scholarly journals Evaluation of Electron Specific Absorbed Fractions in Organs of Digimouse Voxel Phantom Using Monte Carlo Simulation Code FLUKA

2019 ◽  
Vol 9 (2Apr) ◽  
Author(s):  
A Sinha ◽  
N Singh ◽  
B M Dixit ◽  
N K Painuly ◽  
H K Patni ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Electron Energy ◽  
Absorbed Dose ◽  
Radiological Protection ◽  
Monte Carlo Code ◽  
Simulation Code ◽  
Human Organ ◽  
Voxel Phantom ◽  
Publication Number ◽  
Target Organs

Background: For preclinical evaluations of radiopharmaceuticals, most studies are carried out on mice. Values of electron specific absorbed fractions (SAF) have had vital role in the assessment of absorbed dose. In past studies, electron specific absorbed fractions were given for limited source target pairs using older reports of human organ compositions.Objective: Electron specific absorbed fraction values for monoenergetic electrons of energies 15, 50, 100, 500, 1000 and 4000 keV were evaluated for the Digimouse voxel phantom incorporated in Monte Carlo code FLUKA. The organ sources considered in this study were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal, eye and brain. The considered target organs were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal and brain. Eye and brain were considered as target organs only for eye and brain as source organs. From the latest report (International Commission on Radiological Protection ICRP) publication number 110, organ compositions and densities were adopted.Results: The electron specific absorbed fraction values for self-irradiation decreases with increasing electron energy. The electron specific absorbed fraction values for cross-irradiation are also found to be dependent on the electron energy and the geometries of source and target. Organ masses and electron specific absorbed fraction values are presented in tabular form. Conclusion: The results of this study will be useful in evaluating the absorbed dose to various organs of mice similar in size to the present study. 

Dose conversion coefficients for ICRP110 voxel phantom in the Geant4 Monte Carlo code

2014 ◽  
Vol 95 ◽  
pp. 309-312 ◽  
Author(s):  
M.C. Martins ◽  
T.P.V. Cordeiro ◽  
A.X. Silva ◽  
D. Souza-Santos ◽  
P.P. Queiroz-Filho ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Code ◽  
Voxel Phantom ◽  
Conversion Coefficients

37 Evaluation of the absorbed dose reporting mode of the AAA and AXB algorithms and the Monte-Carlo code GATE in high and low density media

2018 ◽  
Vol 56 ◽  
pp. 21-22
Author(s):  
T. Younes ◽  
A. Delbaere ◽  
M. Chauvin ◽  
L. Simon ◽  
G. Fares ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Absorbed Dose ◽  
Monte Carlo Code ◽  
Low Density

Cattle’s Thyroid Dose Estimation with Compartmental Model of Iodine Metabolism and Monte Carlo Transport Technique

2018 ◽  
pp. 48-54
Author(s):  
Ю. Кураченко ◽  
Yu. Kurachenko ◽  
Н. Санжарова ◽  
N. Sanzharova ◽  
Г. Козьмин ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Thyroid Gland ◽  
Compartmental Model ◽  
Radiation Transport ◽  
Absorbed Dose ◽  
Dose Calculation ◽  
Average Dose ◽  
Monte Carlo Code ◽  
Thyroid Dose ◽  
The Subject

Purpose: This work aims first to improve the reliability of absorbed dose calculation in critical organs of cattle during internal irradiation immediately after radiation accidents by a) improving the compartmental model of radionuclide metabolism in animal body; b) the use of precision computing technologies for modeling as the domain, and the actual radiation transport. In addition, the aim of the work is to determine the agreed values of the 131I critical dose in the cattle thyroid, leading to serious gland dysfunction and its follow-up destruction. Material and methods: To achieve aforecited goals, comprehensive studies were carried out to specify the parameters of the compartmental model, based on reliable experimental and theoretical data. Voxel technologies were applied for modeling the subject domain (thyroid gland and its environment). Finally, to solve the 131I radiation transport equation, the Monte Carlo code was applied, which takes into account the contribution of gamma and beta radiation source, and the contribution of the entire chain of secondary radiations in the dose calculation, up to the total energy dissipation. Results: As the main theoretical result, it is necessary to emphasize the conversion factor from the 131I activity, distributed uniformly in volume of the thyroid gland, to the average dose rate in the gland (Bq × Gy/s). This factor was calculated for both cows and calves in the selected domain configuration and thyroid morphology. The main practical result is a reliable estimation the lower bound of the absorbed dose in the thyroid, which in a short time leads to its destruction under internal 131I irradiation: ~300 Gy. Conclusion: Usage a compartmental model of the 131I metabolism with biokinetic parameters, received on the basis of reliable experimental data, and precise models of both the subject area and radiation transport for evaluation the dose in the cattle thyroid after the radiation accident allowed to obtain reliable values of the thyroid dose, adducting to its destruction at short notice.

scholarly journals Assessment of MCNPX Monte Carlo Code for Absorbed Dose Calculations in Mammogarphy Examination

2017 ◽  
Vol 17 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Huseyin Ozan Tekin ◽  
Asghar Mesbahi ◽  
Viswanath P. Singh ◽  
Umit Kara ◽  
Tugba Manici ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Absorbed Dose ◽  
Monte Carlo Code ◽  
Dose Calculations

Organ Dose Calculations Using ICRP Adult Voxel Phantoms and TRIPOLI-4 Monte Carlo Code

