METHYL METHACRYLATE AS FUNCTIONAL MONOMER FOR ETHYLMORPHINE-IMPRINTED POLYMERS IN BUTANOL USING BULK AND PRECIPITATION POLYMERIZATION

2021 ◽  
Vol 14 (01) ◽  
pp. 424-432
Author(s):  
S.A. Ramadhan ◽  
D. Fauzi ◽  
B.Z. Witka ◽  
D. Rahayu ◽  
A. N. Hasanah
Keyword(s):  
Methyl Methacrylate ◽  
Precipitation Polymerization ◽  
Functional Monomer ◽  
Imprinted Polymers

scholarly journals Synthesis of Atenolol-Imprinted Polymers with Methyl Methacrylate as Functional Monomer in Propanol Using Bulk and Precipitation Polymerization Method

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Aliya Nur Hasanah ◽  
Traju Ningtias Dwi Utari ◽  
Rimadani Pratiwi
Keyword(s):  
Methyl Methacrylate ◽  
Solid Phase ◽  
Bulk Polymerization ◽  
Drug Analysis ◽  
Precipitation Polymerization ◽  
Functional Monomer ◽  
Serum Samples ◽  
Imprinted Polymers ◽  
Polymerization Method ◽  
Spiked Serum

Atenolol is one of the beta-1 blocker drugs that is misused by athletes to increase their performance during competition. Therefore, it is important to analyze atenolol levels in blood selectively. The preparation method that can be used in separating atenolol in sample is molecular imprinting solid-phase extraction (MI-SPE) because it has good selectivity and sensitivity. This study aims to examine the characteristics and analytical performance of imprinted polymers synthesized from functional monomer methyl methacrylate. The stages of this study include the determination of association constants, synthesis of sorbent MI-SPE atenolol using the bulk polymerization method, and precipitation with atenolol as the template, methyl methacrylate as the functional monomer, and propanol as the porogen. The template was extracted from a polymer, and then, the adsorption ability, capacity, and selectivity of MI-SPE and finally the application of the best MI-SPE to spiked serum samples were determined. MI-SPE was also characterized by using Fourier-transform instrument infrared (FTIR) and scanning electron microscope (SEM). The result of characterization with FTIR and SEM showed that MIP made by the precipitation polymerization method was completely polymerized, more porous, and produced smaller particle size with an average value of 0.274 μm. It had better analytic performances than MIP made by bulk polymerization, with affinity value 0.3607 mg/g and homogeneity value 1.3246, and good selectivity toward atenolol with imprinting factor value 22.519. Application of MI-SPE to spiked serum samples has an excellent recovery percentage of 95.46% over 0% for the nonimprinting one. Based on the result of study, MIP made by precipitation polymerization could be used to extract atenolol on serum samples toward drug analysis.

scholarly journals Pyrogallol-imprinted polymers with methyl methacrylate via precipitation polymerization

2018 ◽  
Author(s):  
Faizatul Shimal Mehamod ◽  
Nor Amira Othman ◽  
Ku Halim Ku Bulat ◽  
Faiz Bukhari Mohd Suah
Keyword(s):  
Methyl Methacrylate ◽  
Precipitation Polymerization ◽  
Imprinted Polymers

Uiformly-Sized, Molecularly Imprinted Polymers for Naproxen by Precipitation Polymerization

2011 ◽  
Vol 399-401 ◽  
pp. 713-717 ◽  
Author(s):  
Xu Hong Jiang ◽  
Zhan Mei Liu
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Precipitation Polymerization ◽  
Polymer Microspheres ◽  
Functional Monomer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Recognition Ability ◽  
Cross Linker ◽  
Average Size ◽  
Polymerization Method

