Serum lipoprotein pattern of the hypercholesteremic gerbil

1961 ◽  
Vol 201 (1) ◽  
pp. 27-28 ◽  
Author(s):  
Samuel Gordon ◽  
Walter P. Cekleniak
Keyword(s):  
Maximum Concentration ◽  
Serum Lipoprotein ◽  
Serum Lipoproteins ◽  
Low Levels ◽  
Lipoprotein Pattern

Gerbils on a 1% cholesterol supplemented diet develop a peak hypercholesteremia within a week, which subsequently decreases after 30–60 days to an elevated plateau. No evidence of atheroma formation could be observed for periods up to 6 months. Maximum concentration of serum lipoproteins was found in the Sf 35–100 and 100–400 classes, with relatively low levels in the Sf 0–10, 10–20, and 20–35 classes. After 90 days, however, a reversal of the above pattern was observed.

Varieties of Human Serum Lipoprotein Pattern: Evaluation by Agarose Gel Electrophoresis

1971 ◽  
Vol 17 (5) ◽  
pp. 427-429 ◽  
Author(s):  
N M Papadopoulos ◽  
J A Kintzios
Keyword(s):  
Human Serum ◽  
Gel Electrophoresis ◽  
Clinical Laboratory ◽  
Serum Lipoprotein ◽  
Agarose Gel ◽  
Agarose Gel Electrophoresis ◽  
Practical Applications ◽  
Electrophoretic Technique ◽  
Lipoprotein Pattern

Abstract A previously reported agarose gel electrophoretic technique for the determination of serum lipoprotein patterns has been modified for analysis of a large number of samples for screening and epidemiological purposes. In addition, we demonstrate the varieties of lipoprotein patterns that can clearly be distinguished and visually evaluated for practical applications in the clinical laboratory.

Serum lipoprotein measurement--liquid chromatography and sequential floatation (ultracentrifugation) compared.

1983 ◽  
Vol 29 (5) ◽  
pp. 768-773 ◽  
Author(s):  
M Okazaki ◽  
H Itakura ◽  
K Shiraishi ◽  
I Hara
Keyword(s):  
Liver Diseases ◽  
Hplc Method ◽  
Serum Lipoprotein ◽  
Particle Sizes ◽  
Elution Profile ◽  
Serum Lipoproteins ◽  
On Line ◽  
Lcat Deficiency ◽  
Similar Good ◽  
Lipoprotein Measurement

Abstract An HPLC method [J. Biochem. (Tokyo) 91:1381, 1982] was used for evaluating serum lipoproteins, with on-line monitoring of either cholesterol or phospholipids. Five well-distinguished lipoprotein fractions were observed, based on their particle sizes. Serum of 15 normal persons, 12 subjects with various types of hyperlipidemia, 20 patients with various liver diseases, and two cases of familial LCAT deficiency were examined and the results compared with those by a sequential ultracentrifugal floatation technique. In the normal group, the amounts of fractions 2, 3, and 4 by the HPLC method correlated well with concentrations of the LDL, HDL2, and HDL3 fractions as measured by the ultracentrifugal method, respectively. In the hyperlipidemic group, similar good correlations were observed between fractions 1, 2, 3, 4 and chylomicrons + VLDL, LDL, HDL2, and HDL3 fractions, respectively. For those with liver diseases or LCAT deficiency, the corresponding fractions correlated less well, and characteristically the elution profile of lipoproteins in these groups showed heterogeneity of particle size within each lipoprotein density class, especially in LDL and HDL2.

Spatial anomalies of uranium background levels in groundwater of Lower Saxony

2020 ◽  
Author(s):  
Roland Stumpf ◽  
Dörte Budziak ◽  
Nico Deus ◽  
Jörg Elbracht
Keyword(s):  
Maximum Concentration ◽  
Hydrological Cycle ◽  
Tap Water ◽  
Daily Intake ◽  
World Health ◽  
Chemical Toxicity ◽  
Lower Saxony ◽  
Rock Interaction ◽  
Background Values ◽  
Low Levels

