Ependymal cyst producing alpha-fetoprotein

2000 ◽  
Vol 93 (4) ◽  
pp. 682-685 ◽  
Author(s):  
Ryuzaburo Kanazawa ◽  
Kazunari Kogure ◽  
Shushi Kominami ◽  
Shiro Kobayashi ◽  
Akira Teramoto ◽  
...  
Keyword(s):  
Third Ventricle ◽  
Single Layer ◽  
Cystic Mass ◽  
Pineal Region ◽  
Alpha Fetoprotein ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Content Type ◽  
Serum Alpha Fetoprotein ◽  
Resected Tissue

✓ This 17-year-old man was admitted to the hospital due to progressive headache and diplopia. Neuroradiological studies revealed a cystic mass in the pineal region without a parenchymal lesion. In addition, serum alpha-fetoprotein (AFP) levels were elevated. A cyst-to-third-ventricle and cistern fenestration was performed, but the cyst enlarged 3 months after the first operation. In the second operation, subtotal resection of the cyst was performed. The AFP level in the cyst fluid was very high preoperatively but was decreased postoperatively. The patient was discharged with no neurological deficit. Pathological examination of resected tissue showed a single layer of cuboidal cells that resembled an ependymal structure. The cells were immunoreactive for AFP immunostain, which indicated AFP production from these cells.

Third ventricular choroid plexus papilloma with psychosis

1997 ◽  
Vol 87 (1) ◽  
pp. 103-105 ◽  
Author(s):  
Benjamin S. Carson ◽  
Jon D. Weingart ◽  
Michael Guarnieri ◽  
Paul G. Fisher
Keyword(s):  
Choroid Plexus ◽  
Behavioral Problems ◽  
Third Ventricle ◽  
Choroid Plexus Papilloma ◽  
Pathological Examination ◽  
Psychiatric Evaluation ◽  
Content Type ◽  
Resected Tumor ◽  
History Of ◽  
Plexus Papilloma

✓ This 9-year-old boy with a history of behavioral problems and worsening psychosis responded initially to treatment with haloperidol. However, a magnetic resonance image obtained as part of his psychiatric evaluation revealed an anterior third ventricle tumor and mild-to-moderate hydrocephalus. The resected tumor was found on pathological examination to be a choroid plexus papilloma. The patient had an uneventful postoperative course and remained free of psychosis or mood disorder at 1-year follow-up examination.

Choroid plexus carcinoma presenting as an intraparenchymal mass

2001 ◽  
Vol 95 (6) ◽  
pp. 1040-1044 ◽  
Author(s):  
Alexis Byrne Carter ◽  
Donald L. Price ◽  
Keith A. Tucci ◽  
Gregory K. Lewis ◽  
Jeffrey Mewborne ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Skull Fracture ◽  
Ct Scanning ◽  
Cystic Mass ◽  
Choroid Plexus Carcinoma ◽  
Left Frontal Lobe ◽  
Content Type ◽  
Resected Tissue ◽  
History Of ◽  
The Brain

✓ A 6-year-old girl with a history of a nondisplaced skull fracture diagnosed with computerized tomography (CT) scanning 3 years previously presented with a 6-week history of headaches and decreased use of her right side. On admission CT scans, a large cystic mass was identified in the left frontal lobe region of the brain. A connection between the mass and the ventricular system was not seen on radiological examination or during surgery. Gross-total resection of the mass was achieved. The histological and immunohistochemical findings in the resected tissue confirmed a diagnosis of choroid plexus carcinoma (ChPC). This is the first reported case of a ChPC arising in an extraventricular location not associated with the choroid plexus.

Suprasellar germinoma

1978 ◽  
Vol 49 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Juji Takeuchi ◽  
Hajime Handa ◽  
Izumi Nagata
Keyword(s):  
Third Ventricle ◽  
Plasma Concentrations ◽  
Pineal Region ◽  
Content Type ◽  
Intracranial Germinoma ◽  
Suprasellar Germinoma ◽  
Neuroradiological Examination ◽  
Tomography Scanning ◽  
Visual Disturbances