2020 ◽  
Vol 6 (4) ◽  
Author(s):  
Yi-Kang Lee
Keyword(s):  
Monte Carlo ◽  
Computational Models ◽  
Radiation Transport ◽  
Organ Dose ◽  
Radiation Shielding ◽  
Radiological Protection ◽  
Monte Carlo Code ◽  
Coupled Transport ◽  
Nuclear Data Library ◽  
Voxel Phantoms

Abstract The ICRP 110 adult male and female voxel phantoms are the official computational models representing the ICRP (International Commission on Radiological Protection) Reference Male and Reference Female. In 2018, the Working Group 6 (WG6) of European Radiation Dosimetry Group (EURADOS) organized a study on the usage of the ICRP voxel reference phantoms. Organ dose calculation tasks with radiation transport codes were proposed in occupational, environmental, and medical dosimetry. The TRIPOLI-4 Monte Carlo radiation transport code has been widely used in radiation shielding, criticality safety, and reactor physics fields for supporting French nuclear energy research and industrial applications. To enhance the application fields of TRIPOLI-4, the 2018 EURADOS-WG6 tasks are being taken into account by using different features of the TRIPOLI-4 code. In this work, the ICRP reference voxel phantoms were first adapted into TRIPOLI-4. More than 14 × 106 voxels were represented in a mixed lattice geometry including 140 organs-tissues and 52 tissue media. Diverse exposure scenarios were then investigated by using 60Co and 241Am gamma-ray sources, 16N beta source, and 10 keV neutron source. The TRIPOLI-4 standard nuclear data library was utilized on these neutron, photon, electron, and positron-coupled transport calculations. Energy deposition estimators for electron, positron, neutron, and photon coupled with mesh tally options were used to calculate the organ absorbed dose DT and the effective dose E. TRIPOLI-4 calculation methods and primary results for the EURADOS-WG6 voxel phantom exercise on organ dose study tasks are reported here.

GATE MODELING OF LATERAL SCATTERING OF PROTON PENCIL BEAMS

2020 ◽  
Vol 189 (1) ◽  
pp. 76-88
Author(s):  
Shiva Zarifi ◽  
Hadi Taleshi Ahangari ◽  
Sayyed Bijan Jia ◽  
Mohammad Ali Tajik-Mansoury ◽  
Milad Najafzadeh
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Energy Range ◽  
Ionization Potential ◽  
Gaussian Function ◽  
Gaussian Model ◽  
Absorbed Dose ◽  
Body Tissue ◽  
Simulation Code ◽  
Optimal Value

Abstract To validate the GATE Monte Carlo simulation code and to investigate the lateral scattering of proton pencil beams in the major body tissue elements in the therapeutic energy range. In this study, GATE Monte Carlo simulation code was used to compute absorbed dose and fluence of protons in a water cubic phantom for the clinical energy range. To apply the suitable physics model for simulation, different physics lists were investigated. The present research also investigated the optimal value of the water ionization potential as a simulation parameter. Thereafter, the lateral beam profile of proton pencil beams were simulated at different energies and depths in body tissue elements. The range results obtained using the QGSP_BIC_EMY physics showed the best compatibility with the NIST database data. Moreover, it was found that the 76 eV is the optimal value for the water ionization potential. In the next step, it was shown that the beam halo can be described by adding a supplementary Gaussian function to the standard single-Gaussian model, which currently is used by treatment planning systems (TPS).

scholarly journals Towards muon-electron scattering at NNLO

2020 ◽  
Vol 2020 (11) ◽  
Author(s):  
Carlo M. Carloni Calame ◽  
Mauro Chiesa ◽  
Syed Mehedi Hasan ◽  
Guido Montagna ◽  
Oreste Nicrosini ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Electron Scattering ◽  
Photon Radiation ◽  
Monte Carlo Code ◽  
Radiative Corrections ◽  
Small Momentum Transfer ◽  
Simulation Code ◽  
Theoretical Formulation ◽  
Loop Contribution ◽  
The Impact

Abstract The recently proposed MUonE experiment at CERN aims at providing a novel determination of the leading order hadronic contribution to the muon anomalous magnetic moment through the study of elastic muon-electron scattering at relatively small momentum transfer. The anticipated accuracy of the order of 10ppm demands for high-precision predictions, including all the relevant radiative corrections. The theoretical formulation for the fixed-order NNLO photonic radiative corrections is described and the impact of the numerical results obtained with the corresponding Monte Carlo code is discussed for typical event selections of the MUonE experiment. In particular, the gauge-invariant subsets of corrections due to electron radiation as well as to muon radiation are treated exactly. The two-loop contribution due to diagrams where at least two virtual photons connect the electron and muon lines is approximated taking inspiration from the classical Yennie-Frautschi-Suura approach. The calculation and its Monte Carlo implementation pave the way towards the realization of a simulation code incorporating the full set of NNLO corrections matched to multiple photon radiation, that will be ultimately needed for data analysis.

Dual-energy contrast-enhanced digital mammography: Glandular dose estimation using a Monte Carlo code and voxel phantom

2015 ◽  
Vol 31 (7) ◽  
pp. 785-791 ◽  
Author(s):  
E. Tzamicha ◽  
E. Yakoumakis ◽  
I.A. Tsalafoutas ◽  
A. Dimitriadis ◽  
E. Georgiou ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Digital Mammography ◽  
Dual Energy ◽  
Monte Carlo Code ◽  
Dose Estimation ◽  
Voxel Phantom ◽  
Contrast Enhanced
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