Development of new drug formulations: cetirizine-polymers nanoparticles

Recent advances in nanotechnology, including modern enabling techniques that can improve synthetic preparation and drug formulations, have opened up new frontiers in nanomedicine with the development of nanoscale carriers and assemblies. The use of delivery platforms has attracted attention over the past decade as researchers shift their focus away from the development of new drug candidates, and toward new means with which to deliver therapeutic and/or diagnostic agents. This work will explore a transdisciplinary approach for the production of a number of nanomaterials, nanocomplexes and nanobubbles and their application in a variety of potential biological and theranostic protocols. Particular attention will be paid to nanobubbles, stimuli responsive nanoparticles and cyclodextrin grafted nanosystems produced under non-conventional conditions, such as microwave and ultrasound irradiation. Besides nanoparticles preparation, ultrasound can also act as an enabling technology when activating sensitive nanobubbles and nanoparticles.

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New Drug Formulations and Their Respective Generic Entry Dates

Journal of Managed Care & Specialty Pharmacy ◽

10.18553/jmcp.2019.25.2.218 ◽

2019 ◽

Vol 25 (2) ◽

pp. 218-224 ◽

Cited By ~ 1

Author(s):

Reed F. Beall ◽

Aaron S. Kesselheim ◽

Ameet Sarpatwari

Keyword(s):

Drug Formulations ◽

Generic Entry ◽

New Drug

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New Drug Formulations Offer Hope for Easing Global Burden of Malaria

JAMA ◽

10.1001/jama.295.5.485 ◽

2006 ◽

Vol 295 (5) ◽

pp. 485

Keyword(s):

Global Burden ◽

Drug Formulations ◽

New Drug

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A review on efficacy of Cissus quadrangularis in pharmacological mechanisms

International Journal of Clinical Microbiology and Biochemical Technology ◽

10.29328/journal.ijcmbt.1001016 ◽

2020 ◽

Vol 3 (1) ◽

pp. 049-053

Author(s):

Zaki Sadiya ◽

Malathi R ◽

Latha V ◽

Sibi G

Keyword(s):

Systematic Review ◽

Bone Turnover ◽

Rich Source ◽

Drug Formulations ◽

New Drug ◽

Cissus Quadrangularis ◽

The World ◽

Anti Oxidant ◽

Anti Inflammatory

Cissus quadrangularis a succulent vine belongs to Vitaceae family is widely distributed throughout tropical and subtropical regions of the world and used frequently to various disorders. The plant has been reported to contain flavonoids, triterpenoids, phytosterols, glycosides and rich source of calcium. This study aims to bring a systematic review of C. quadrangularis in various pharmacological mechanisms. Evidence from the previous studies suggested the efficacy of C. quadrangularis with antimicrobial, anti-diabetic, anti-inflammatory, anti-obesity, anti-oxidant, bone turnover, cardiovascular and hepatoprotective activities. In conclusion, Cissus quadrangularis appears worthy of pharmacological investigations for new drug formulations.

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A Virtual Apparatus for Design and Testing of New Drug Formulations and Devices for Inhalation Therapy

ASME 2007 2nd Frontiers in Biomedical Devices ◽

10.1115/biomed2007-38027 ◽

2007 ◽

Author(s):

Pedro J. Mendes ◽

Joa˜o M. M. Sousa ◽

Joa˜o F. Pinto

Keyword(s):

Respiratory Tract ◽

Systemic Administration ◽

Inhalation Therapy ◽

Drug Formulations ◽

Respirable Fraction ◽

New Drug ◽

Design And Testing

Delivery of drugs to the lungs as aerosols is regarded as an excellent route for local or systemic administration of drugs. Aerosols have been used traditionally for treating illnesses of the respiratory tract (e.g. asthma), but new perspectives and needs on inhalation therapy have recently emerged (e.g. insulin). The percentage of drug that reaches the targeted region, the so-called respirable fraction (RF), is in average only 30% of the dose provided to the patient. Thus, the development of more efficient formulations and devices remains an important issue.

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