✓ The clinical features of 18 cases of suprasellar germinoma were reviewed, and the following points stressed: 1) The incidence of intracranial germinoma and teratoma seems to be much higher in Japan than elsewhere. 2) Germinomas in the pineal region, the third ventricle, and the lateral ventricle were observed to be predominant in males. In suprasellar germinoma, however, males were not affected predominantly and the male:female ratio was 1:1. 3) Suprasellar germinomas caused three symptoms: diabetes insipidus, visual disturbances, and pituitary dysfunctions. 4) Pituitary functions were disturbed to various degrees. Some cases showed hypopituitarism but some showed an elevation of plasma concentrations of cortisol or luteinizing hormone and follicle stimulating hormone. 5) Some abnormalities showing a suprasellar mass were usually found on neuroradiological examination. 6) Suprasellar germinomas were very sensitive to radiotherapy and some of them rapidly disappeared on follow-up computerized tomography scanning after irradiation with as little as 1200 rads.

Histiocytic lesion mimicking intrinsic brainstem neoplasm

1999 ◽  
Vol 91 (6) ◽  
pp. 1037-1040 ◽  
Author(s):  
Kyle D. Weaver ◽  
Diane Armao ◽  
Joseph M. Wiley ◽  
Matthew G. Ewend
Keyword(s):  
Differential Diagnosis ◽  
Fourth Ventricle ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Imaging Studies ◽  
Content Type ◽  
Brainstem Lesions ◽  
History Of ◽  
Initial Imaging ◽  
Fine Print

✓ This 10-year-old girl presented with a 1-month history of progressive bulbar palsy and a solitary enhancing mass originating within the floor of the fourth ventricle. Results of initial imaging studies and presentation were suggestive of neoplasia. Subtotal resection was performed and pathological examination revealed the mass to be a histiocytic lesion, with no evidence of a glioma. The patient had no other stigmata of histiocytosis and was treated with steroid medications, resulting in prolonged resolution of the lesion. This case demonstrates that for discrete brainstem lesions the differential diagnosis includes entities other than glioma for which treatment is available. Biopsy sampling should be considered when technically feasible.

scholarly journals Reinvestigation of the origins of pineal meningiomas based on its related veins and arachnoid membranes

2019 ◽  
Author(s):  
Lei Yu ◽  
Berdimyrat Orazmyradov ◽  
Songtao Qi ◽  
Ye Song ◽  
Luxiong Fang
Keyword(s):  
Posterior Part ◽  
Vertical Motion ◽  
Pineal Region ◽  
Video Data ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Cerebral Vein ◽  
Straight Sinus ◽  
Velum Interpositum ◽  
Medical University

Abstract Background: A series of patients harboring pineal region meningiomas were respectively analyzed to explore the origin of these tumors and the true meaning of the term "velum interpositum (VI) meningiomas".Methods: 21 patients with pineal meningiomas underwent operation in Nanfang Hospital of Southern Medical University from January 2005 to December 2016 were retrospectively included to analyze the clinical features, imaging findings and surgical video data of these patients. According to the method of literature, the data of this group were also divided into falcotentorial (FT) meningiomas and VI meningiomas, and the differences between the two types of tumors were compared.Results: Among the 21 cases of tumor, there were 12 cases of FT meningiomas, including 4 cases originating from cerebral falx, 4 cases from tentorium of cerebellum and 4 cases from straight sinus; there were 9 cases of VI meningiomas, 7 of which originated from the arachnoid sleeve of the Galen vein, 1 from the posterior part of the internal cerebral vein and 1 from the posterior surface of the pineal gland. Postoperative pathological examination showed meningiomas in all the 21 patients, including 16 cases of total resection and 5 cases of subtotal resection. Postoperatively limitation of binocular vertical motion was found in 3 cases, homotropic hemianopia in 7 cases, hemiplegia in 1 case and death in 1 case.Conclusions: This study suggests that pineal meningiomas are more suitable to be described by FT meningioma and primary pineal meningiomas by analyzing the origin of tumors. The term "VI meningiomas" can not accurately reflect the origin of pineal meningiomas. Before the removal of pineal meningiomas, more attention should be paid to the effects of the two types of tumors on the Galen vein and the straight sinus, and the establishment of venous collateral circulation.

