Histamine H3 Receptor Antagonists for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Momoko Kubo; Taro Kishi; Shinji Matsunaga; Nakao Iwata

doi:10.3233/jad-150393

Histamine H3 Receptor Antagonists for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Journal of Alzheimer s Disease ◽

10.3233/jad-150393 ◽

2015 ◽

Vol 48 (3) ◽

pp. 667-671 ◽

Cited By ~ 13

Author(s):

Momoko Kubo ◽

Taro Kishi ◽

Shinji Matsunaga ◽

Nakao Iwata

Keyword(s):

Systematic Review ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Meta Analysis ◽

Controlled Trials ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Computational analysis of novel drugs designed for use as acetylcholinesterase inhibitors and histamine H3 receptor antagonists for Alzheimer's disease by docking, scoring and de novo evolution

Molecular Medicine Reports ◽

10.3892/mmr.2012.757 ◽

2012 ◽

Vol 5 (4) ◽

pp. 1043-1048 ◽

Cited By ~ 12

Author(s):

PO-YUAN CHEN ◽

CHING-TSAN TSAI ◽

CHE-YEN OU ◽

WEI-TSE HSU ◽

MIEN-DE JHUO ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Computational Analysis ◽

De Novo ◽

Acetylcholinesterase Inhibitors ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Novel Drugs ◽

Histamine H3

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Histamine H3 receptor antagonists/inverse agonists on cognitive and motor processes: relevance to Alzheimer's disease, ADHD, schizophrenia, and drug abuse

Frontiers in Systems Neuroscience ◽

10.3389/fnsys.2012.00072 ◽

2012 ◽

Vol 6 ◽

Cited By ~ 32

Author(s):

Divya Vohora ◽

Malay Bhowmik

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Drug Abuse ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

Inverse Agonists ◽

Motor Processes ◽

H3 Receptor ◽

Histamine H3

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In-vivo histamine H3 receptor antagonism activates cellular signaling suggestive of symptomatic and disease modifying efficacy in Alzheimer’s disease

Neuropharmacology ◽

10.1016/j.neuropharm.2010.10.026 ◽

2011 ◽

Vol 60 (2-3) ◽

pp. 460-466 ◽

Cited By ~ 42

Author(s):

R. Scott Bitner ◽

Stella Markosyan ◽

Arthur L. Nikkel ◽

Jorge D. Brioni

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cellular Signaling ◽

Receptor Antagonism ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Disease Modifying ◽

Histamine H3

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Exercise interventions in Alzheimer’s disease: A systematic review and meta-analysis of randomized controlled trials

Ageing Research Reviews ◽

10.1016/j.arr.2021.101479 ◽

2021 ◽

pp. 101479

Author(s):

Susana López-Ortiz ◽

Pedro L. Valenzuela ◽

María M. Seisdedos ◽

Javier S. Morales ◽

Tomás Vega ◽

...

Keyword(s):

Systematic Review ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Randomized Controlled Trials ◽

Meta Analysis ◽

Controlled Trials ◽

Exercise Interventions ◽

Randomized Controlled

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Corrigendum to “Search for new multi-target compounds against Alzheimer’s disease among histamine H3 receptor ligands” [Eur. J. Med. Chem. 185 (2020) 111785]

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112611 ◽

2020 ◽

Vol 205 ◽

pp. 112611

Author(s):

Marek Bajda ◽

Dorota Łażewska ◽

Justyna Godyń ◽

Paula Zaręba ◽

Kamil Kuder ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b00937 ◽

2019 ◽

Vol 62 (24) ◽

pp. 11416-11422 ◽

Cited By ~ 11

Author(s):

Rim Malek ◽

Raquel L. Arribas ◽

Alejandra Palomino-Antolin ◽

Perle Totoson ◽

Celine Demougeot ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Calcium Channels ◽

Small Molecules ◽

Cholinesterase Inhibition ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Disease Therapy ◽

Histamine H3

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Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112743 ◽

2020 ◽

Vol 207 ◽

pp. 112743

Author(s):

Dorota Łażewska ◽

Marek Bajda ◽

Maria Kaleta ◽

Paula Zaręba ◽

Agata Doroz-Płonka ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Rational Design ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Search for new multi-target compounds against Alzheimer’s disease among histamine H3 receptor ligands

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111785 ◽

2020 ◽

Vol 185 ◽

pp. 111785 ◽

Cited By ~ 9

Author(s):

Marek Bajda ◽

Dorota Łażewska ◽

Justyna Godyń ◽

Paula Zaręba ◽

Kamil Kuder ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Receptor Ligands ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

Histamine H3

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Cognitive outcomes of anti‐amyloid‐β monoclonal antibodies in patients with Alzheimer's disease: A systematic review and meta‐analysis of randomized controlled trials

Alzheimer s & Dementia ◽

10.1002/alz.057778 ◽

2021 ◽

Vol 17 (S9) ◽

Author(s):

Paulo Eduardo Lahoz Fernandez ◽

Guilherme Diogo Silva

Keyword(s):

Systematic Review ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Monoclonal Antibodies ◽

Randomized Controlled Trials ◽

Meta Analysis ◽

Amyloid Β ◽

Cognitive Outcomes ◽

Controlled Trials ◽

Randomized Controlled

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Ginkgo Biloba for Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Current Topics in Medicinal Chemistry ◽

10.2174/1568026615666150813143520 ◽

2015 ◽

Vol 16 (5) ◽

pp. 520-528 ◽

Cited By ~ 47

Author(s):

Guoyan Yang ◽

Yuyi Wang ◽

Jin Sun ◽

Kang Zhang ◽

Jianping Liu

Keyword(s):

Systematic Review ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Randomized Controlled Trials ◽

Ginkgo Biloba ◽

Meta Analysis ◽

Controlled Trials ◽

Randomized Controlled

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