Endometrial Endometrioid Adenocarcinoma with Clear Cell Change

Keratin granulomas in the peritoneum are a rare finding with multiple etiologies and can be especially challenging for both the pathologist and the surgeon when these lesions are grossly visible. We report a case of a unique frozen section diagnostic scenario of evaluation of keratin granulomas in the peritoneum of a 47-year-old woman in the setting of multiple potential culprits: endometrial endometrioid adenocarcinoma following fertility sparing treatment, and a concurrent dermoid cyst. We discuss the various etiologies of keratin granulomas in the peritoneum, mechanism of their formation, diagnostic significance, as well as implications of fertility sparing treatments. To the best of our knowledge, this is the only case of keratin granulomas in the peritoneum with multiple distinct potential pathologic culprits as well the only case following fertility sparing treatment.

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Clear Cell Change in Eccrine Glands Is Not Associated With Diabetes

American Journal of Dermatopathology ◽

10.1097/dad.0b013e3181b3ad76 ◽

2010 ◽

Vol 32 (1) ◽

pp. 56-60 ◽

Cited By ~ 4

Author(s):

Paul Cherian ◽

Trevor W Beer

Keyword(s):

Clear Cell ◽

Eccrine Glands ◽

Clear Cell Change

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Expression Pattern of the ASPP Family Members in Endometrial Endometrioid Adenocarcinoma

Onkologie ◽

10.1159/000319692 ◽

2010 ◽

Vol 33 (10) ◽

pp. 500-503 ◽

Cited By ~ 22

Author(s):

Wen-Kang Liu ◽

Xiang-Yang Jiang ◽

Jian-Kang Ren ◽

Zhen-Xi Zhang

Keyword(s):

Expression Pattern ◽

Family Members ◽

Endometrioid Adenocarcinoma ◽

Endometrial Endometrioid Adenocarcinoma

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A Rare Case of Combined Endometrioid Adenocarcinoma Arising from Uterine Adenomyosis and Clear Cell Carcinoma Arising from Parametrial Deep Endometriosis

10.21203/rs.3.rs-495772/v1 ◽

2021 ◽

Author(s):

Yu Huang ◽

Fangyuan Luo

Keyword(s):

Tumor Cell ◽

Cell Carcinoma ◽

Clear Cell ◽

Clear Cell Carcinoma ◽

Endometrioid Adenocarcinoma ◽

Endometrial Stromal Cells ◽

Deep Endometriosis ◽

Cyst Excision ◽

Uterine Adenomyosis ◽

Chocolate Cyst

Abstract Background: Simultaneously malignant transformation from both uterine adenomyoma and deep endometriotic lesions is very rare. Case presentation: We present a case of a 44-year-old nulliparous woman begun with abdominal pain and intestinal obstruction. Past medical history showed laparoscopic ovarian endometriotic cyst excision. Ultrasound indicated adenomyoma and a parametrial hypoechoic nodule with abundant blood flow signals and unclear boundaries. Deep invasive endometriosis was considered preoperatively. The patient underwent laparoscopic subextensive hysterectomy and bilateral adnexa resection. Chocolate cyst-like lesion was observed in the parametiral lesion. Postoperative pathological examinations suggested endometrioid adenocarcinoma arising from eutopic endometrium and adenomyoma. Left parametrial lesions suggested poorly differentiated endometrioid adenocarcinoma combined with clear cell carcinoma. CD10+ endometrial stromal cells was observed surrounding tumor cell masses. The patient underwent subsequent transabdominal tumor cell reduction surgery and chemotherapy.Conclusion: Combined with surgical founding and pathological characters of the left parametrial adenocarcinoma, it was more likely to be carcinomatous changes of the original deep endometriosis.

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