Uniformly-sized, molecularly imprinted polymers (MIPs) for (D)-naproxen have been prepared by a precipitation polymerization method using methacrylic acid (MAA) as a functional monomer and divinylbenzene (DVB) as a cross-linker in acetonitrile or a mixture of toluene and acetonitrile(1:3). The (D)-naproxen-imprinted MAA-co-DVB polymers were monodispersed microspheres with size in the range of 1.5 to 3.6µm. Enantioseparation of naproxen was attained using the (D)-naproxen-imprinted MAA-co-DVB polymer microspheres. When Ethylene glycol dimethacrylate(EGDMA) was used as a cross-linker, the MAA-co -EGDMA polymers were sub-microspheres with the average size of 350nm and showed very low affinity for the template (D)-naproxen . The (D)-naproxen-imprinted MAA-co-DVB polymer microspheres prepared in the mixture of toluene showed the highest molecular recognition ability and with the biggest size of 3.6µm.

scholarly journals A Novel Molecular Imprint Polymer Synthesis for Solid Phase Extraction of Andrographolide

2019 ◽  
Vol 19 (1) ◽  
pp. 219
Author(s):  
Hemavathi Krishnan ◽  
A.K.M. Shafiqul Islam ◽  
Zainab Hamzah ◽  
Pubalan Nadaraja ◽  
Mohd Noor Ahmad
Keyword(s):  
Solid Phase Extraction ◽  
Solid Phase ◽  
Computational Study ◽  
Bioactive Compound ◽  
Precipitation Polymerization ◽  
Isotherm Models ◽  
Phase Extraction ◽  
Functional Monomer ◽  
Imprinted Polymers ◽  
Molecular Imprint

The use of molecularly imprinted polymers for Solid phase micro-extraction (SPME) of bioactive compounds are getting popularity. The interest on efficient extraction process of andrographolide from the plant is increasing due to their vast therapeutic applications. In this study, andrographolide imprinted MIP was prepared by precipitation polymerization method using the non-covalent technique to use as sorbent materials for solid phase extraction of the bioactive compound. HyperChem 8.0.10 software was used to investigate and optimize the template and functional monomer ratio in the pre-polymerization system to synthesize the imprinted polymers. Molecular modeling gives information about molecular interactions and the Gibbs free energies of the pre-polymerization complex. Based on the computational study, andrographolide, methacrylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) were used as the template, functional monomer, and cross-linker, respectively at the 1:3:20 ratios. The MIPs were characterized by kinetic study and imprinting factor. The binding parameters for the recognition of andrographolide were studied using Langmuir, Freundlich and Langmuir-Freundlich adsorption isotherm models. Andrographolide MIP contains the maximum number of binding sites with the adsorption capacity of 149.59 μg/g. The SPME experimental data best fit with Langmuir-Freundlich isotherm model with the R2 value of 0.997. This research shows that the MIPs prepared by precipitation polymerization gives a good extraction capability using SPME method.

scholarly journals Green multi-functional monomer based ion imprinted polymers for selective removal of copper ions from aqueous solution

2019 ◽  
Vol 541 ◽  
pp. 376-386 ◽  
Author(s):  
Liyan Wang ◽  
Jinhua Li ◽  
Jianan Wang ◽  
Xiaotong Guo ◽  
Xiaoyan Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Copper Ions ◽  
Selective Removal ◽  
Functional Monomer ◽  
Imprinted Polymers ◽  
Ion Imprinted ◽  
Ion Imprinted Polymers

Poly(methyl methacrylate)/Graphene Oxide Nanocomposites by a Precipitation Polymerization Process and Their Dielectric and Rheological Characterization

2014 ◽  
Vol 47 (6) ◽  
pp. 2149-2155 ◽  
Author(s):  
Jean-Michel Thomassin ◽  
Milana Trifkovic ◽  
Walid Alkarmo ◽  
Christophe Detrembleur ◽  
Christine Jérôme ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Methyl Methacrylate ◽  
Precipitation Polymerization ◽  
Polymerization Process ◽  
Rheological Characterization ◽  
Poly Methyl Methacrylate

Uniformly-sized, molecularly imprinted polymers for nicotine by precipitation polymerization

2006 ◽  
Vol 1134 (1-2) ◽  
pp. 88-94 ◽  
Author(s):  
Haruyo Sambe ◽  
Kaori Hoshina ◽  
Ruin Moaddel ◽  
Irving W. Wainer ◽  
Jun Haginaka
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Precipitation Polymerization ◽  
Molecularly Imprinted ◽  
Imprinted Polymers
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