scholarly journals Isolated deep cerebral venous thrombosis

2020 ◽  
Vol 4 (9) ◽  
pp. 595-600
Author(s):  
T.V. Matveeva ◽  
◽  
M.M. Ibatullin ◽  
R.T. Gaifutdinov ◽  
A.Yu. Kazantsev ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Brain Lesion ◽  
Disease Onset ◽  
Connective Tissue Diseases ◽  
Pulse Therapy ◽  
Primary Diagnosis ◽  
Deep Cerebral Venous Thrombosis

Deep cerebral venous thrombosis is a rare pathology and hard to diagnose cause of the acute cerebrovascular diseases. Commonly, the veins of Galen and Rosenthal affected by the non-isolated deep cerebral venous thrombosis are described in most of the publications. The article presents a clinical case of an extremely rare isolated deep cerebral venous thrombosis in a female patient aged 31 years with a burdened obstetric history and thrombophilia. The disease onset started with increasing hypertension headache, congestive changes in the fundus, cerebellar and pyramidal signs. Magnetic resonance imaging (MRI) of the brain revealed a pattern of a multi-focal brain lesion. Thus, the primary diagnosis of «multiple sclerosis» was established, so the patient received pulse therapy. Differential diagnosis was conducted with systemic connective tissue diseases. Regression of headaches, of changes in the fundus, dynamic neuroimaging data, and the results of hematology test made it possible to diagnose «deep cerebral venous thrombosis». During the anticoagulant therapy, there was a positive dynamics: the foci significantly regressed according to MRI data, the patient became pregnant and delivered a healthy child. The article describes the characteristics of MRI images on deep cerebral venous thrombosis, which can be used to diagnose this patholo gy. KEYWORDS: deep cerebral venous thrombosis, сerebral venous sinus thrombosis, thrombophilia, coagulopathy, infertility, headache, multiple sclerosis. FOR CITATION: Matveeva T.V., Ibatullin M.M., Gaifutdinov R.T. et al. Isolated deep cerebral venous thrombosis. Russian Medical Inquiry. 2020;4(9):595–600. DOI: 10.32364/2587-6821-2020-4-9-595-600.

Scrub typhus with cerebral venous sinus thrombosis: a rare presentation

2021 ◽  
Vol 14 (4) ◽  
pp. e241401
Author(s):  
Sayonee Das ◽  
Sidhartha Chattopadhyay ◽  
Kausik Munsi ◽  
Sagar Basu
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Scrub Typhus ◽  
Sinus Thrombosis ◽  
Hormonal Contraception ◽  
Neurological Involvement ◽  
Rare Presentation ◽  
Specific Test ◽  
Satisfactory Outcome ◽  
The Brain

This is a rare presentation of scrub typhus with cerebral venous thrombosis. A 32-year-old woman presented with signs of raised intracranial tension. Examination revealed maculopapular skin rashes and an ‘eschar’ over the right thigh. Nuchal rigidity and bilateral papilloedema were found. Scrub typhus was diagnosed by the presence of IgM antibody in serum. CT scan of the brain showed cerebral oedema. MRI of the brain was normal. Magnetic resonance venography of the brain showed thrombosis of several venous sinuses. Cerebrospinal fluid analysis revealed lymphocytic pleocytosis with raised protein level. Other causes of prothrombotic states were ruled out by doing specific test results. There was no history of hormonal contraception and prolonged bed rest. A case of scrub typhus complicated with meningoencephalitis and cerebral venous thrombosis was diagnosed. She responded to treatment with doxycycline, anticoagulants, antipyrectics and intravenous saline. Early identification of such atypical neurological involvement in scrub typhus was helpful in satisfactory outcome.

scholarly journals Cerebral venous thrombosis and Covid 19: Literature review

2021 ◽  
Vol 11 (2) ◽  
pp. 57-68
Author(s):  
Carlos Alexandre Martins Zicarelli ◽  
Jonathan Vinicius Martins ◽  
Wesley Vieira Doni ◽  
Rafael Rodrigues Pinheiro dos Santos ◽  
Ana Carla Mondek Rampazzo ◽  
...  
Keyword(s):  
Literature Review ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Clinical Manifestations ◽  
Risk Of Death ◽  
Cranial Sinus Thrombosis ◽  
Stent Retrievers ◽  
Low Incidence

