Serum Lipoproteins in Experimental Diabetes. I. Serum Lipoprotein Pattern of Normal and Depancreatized Dogs.

1954 ◽  
Vol 85 (4) ◽  
pp. 609-613 ◽  
Author(s):  
A. Fasoli ◽  
E. B. Magid ◽  
M. D. Glassman ◽  
P. P. Foa
1961 ◽  
Vol 201 (1) ◽  
pp. 27-28 ◽  
Author(s):  
Samuel Gordon ◽  
Walter P. Cekleniak

Gerbils on a 1% cholesterol supplemented diet develop a peak hypercholesteremia within a week, which subsequently decreases after 30–60 days to an elevated plateau. No evidence of atheroma formation could be observed for periods up to 6 months. Maximum concentration of serum lipoproteins was found in the Sf 35–100 and 100–400 classes, with relatively low levels in the Sf 0–10, 10–20, and 20–35 classes. After 90 days, however, a reversal of the above pattern was observed.


1971 ◽  
Vol 17 (5) ◽  
pp. 427-429 ◽  
Author(s):  
N M Papadopoulos ◽  
J A Kintzios

Abstract A previously reported agarose gel electrophoretic technique for the determination of serum lipoprotein patterns has been modified for analysis of a large number of samples for screening and epidemiological purposes. In addition, we demonstrate the varieties of lipoprotein patterns that can clearly be distinguished and visually evaluated for practical applications in the clinical laboratory.


1983 ◽  
Vol 29 (5) ◽  
pp. 768-773 ◽  
Author(s):  
M Okazaki ◽  
H Itakura ◽  
K Shiraishi ◽  
I Hara

Abstract An HPLC method [J. Biochem. (Tokyo) 91:1381, 1982] was used for evaluating serum lipoproteins, with on-line monitoring of either cholesterol or phospholipids. Five well-distinguished lipoprotein fractions were observed, based on their particle sizes. Serum of 15 normal persons, 12 subjects with various types of hyperlipidemia, 20 patients with various liver diseases, and two cases of familial LCAT deficiency were examined and the results compared with those by a sequential ultracentrifugal floatation technique. In the normal group, the amounts of fractions 2, 3, and 4 by the HPLC method correlated well with concentrations of the LDL, HDL2, and HDL3 fractions as measured by the ultracentrifugal method, respectively. In the hyperlipidemic group, similar good correlations were observed between fractions 1, 2, 3, 4 and chylomicrons + VLDL, LDL, HDL2, and HDL3 fractions, respectively. For those with liver diseases or LCAT deficiency, the corresponding fractions correlated less well, and characteristically the elution profile of lipoproteins in these groups showed heterogeneity of particle size within each lipoprotein density class, especially in LDL and HDL2.


Author(s):  
P. Mondola ◽  
F. Santangelo ◽  
M. Santillo ◽  
A. Belfiore ◽  
L. Avallone ◽  
...  

1960 ◽  
Vol 15 (1) ◽  
pp. 145-148 ◽  
Author(s):  
Arthur R. Tamplin ◽  
Robert K. Tandy

Age and sex trends in individual and population statistics of the low density serum lipoproteins are presented and discussed. The data disclose a lack of conformity between populations which reasonably could be considered comparable random population samples. The data also indicate a metabolic independence of the sf 0 – 20 and the sf 20 – 400 lipoprotein classes and the suggestion is introduced that this is due to a metabolic independence of cholesterol and triglycerides. Submitted on April 13, 1959


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