A Systematic Review and Case Series of Ziprasidone for Psychosis in Parkinson’s Disease

Introduction: Parkinson’s disease is a progressive and degenerative pathology that causes several motor impairments in gait. Aquatic physiotherapy has become an alternative, as it allows the training of gait, balance and muscle relaxation in a safe environment due to the physical properties of water. Objective: to verify the main effects of aquatic physiotherapy on gait rehabilitation in patients with Parkinson’s disease. Study design: This is a systematic review. Methodology: The research was carried out in four distinct stages. Being carried out in the following databases EBSCO, Pubmed, PEDro, Science Direct and MEDLINE; obeying the following inclusion criteria: individuals diagnosed with idiopathic Parkinson’s disease; who underwent aquatic physiotherapy with or without a control group and the main outcome was the improvement in gait performance. Case studies, case series, monograph, dissertation and articles without full access were excluded. The following keywords were used in the research field (“hydrotherapy” OR “aquatic exercise OR aquatic therapy”) AND Parkinson’s disease AND Gait. Results: Ten articles with good to regular methodological quality were included. Most of the results of the study were functional mobility, balance, pathology progression and gait parameters. Conclusion: it was observed that aquatic physiotherapy promoted good results in gait performance, mainly in balance, functional mobility and decreased motor signals, however there is still evidence about gait parameters.

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Othello syndrome in Parkinson’s disease: a systematic review and report of a case series

Neurological Sciences ◽

10.1007/s10072-021-05249-4 ◽

2021 ◽

Author(s):

Giovanna De Michele ◽

Gianluigi Rosario Palmieri ◽

Chiara Pane ◽

Carmen Diletta Paola Dello Iacovo ◽

Sandra Perillo ◽

...

Keyword(s):

Systematic Review ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Single Case ◽

Case Reports ◽

Case Series ◽

Visual Hallucinations ◽

Levodopa Dose ◽

Cross Sectional ◽

Pubmed Database

Abstract Introduction Psychosis in Parkinson’s disease (PD) is common and consists of hallucinations, illusions, and delusions. Among the latter, delusional jealousy, also named Othello syndrome (OS), might impair the quality of life of both patients and their partners. We aimed to perform a systematic review and report a series of PD patients presenting with OS. Methods A systematic review research was performed in PubMed database, excluding non-English articles, single case reports, reviews and neuropathology articles, comments, and articles concerning OS associated with deep brain stimulation (DBS) and levodopa-carbidopa intestinal gel infusion. We also described eleven PD patients (9 M and 2 F) with OS, identified in a cohort of consecutive 153 patients, comparing them with eleven matched no OS (nOS) PD subjects taken from the same cohort. Results We included eight articles (four case series and four cross-sectional studies). OS resulted more common among males than females. We did not find higher levodopa dose and levodopa equivalent dose for dopamine agonists and for all anti-parkinsonian drugs in our OS group. In our case series, OS patients showed visual hallucinations (p=0.001) and a trend to have depression (p=0.080) more frequently than nOS ones. Conclusions OS is not a rare disorder in PD, probably due not only to abnormal dopaminergic stimulation but also to serotonergic dysfunction in biologically predisposed subjects. Visual hallucinations and other concomitant psychiatric diseases, in particular depression, might represent a risk factor for the OS development.

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Diagnosis and Treatment of Parkinson's Disease: A Systematic Review of the Literature: Evidence Report/Technology Assessment, Number 57

PsycEXTRA Dataset ◽

10.1037/e439422005-001 ◽

2003 ◽

Cited By ~ 5

Author(s):

Cindy B. Levine ◽

◽

Kyle R. Fahrbach ◽

Andrew D. Siderowf ◽

Rhonda P. Estok ◽

...

Keyword(s):

Systematic Review ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Technology Assessment ◽

Diagnosis And Treatment ◽

Review Of The Literature ◽

Literature Evidence

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Faculty Opinions recommendation of Prevalence of anxiety in Parkinson's disease: A systematic review and meta-analysis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726321810.793520444 ◽

2016 ◽

Author(s):

Joseph Jankovic ◽

Mary Ann Thenganatt

Keyword(s):

Systematic Review ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Meta Analysis

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The Profile of People with Parkinson’s Disease Included in Community Boxing Exercise Programs

Medical Sciences Forum ◽

10.3390/msf2021005005 ◽

2021 ◽

Vol 5 (1) ◽

pp. 5

Author(s):

Josefa Domingos ◽

Tamine Capato ◽

Catarina Godinho

Keyword(s):

Systematic Review ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Negative Impact ◽

Patient Characteristics ◽

Inclusion Criteria ◽

Exercise Programs

Exercise is widely recommended for people with Parkinson (PD). Boxing is a popular mode of training. However, including individuals with less favorable profiles may have a negative impact on participation. We performed a systematic review to study the patient characteristics that were included in boxing exercise programs research and reflect on the possible inclusion criteria that professionals can use for boxing exercise programs. Indications for the best profiles were limited due to the small number of studies. Boxing programs should include people with the diagnosis of PD in earlier stages, independently ambulatory, and without current severe musculoskeletal or cardiovascular conditions.

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