Tuberculoma mimicking a pinealoma

1983 ◽  
Vol 59 (5) ◽  
pp. 875-878 ◽  
Author(s):  
Ian R. Whittle ◽  
John L. Allsop ◽  
Michael Besser
Keyword(s):  
Obstructive Hydrocephalus ◽  
Pineal Region ◽  
Subtotal Resection ◽  
Third Ventriculostomy ◽  
Antituberculous Therapy ◽  
Content Type ◽  
Pineal Region Tumors ◽  
Serial Ct ◽  
Cerebral Tuberculoma ◽  
Fine Print

✓ Computerized tomography (CT) revealed obstructive hydrocephalus and a pineal mass in a 14-year-old girl who presented with headaches and a Parinaud's syndrome. Although there was no major evidence of extracranial tuberculosis, and cerebrospinal fluid obtained during third ventriculostomy contained no leukocytes, suboccipital transtentorial biopsy of the lesion revealed it to be a tuberculoma. Serial CT scans showed resolution of the lesion following subtotal resection and antituberculous therapy. The implications of this case with regard to difficulties in the diagnosis of cerebral tuberculoma and the management of pineal region tumors are discussed.

scholarly journals Reinvestigation of the origins of pineal meningiomas based on its related veins and arachnoid membranes

2020 ◽  
Author(s):  
Lei Yu ◽  
Berdimyrat Orazmyradov ◽  
Songtao Qi ◽  
Ye Song ◽  
Luxiong Fang
Keyword(s):  
Posterior Part ◽  
Vertical Motion ◽  
Pineal Region ◽  
Video Data ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Cerebral Vein ◽  
Straight Sinus ◽  
Velum Interpositum ◽  
Medical University

Abstract Background : A series of patients harboring pineal region meningiomas were respectively analyzed to explore the origin of these tumors and the true meaning of the term "velum interpositum (VI) meningiomas". Methods: 21 patients with pineal meningiomas underwent operation in Nanfang Hospital of Southern Medical University from January 2005 to December 2016 were retrospectively included to analyze the clinical features, imaging findings and surgical video data of these patients. According to the method of literature, the data of this group were also divided into falcotentorial (FT) meningiomas and VI meningiomas, and the differences between the two types of tumors were compared. Results: Among the 21 cases of tumor, there were 12 cases of FT meningiomas, including 4 cases originating from cerebral falx, 4 cases from tentorium of cerebellum and 4 cases from straight sinus; there were 9 cases of VI meningiomas, 7 of which originated from the arachnoid sleeve of the Galen vein, 1 from the posterior part of the internal cerebral vein and 1 from the posterior surface of the pineal gland. Postoperative pathological examination showed meningiomas in all the 21 patients, including 16 cases of total resection and 5 cases of subtotal resection. Postoperatively limitation of binocular vertical motion was found in 3 cases, homotropic hemianopia in 7 cases, hemiplegia in 1 case and death in 1 case. Conclusions : This study suggests that pineal meningiomas are more suitable to be described by FT meningioma and meningiomas of the arachnoid of the pineal region by analyzing the origin of tumors. The term "VI meningiomas" can only reflect a part of meningiomas of the arachnoid of the pineal region. Before the removal of pineal meningiomas, more attention should be paid to the effects of the two types of tumors on the Galen vein and the straight sinus, and the establishment of venous collateral circulation.

Malignant pineal region tumors

1979 ◽  
Vol 51 (5) ◽  
pp. 597-607 ◽  
Author(s):  
Edward A. Neuwelt ◽  
Mark Glasberg ◽  
Eugene Frenkel ◽  
W. Kemp Clark
Keyword(s):  
Metastatic Tumor ◽  
Tumor Burden ◽  
Pineal Region ◽  
Subtotal Resection ◽  
Pineal Tumor ◽  
Pineal Tumors ◽  
Content Type ◽  
Pineal Region Tumors ◽  
Tissue Diagnosis ◽  
Craniospinal Radiation

