Ficoll Activation of a Protein Essential for Maturation of the Free-Living Nematode Caenorhabditis briggsae.

1966 ◽  
Vol 121 (2) ◽  
pp. 390-393 ◽  
Author(s):  
E. J. Buecher ◽  
E. Hansen ◽  
E. A. Yarwood
Keyword(s):  
Caenorhabditis Briggsae ◽  
Free Living ◽  
Free Living Nematode

scholarly journals Cold survival and its molecular mechanisms in a locally adapted nematode population

2021 ◽  
Author(s):  
Wenke Wang ◽  
Anna G. Flury ◽  
Jennifer L. Garrison ◽  
Rachel B. Brem
Keyword(s):  
Molecular Mechanisms ◽  
Mutational Analysis ◽  
Transcriptional Profiling ◽  
Expression Patterns ◽  
Evolutionary Model ◽  
Caenorhabditis Briggsae ◽  
Free Living ◽  
Free Living Nematode ◽  
In The Wild ◽  
Shed Light

Since Darwin, evolutionary biologists have sought to understand the drivers and mechanisms of natural trait diversity. The field advances toward this goal with the discovery of phenotypes that vary in the wild, their relationship to ecology, and their underlying genes. Here, we established resistance to extreme low temperature in the free-living nematode Caenorhabditis briggsae as an ecological and evolutionary model system. We found that C. briggsae strains of temperate origin were strikingly more cold-resistant than those isolated from tropical localities. Transcriptional profiling revealed expression patterns unique to the resistant temperate ecotype, including dozens of genes expressed at high levels even after multiple days of cold-induced physiological slowdown. Mutational analysis validated a role in cold resistance for seven such genes. As the temperate C. briggsae population likely diverged only ~700 years ago from tropical ancestors, our findings highlight a candidate case of very rapid, robust, and genetically complex adaptation, and shed light on the mechanisms at play.

Freeze-thaw survival of the free-living nematode Caenorhabditis briggsae

Cryobiology ◽  
1975 ◽  
Vol 12 (5) ◽  
pp. 497-505 ◽  
Author(s):  
M. Haight ◽  
J. Frim ◽  
J. Pasternak ◽  
H. Frey
Keyword(s):  
Caenorhabditis Briggsae ◽  
Free Living ◽  
Freeze Thaw ◽  
Free Living Nematode

scholarly journals Nematode Hsp90: highly conserved but functionally diverse

Parasitology ◽  
2014 ◽  
Vol 141 (9) ◽  
pp. 1203-1215 ◽  
Author(s):  
VICTORIA GILLAN ◽  
EILEEN DEVANEY
Keyword(s):  
Life Cycle ◽  
Heat Shock Protein 90 ◽  
Ecological Niches ◽  
Actual Number ◽  
Host Organism ◽  
Free Living ◽  
Parasitic Species ◽  
Free Living Nematode ◽  
Functionally Diverse

SUMMARYNematodes are amongst the most successful and abundant organisms on the planet with approximately 30 000 species described, although the actual number of species is estimated to be one million or more. Despite sharing a relatively simple and invariant body plan, there is considerable diversity within the phylum. Nematodes have evolved to colonize most ecological niches, and can be free-living or can parasitize plants or animals to the detriment of the host organism. In this review we consider the role of heat shock protein 90 (Hsp90) in the nematode life cycle. We describe studies on Hsp90 in the free-living nematode Caenorhabditis elegans and comparative work on the parasitic species Brugia pahangi, and consider whether a dependence upon Hsp90 can be exploited for the control of parasitic species.

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