<p><span>Uranium is a trace metal yielding an average concentration in the Earth’s crust of about 2 to 4 mg/kg, and it occurs naturally in low levels in rock, soil, and water. Although widely known for its radioactive properties, at low levels dissolved uranium is more harmful by its chemical toxicity. The World Health Organisation (WHO) recommends a maximum concentration of 30 µg/l uranium in tap water, as well as a tolerable daily intake limit of 0.6 µg/kg body weight. Since 2011, tap water in Germany must not exceed uranium concentrations of 10 µg/l. </span></p><p><span>The uranium budget of the groundwater in Lower Saxony comprises mainly of geogenic input through water-rock interaction along the hydrological cycle and within the respective hydrogeological units, and possibly through century-old mining activities, and more recently the use of uranium bearing mineral fertilisers in farming. While the vast majority of uranium concentrations are significantly below 10 µg/l with many values below detection limit, some detached areas display elevated uranium with one confined maximum concentration of 124 µg/l. In order to determine uranium background values, statistical analyses accounted for hydrogeological units of the aquifer, land use, and well depths. Anomalous peak concentrations are unlikely to be a result of variations in geogenic background values alone and require further investigations. A possible rise of uranium concentrations caused by a downward shifting redox front, as proposed in other regions in Northern Germany, is yet to be identified in Lower Saxony.</span></p>

The serum lipoprotein pattern of water buffalo (Bubalus bubalis)

1987 ◽  
Vol 88 (2) ◽  
pp. 395-398
Author(s):  
P. Mondola ◽  
F. Santangelo ◽  
M. Santillo ◽  
A. Belfiore ◽  
L. Avallone ◽  
...  
Keyword(s):  
Water Buffalo ◽  
Bubalus Bubalis ◽  
Serum Lipoprotein ◽  
Lipoprotein Pattern

Serum lipoprotein statistics in populations and individuals

1960 ◽  
Vol 15 (1) ◽  
pp. 145-148 ◽  
Author(s):  
Arthur R. Tamplin ◽  
Robert K. Tandy
Keyword(s):  
Serum Lipoprotein ◽  
Low Density ◽  
Serum Lipoproteins ◽  
Population Statistics ◽  
Age And Sex

Age and sex trends in individual and population statistics of the low density serum lipoproteins are presented and discussed. The data disclose a lack of conformity between populations which reasonably could be considered comparable random population samples. The data also indicate a metabolic independence of the sf 0 – 20 and the sf 20 – 400 lipoprotein classes and the suggestion is introduced that this is due to a metabolic independence of cholesterol and triglycerides. Submitted on April 13, 1959

Serum lipoprotein stimulation of lipolysis and its relevance to free fatty acid development in bovine milk

1983 ◽  
Vol 50 (3) ◽  
pp. 309-319 ◽  
Author(s):  
Malcolm Anderson ◽  
Eric C. Needs
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Blood Serum ◽  
Milk Fat ◽  
Bovine Milk ◽  
Serum Lipoprotein ◽  
Serum Lipoproteins ◽  
Cell Counts ◽  
Highly Correlated ◽  
And Control

SummaryThe role of blood serum lipoproteins in stimulating milk lipolysis was investigated by adding blood serum and heparin to the milk of normal cows and cows in which elevated somatic cell counts were induced by intramammary infusion of Escherichia coli endotoxin and Staphylococcus aureus. There was considerable variation between individual milks in the extent to which lipolysis was stimulated. In some milks there was almost no response. For values obtained from 29 cows during the first 6 months of lactation a relationship was observed between free fatty acid (FFA) levels in the untreated and serum-stimulated samples (r = 0·776). FFA values were higher after 18 h at 4 °C in milks from infused quarters than in those from control quarters, but this difference was not entirely due to higher values from the infused quarters at 0 h. Both blood serum and heparin stimulated lipolysis in high cell count milks and control milks. The response to heparin was greater than that to blood serum, but the response to both was highly correlated with FFA levels in the untreated milks. There were no differences in the ability of skim-milks prepared from infused and control quarters to promote lipolysis in recombined milks containing sterilized homogenized milk fat globules as a source of substrate. Incubation of blood serum with 2 μg/ml trypsin for 1 h at 37 °C reduced the ability of the serum to promote lipolysis. The importance of lipase activation by blood serum lipoproteins in relation to milk lipolysis is discussed.

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