Synthesis of 4-aryl-2-Thioxo-3,4-Dihydropyrimidines Using a Three-Component Reaction of Meldrum's Acid with Arylaldehydes and Acetylthiourea
2018 ◽
Vol 42
(6)
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pp. 326-328
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Keyword(s):
One Pot
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A one-pot method for the preparation of new 4-aryl-2-thioxo-3,4-dihydropyrimidines via a three-component reaction of Meldrum's acid with arylaldehydes and acetylthiourea in the presence of p-toluenesulfonic acid as catalyst in CH3CN under reflux is reported.