Multicentric intracranial smooth-muscle tumor in a woman with human immunodeficiency virus

2000 ◽  
Vol 93 (4) ◽  
pp. 701-703 ◽  
Author(s):  
Jonathan S. Citow ◽  
Leonard Kranzler

✓ A 31-year-old woman with acquired immunodeficiency syndrome (AIDS) was found to harbor both a pulmonary smooth-muscle tumor and an intracranial extraaxial smooth-muscle tumor of the parasellar region. The frequency of smooth-muscle tumors (leiomyoma and leiomyosarcoma) has increased with AIDS, but much more so in children than in adults. Only nine cases of human immunodeficiency virus—related smooth-muscle tumors have been previously reported in adults, and only one of these was located intracranially.

2004 ◽  
Vol 7 (2) ◽  
pp. 198-203 ◽  
Author(s):  
Shimareet Kumar ◽  
Mariarita Santi ◽  
Gilbert Vezina ◽  
Tena Rosser ◽  
Roma S. Chandra ◽  
...  

We describe the clinicopathologic features of an Epstein-Barr virus (EBV)-associated smooth muscle tumor arising in the basal ganglia of a 10-year-old human immunodeficiency virus (HIV)-positive child. Only a few cases of intracranial smooth muscle tumors are reported in the literature and virtually all of these have been extra-axial, involving the dura or sinuses in HIV+ adults. Our case underscores the need to include an EBV-associated smooth muscle tumor in the differential diagnosis when evaluating intracranial mass lesions in immunodeficient children.


2000 ◽  
Vol 92 (1) ◽  
pp. 161-164 ◽  
Author(s):  
Prasad S. S. V. Vannemreddy ◽  
Marjorie Fowler ◽  
Richard S. Polin ◽  
John R. Todd ◽  
Anil Nanda

✓ Malignant glioma is the most common primary brain neoplasm, but generally it is not included in the differential diagnosis of enhancing lesions of the central nervous system (CNS) in patients suffering from acquired immunodeficiency syndrome. We report a case of glioblastoma multiforme (GBM) in a 29-year-old man with human immunodeficiency virus (HIV). Primary CNS lymphoma was suspected, making a definitive histological diagnosis crucial. An initial stereotactic biopsy sample was insufficient to establish a diagnosis and a second biopsy of the lesion was obtained. The histopathological investigation confirmed GBM and adjuvant external radiation treatment was given to the patient, who survived for 4 months after the initial biopsy. A decline in the rate of Toxoplasma infection and the changing diseases observed in HIV infection indicate the importance of obtaining a biopsy in cases of CNS mass lesions.


PEDIATRICS ◽  
1992 ◽  
Vol 90 (3) ◽  
pp. 460-463
Author(s):  
BRIGITTA U. MUELLER ◽  
KARINA M. BUTLER ◽  
M. COLLEEN HIGHAM ◽  
ROBERT N. HUSSON ◽  
KAREN A. MONTRELLA ◽  
...  

Neoplastic disease is an increasing problem in adults with the acquired immunodeficiency syndrome (AIDS). Kaposi's sarcoma is the indicator disease in 9% and lymphoma in 3% of adult AIDS cases.1 Indeed, the estimated incidence rate of non-Hodgkin's lymphomas (NHLs) reaches almost 50% in adult patients who have survived for up to 3 years while receiving antiretroviral therapy and who have a CD4 count below 50 cells/mm3.2 Children with human immunodeficiency virus (HIV) infection have also been treated and followed up for an extended period of time, but a similar increase in the incidence of malignancies has not yet been described. Through December 1990, only 17 children with NHL and 1 child with Kaposi's sarcoma as AIDS-indicator disease have been reported to the Centers of Disease Control.1


2007 ◽  
Vol 17 (6) ◽  
pp. 1333-1337 ◽  
Author(s):  
S. Khunamornpong ◽  
K. Sukpan ◽  
P. Suprasert ◽  
S. Shuangshoti ◽  
J. Pintong ◽  
...  

Smooth muscle tumors in immunocompromised patients have a strong association with Epstein-Barr virus (EBV) infection. EBV-associated smooth muscle tumors (EBV-SMT) are considered as a distinct group of smooth muscle tumors with different clinicopathologic features from conventional smooth muscle tumors. A 31-year-old female patient presented with a 2-cm mass at the left labium majus, the clinical diagnosis of which was a Bartholin lesion. She had acquired immunodeficiency syndrome diagnosed 29 months before. Excisional biopsy revealed a cellular tumor composed of round- to spindle-shaped cells with mild to moderate nuclear atypia. The tumor cells were immunoreactive for smooth muscle actin and muscle actin (HHF-35). Evidence of EBV infection was confirmed by in situ hybridization for EBV-encoded small RNA-1. To our knowledge, this is the first case of EBV-SMT presenting as a vulvar mass. EBV-SMT should be included in the differential diagnoses of mesenchymal tumor in patients with immunosuppression and in the differential diagnoses of smooth muscle tumor in uncommon sites, including the vulva.


2017 ◽  
Vol 5 (2) ◽  
pp. 1-12
Author(s):  
Nur Syamsi NL

AIDS (Acquired Immunodeficiency Syndrome) adalah syndrom yang timbul akibat adanya virus HIV (Human Immunodeficiency Virus) yang menyerang sistem kekebalan tubuh manusia. HIV/AIDS dapat menular melalui darah, sperma, cairan vagina, dan ASI (Air Susu Ibu). Penelitian ini dilakukan di Akademi Kebidanan Sandi Karsa Makassar yang terletak di jalan Bung lorong 2, Kelurahan Tamalanrea, Kecamatan Tamalanrea Jaya, Makassar. Jenis penelitian yang digunakan dalam penelitian ini bersifat deskriptif. Besarnya sampel yang digunakan adalah 30 responden dari 600 populasi yang dipilih secara Total Sampling. Di mana dalam pengambilan data digunakan instrumen berupa kuesioner yang dibagikan kepada responden. Dari keseluruhan responden didapatkan tingkat pengetahuan mahasiswa Akademi Kebidanan Sandi Karsa Makassar yang diteliti didapat 15 mahasiswa (50%) yang tingkat pengetahuan baik tentang HIV/AIDS dan terdapat 14 mahasiswa (46,7%) yang tingkat pengetahuan cukup tentang HIV/AID dan terdapat 1 mahasiswa (3,3%) yang tingkat pengetahuan kurang tentang HIV/AIDS


2021 ◽  
Vol 9 ◽  
pp. 232470962110146
Author(s):  
Roopam Jariwal ◽  
Nadia Raza ◽  
Janpreet Bhandohal ◽  
Everardo Cobos

Plasmablastic lymphoma (PBL) is a subtype of non-Hodgkin’s lymphoma that manifests in patients with the diagnosis of human immunodeficiency virus (HIV), more prominently in the head, neck, and oral mucosal region. The diagnosis of this rare lymphoma serves as a concomitant diagnosis of acquired immunodeficiency syndrome. The case is of a 33-year-old previously healthy male, with an unknown diagnosis of HIV with a painful right mandibular mass. He was subsequently diagnosed with PBL and HIV. This case of PBL illustrates the importance of linking a rare and potentially life-threatening diagnosis as a possible first manifestation of HIV.


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