A highly efficient protocol for the synthesis of new 3-(α-aroylamido)-4-hydroxycoumarin derivatives using SnCl2–SiO2 nanoparticles under solvent-free conditions

2017 ◽  
Vol 41 (6) ◽  
pp. 321-324 ◽  
Author(s):  
Mona Arfavi-Safari ◽  
Hossein Anaraki-Ardakani ◽  
Rashid Badri ◽  
Elham Tahanpesar
Keyword(s):  
Sio2 Nanoparticles ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Atom Economy ◽  
Reaction Conditions ◽  
Chromatographic Separations ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Simple Protocol

An efficient and simple protocol for the synthesis of the title compounds is described via a one-pot, three-component reaction of 4-hydroxycoumarin, aryl glyoxals and amides, using SnCl2-SiO2 nanoparticles as a heterogeneous catalyst under solvent-free conditions. The advantages of this synthesis include excellent yields, mild reaction conditions, atom economy, a reusable catalyst and no need for chromatographic separations.

Solvent-free Synthesis of 1,2-Disubstituted Derivatives of 1,2- Dihydroisoquinoline, 1,2-Dihydroquinoline and 1,2-Dihydropyridine

2013 ◽  
Vol 68 (7) ◽  
pp. 818-822 ◽  
Author(s):  
Rahimeh Hajinasiri ◽  
Sobhan Rezayati
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
Reaction Conditions ◽  
One Pot ◽  
Efficient Approach ◽  
Dialkyl Acetylenedicarboxylates ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Derivatives Of ◽  
Solvent Free Synthesis

A one-pot and efficient approach to the synthesis of dialkyl 2-[1-[(alkoxycarbonyl)anilino]-2(1H)- (isoquinolin-2-yl) (or -quinolin-1-yl or -pyridin-1-yl)]-2-butenedioates is described. This method involves a three-component reaction between isoquinoline, quinoline or pyridine, dialkyl acetylenedicarboxylates and N-phenylcarbamates under solvent-free conditions, without using any catalyst and at room temperature. The mild reaction conditions and good yields of the products exhibit the synthetic advantage of this method.

scholarly journals Fe3O4@urea/HITh-SO3H as an efficient and reusable catalyst for the solvent-free synthesis of 7-aryl-8H-benzo[h]indeno[1,2-b]quinoline-8-one and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine derivatives

2020 ◽  
Vol 18 (1) ◽  
pp. 648-662
Author(s):  
Shenghao Jiang ◽  
Macheng Shen ◽  
Fatima Rashid Sheykhahmad
Keyword(s):  
Electron Microscopy ◽  
Reaction Times ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Pyrimidine Derivatives ◽  
Magnetic Nanocatalyst ◽  
One Pot ◽  
X Ray ◽  
Solvent Free Conditions ◽  
Three Component Reaction

AbstractIn this study, Fe3O4@urea/HITh-SO3H MNPs as a new, efficient, and recyclable solid acid magnetic nanocatalyst was synthesized and characterized using various methods including Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometry, energy-dispersive X-ray spectroscopy, and X-ray powder diffraction. After the characterization of this new magnetic nanocatalyst, it was efficiently utilized for the promotion of the one-pot synthesis of 7-aryl-8H-benzo[h]indeno[1,2-b]quinoline-8-one and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine derivatives via three-component reaction of the 1,3-indanedione, aldehyde, and 1-naphthylamine/1,3-dimethyl-6-aminouracil under solvent-free conditions at 80°C. The procedure gave the desired heterocyclic structures in high-to-excellent yields and short reaction times. Also because of the magnetic nature of the nanocatalyst, it can be separated with an external magnetic field and reused at least six runs without any considerable decrease in the catalytic behavior.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

ChemInform Abstract: TiO2 as a Reusable Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions.

ChemInform ◽  
2010 ◽  
Vol 41 (26) ◽  
pp. no-no
Author(s):  
Mohammad Zaman Kassaee ◽  
Hassan Masrouri ◽  
Farnaz Movahedi ◽  
Reza Mohammadi
Keyword(s):  
Solvent Free ◽  
Reusable Catalyst ◽  
One Pot ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
The One

scholarly journals Silica sulfuric acid: a reusable solid catalyst for one pot synthesis of densely substituted pyrrole-fused isocoumarins under solvent-free conditions

2013 ◽  
Vol 9 ◽  
pp. 2344-2353 ◽  
Author(s):  
Sudipta Pathak ◽  
Kamalesh Debnath ◽  
Animesh Pramanik
Keyword(s):  
Sulfuric Acid ◽  
Low Cost ◽  
Solvent Free ◽  
Primary Amines ◽  
Solid Catalyst ◽  
Silica Sulfuric Acid ◽  
Reaction Conditions ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Solvent Free Reaction

A convenient and efficient methodology for the synthesis of densely substituted pyrrole-fused isocoumarins, which employs solid-supported silica sulfuric acid (SSA) as catalyst, has been developed. When the mixture of ninhydrin adducts of acetylacetone/ethyl acetoacetate and primary amines was heated on the solid surface of SSA under solvent-free conditions, the pyrrole-fused isocoumarins were formed in good yields. This synthetic method has several advantages such as the employment of solvent-free reaction conditions without the use of any toxic reagents and metal catalysts, the ease of product isolation, the use of a recyclable catalyst, the low cost, the easy availability of the starting materials, and the excellent yields of products.

scholarly journals One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by SO3H@imineZCMNPs as a novel, efficient and reusable acidic nanocatalyst under solvent-free conditions

RSC Advances ◽  
2018 ◽  
Vol 8 (70) ◽  
pp. 40243-40251 ◽  
Author(s):  
Esmayeel Abbaspour-Gilandeh ◽  
Asieh Yahyazadeh ◽  
Mehraneh Aghaei-Hashjin
Keyword(s):  
Solvent Free ◽  
Magnetic Nanocatalyst ◽  
One Pot ◽  
Environment Friendly ◽  
Novel Environment ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Three Component Reaction

The synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives was accomplished via a three-component reaction in the presence of SO3H@imineZCMNPs as a novel, environment friendly, and reusable heterogeneous magnetic nanocatalyst under solvent-free conditions at 90 °C.

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