Introduction: Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) was first detected in December 2019 in the city of Wuhan, China, and has since taken on worldwide proportions. It is known that individuals with Coronavirus disease-19 (COVID-19) have systemic clinical manifestations. Among the multisystemic effects, cerebral venous thrombosis (CVT) is responsible for high mortality rates. In this sense, understanding the association between CVT and SARS-CoV-2 infection directly impacts the disease's morbidity and mortality. Methodology: Literature review in the PubMed and Embase databases, with the following search terms: “COVID-19”, “SARS-CoV-2”, “Venous thromboembolism”, “Thrombosis”, “Cerebral Venous Thrombosis”, “Intracranial Sinus Thrombosis” and “Cranial Sinus Thrombosis”. The selected articles were written in English, which addressed the various aspects of COVID-19. Results and discussion: CVT are a rare complication of COVID-19, with an incidence between 0.02 to 1% of hospitalized patients. However, it can reach about 75% of mortality in affected individuals. Pathophysiology seems to be associated with the state of hypercoagulability and the systemic inflammatory process resulting from viral infection. Thus, recent studies show a consensus on the early anticoagulation of patients affected by the virus, to reduce mortality in these cases. However, the differences between the types of anticoagulation, Low Molecular Weight Heparin (LMWH), Unfractionated Heparin (UFH), Dabigatran have not yet been well established, although there is a predilection for the use of LMWH. Also, thrombectomy is a therapeutic intervention option that should be evaluated, due to the risk of additional endothelial injury from the use of stent retrievers. Conclusion: Although it has a relatively low incidence, CVT aggravates the condition and increases the risk of death for patients with COVID-19. Because of this, early diagnosis and evaluation of therapeutic options for CVT are essential for the development of clinical management.

Deep cerebral venous thrombosis during pregnancy

2014 ◽  
Vol 29 (1) ◽  
pp. 52-53
Author(s):  
Abdullah Hamid Feroze ◽  
Aditya Mantha ◽  
Omar Choudhri
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Deep Cerebral Venous Thrombosis

Cerebral venous thrombosis in four patients with multiple sclerosis

2003 ◽  
Vol 10 (1) ◽  
pp. 63-66 ◽  
Author(s):  
N. Vandenberghe ◽  
M. Debouverie ◽  
R. Anxionnat ◽  
P. Clavelou ◽  
S. Bouly ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis

Transitory sleep spindles impairment in deep cerebral venous thrombosis

2005 ◽  
Vol 35 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Andrea O. Rossetti ◽  
Malin Maeder-Ingvar ◽  
Marc D. Reichhart ◽  
Paul-André Despland ◽  
Julien Bogousslavsky
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Sleep Spindles ◽  
Deep Cerebral Venous Thrombosis

scholarly journals Risk factors and diagnosis of cerebral venous thrombosis: Data from a cohort of 45 Romanian patients

2014 ◽  
Vol 60 (5) ◽  
pp. 207-214
Author(s):  
Rodica Bălaşa ◽  
M Daboczi ◽  
Oana Costache ◽  
Smaranda Maier ◽  
Z Bajko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thrombosis ◽  
Brain Imaging ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Demographic Data ◽  
Brain Mri ◽  
Clinical Aspects ◽  
Initial Symptom ◽  
Clinical Criteria

Abstract Cerebral venous thrombosis (CVT) represents 1% of the total stroke pathology but is a real challenge both regarding the diagnosis and the treatment. Objective: Evaluate different etiological, demographical, clinical, imaging and therapeutic aspects of CVT. Material: Prospective study during 4 years. From the total 3658 patients hospitalized with acute stroke, 45 (1.23%) had CVT. For each patient, were recorded: demographic data, symptom of onset, type of onset, daily habits, medical history, neurological examination, brain imaging (CT and MRI with venography). Statistical analysis: data are presented as mean and SD and Student t test was applied. Results: Mean age was 44.07± 23,12 years; female: male ratio 2.21:1. The most frequent type of onset was acute (77.78%). Headache was found in 80% of cases as initial symptom, followed by neurological focal deficits. As risk factors, thrombophilia was found most often (59.5%), followed by local infections. No risk factors were found in 17.8% of cases. The brain imaging was positive in 29 patients. In 16 cases, the imaging workout was negative and the diagnosis consisted of clinical criteria, risk factors, response to heparin treatment. Conclusions: CVT is a rare pathology that affects mainly young women and that needs a complex diagnostic evaluation. The patient prototype diagnosed with CVT in our region: female of 44 years old, with an intense acute headache, with MRI showing direct signs of transverse sinus thrombosis, with a thrombophilic state and good response to anticoagulants. Brain MRI is the imaging investigation required but clinical aspects play a decisive role.

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