✓ Eight patients with primary malignant pineal tumors have been seen at this institution over the past 6 years; six of them underwent definitive surgical exploration. Complete gross microsurgical excision of well encapsulated tumors was possible in four of these patients. In two cases of pineal germinomas, a biopsy and a subtotal resection were carried out because of the known radiosensitivity of this tumor. These six surgical patients all received postoperative craniospinal radiation and continue to do well up to 6 years postoperatively. Two nonoperative patients were initially treated at other institutions by ventriculoperitoneal shunt and radiation and were the only ones to develop metastatic disease. One patient had metastasis of her pineoblastoma to her unirradiated spinal canal and the other patient had metastasis of his germinoma to the peritoneum. The former patient was quadriplegic on admission, although her pineal tumor was no longer visible on computerized tomography (CT), and she died of pneumonia. The latter patient's tumor secreted the beta chain of human chorionic gonadotropin (HCG). This patient's massive metastatic tumor burden completely regressed as determined by body CT scan and HCG levels after four courses of chemotherapy with bleomycin, vinblastine, and cis-platinum. In 20 patients with lesions of the pineal region, craniotomy was associated with only one death (a patient with metastatic adenocarcinoma). Thus, microsurgery for pineal tumors provides either a reasonably safe potential for complete tumor extirpation and possible cure, or a tissue diagnosis which is necessary for appropriate therapeutic planning for radiotherapy and/or chemotherapy. The traditional therapeutic approach of empiric radiotherapy without a tissue diagnosis for pineal lesions may no longer be warranted.

Mixed germ-cell tumor of the pineal region

1987 ◽  
Vol 66 (2) ◽  
pp. 300-304 ◽  
Author(s):  
Stephen L. Graziano ◽  
Frank P. Paolozzi ◽  
Alfred R. Rudolph ◽  
William A. Stewart ◽  
Ahmad Elbadawi ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Serum Levels ◽  
Pineal Region ◽  
Cell Tumor ◽  
Subtotal Resection ◽  
Content Type ◽  
Mixed Germ Cell Tumor ◽  
Nongerminomatous Germ Cell Tumor ◽  
Modality Approach

✓ The case is presented of a 15-year-old boy with a mixed nongerminomatous germ-cell tumor of the pineal region associated with elevated cerebrospinal fluid and serum levels of the beta subunit of human chorionic gonadotropin. Treatment consisted of initial subtotal resection followed by radiotherapy and systemic chemotherapy with cisplatin, vinblastine, and bleomycin. The patient is alive without evidence of tumor 37 months after his initial diagnosis. A literature review of intracranial embryonal carcinoma and choriocarcinoma provided the rationale for a combined-modality approach to this otherwise lethal neoplasm.

scholarly journals Reinvestigation of the origins of pineal meningiomas based on its related veins and arachnoid membranes

2020 ◽  
Author(s):  
Lei Yu ◽  
Berdimyrat Orazmyradov ◽  
Songtao Qi ◽  
Ye Song ◽  
Luxiong Fang
Keyword(s):  
Posterior Part ◽  
Vertical Motion ◽  
Pineal Region ◽  
Video Data ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Cerebral Vein ◽  
Straight Sinus ◽  
Velum Interpositum ◽  
Medical University

Abstract Background: A series of patients harboring pineal region meningiomas were respectively analyzed to explore the origin of these tumors and the true meaning of the term "velum interpositum (VI) meningiomas".Methods: 21 patients with pineal meningiomas underwent operation in Nanfang Hospital of Southern Medical University from January 2005 to December 2016 were retrospectively included to analyze the clinical features, imaging findings and surgical video data of these patients. According to the method of literature, the data of this group were also divided into falcotentorial (FT) meningiomas and VI meningiomas, and the differences between the two types of tumors were compared.Results: Among the 21 cases of tumor, there were 12 cases of FT meningiomas, including 4 cases originating from cerebral falx, 4 cases from tentorium of cerebellum and 4 cases from straight sinus; there were 9 cases of VI meningiomas, 7 of which originated from the arachnoid sleeve of the Galen vein, 1 from the posterior part of the internal cerebral vein and 1 from the posterior surface of the pineal gland. Postoperative pathological examination showed meningiomas in all the 21 patients, including 16 cases of total resection and 5 cases of subtotal resection. Postoperatively limitation of binocular vertical motion was found in 3 cases, homotropic hemianopia in 7 cases, hemiplegia in 1 case and death in 1 case.Conclusions: This study suggests that pineal meningiomas are more suitable to be described by FT meningioma and meningiomas of the arachnoid of the pineal region by analyzing the origin of tumors. The term "VI meningiomas" can only reflect a part of meningiomas of the arachnoid of the pineal region. Before the removal of pineal meningiomas, more attention should be paid to the effects of the two types of tumors on the Galen vein and the straight sinus, and the establishment of venous collateral circulation.

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