEV1) and measurement of SpO2 at the time of recruitment at 2 weeks and 8 weeks. Appropriate statistical methods were used to compare the qualitative and quantitative primary and secondary efficacy end points, p value <0.05 was considered significant.Results: On analysis, there was a significant difference (p<0.05) was observed in FEV1 and SpO2 from baseline in ICS plus LABA group (n=66). A similarly significant difference (p<0.05) was observed in LABA and LAMA group (n=66). On comparison between ICS plus LABA and LABA plus LAMA no significant difference in FEV1 and SpO2 was observed between the two groups.  More adverse drug reactions were observed in ICS plus LABA group than LAMA plus LABA group.Conclusions: Combination of ICS and LABA combination is as effective as combination of LABA and LAMA in patients having mild to moderate COPD. However, LABA and LAMA combination is preferable because it is associated with fewer side effects.

scholarly journals THE EFFECT OF PURSED LIPS BREATHING IN INCREASING OXYGEN SATURATION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN INTERNAL WARD 2 OF THE GENERAL HOSPITAL OF DR. R. SOEDARSONO PASURUAN

2017 ◽  
Vol 3 (3) ◽  
pp. 117-123
Author(s):  
Budiono Budiono ◽  
Mustayah Mustayah ◽  
Aindrianingsih Aindrianingsih
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oxygen Saturation ◽  
General Hospital ◽  
Pulmonary Disease ◽  
Sampling Technique ◽  
Nursing Intervention ◽  
Chronic Obstructive ◽  
P Value ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference

Background: Chronic obstructive pulmonary disease is a leading cause of death and disability. Thus, the effort to reduce the symptoms, such as dyspnea is necessity. Pursed lip breathing is assumed increasing oxygen saturation.Objective: This study aims to determine the effect of pursed lips breathing in increasing oxygen saturation in patients with COPD in internal ward 2 of the General Hospital of Dr. R. Soedarsono Pasuruan on May 16 - June 30, 2017.Methods: This was a pre-experimental design with pre-posttest design. There were 24 patients with COPD selected using simple random sampling technique. Pulse oximetry (oximeter pulse fingertip) was used to measure oxygen saturation. Data were analyzed using Wilcoxon Sign Rank Test.Results: Findings showed p-value 0.000 (0.05), which indicated that there was a statistically significant difference in oxygen saturation before and after pursed lips breathing.Conclusion: There was a significant effect of pursed lips breathing on oxygen saturation in patients with COPD in the internal ward 2 of the general hospital of Dr. R. Soedarsono Pasuruan. Thus, pursed lips breathing could be applied as a nursing intervention in patients with COPD.

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