Left Cerebral Hemisphere

2020 ◽  
Author(s):  
1984 ◽  
Vol 246 (6) ◽  
pp. R884-R887
Author(s):  
N. Helm-Estabrooks

It is understood that damage to the left cerebral hemisphere in adulthood may result in syndromes of language disturbances called the aphasias. The study of these syndromes sheds light on normal language processes, the relationship between language behavior and the brain, and how best to treat aphasic individuals. Aphasia, for some, is a central communication disorder affecting all symbolic behavior in all modalities (i.e., speech, writing, and gesture). Difficulty producing symbolic gestures on command is called apraxia. Others view aphasia as a manifestation of a motor-sequencing disorder affecting all gestural systems including those required for speech movements. These divergent theories of the underlying nature of aphasia can be tested through examination of deaf individuals who use sign language before onset of aphasia. Poizner et al. [Am. J. Physiol. 246 (Regulatory Integrative Comp. Physiol. 15): R868-R883, 1984] studied three such patients with different aphasia syndromes: one patient had a nonsymbolic, motor-sequencing disorder; one had a gestural apraxia; and one had neither. These findings force the conclusion that neither the symbolic nor motor-sequencing theory of aphasia can account for the many varieties of that disorder.


2017 ◽  
Vol 75 (11) ◽  
pp. 767-772 ◽  
Author(s):  
Karin Zazo Ortiz ◽  
Joana Mantovani-Nagaoka

ABSTRACT Limb apraxia is usually associated with left cerebral hemisphere damage, with numerous case studies involving aphasic patients. The aim of this study was to verify the occurrence of limb apraxia in aphasic patients and analyze its nature. This study involved 44 healthy volunteers and 28 aphasic patients matched for age and education. AH participants were assessed using a limb apraxia battery comprising subtests evaluating lexical-semantic aspects related to the comprehension/production of gestures as well as motor movements. Aphasics had worse performances on many tasks related to conceptual components of gestures. The difficulty found on the imitation of dynamic gesture tasks also indicated that there were specific motor difficulties in gesture planning. These results reinforce the importance of conducting limb apraxia assessment in aphasic patients and also highlight pantomime difficulties as a good predictor for semantic disturbances.


1986 ◽  
Vol 63 (3) ◽  
pp. 1227-1231 ◽  
Author(s):  
Harriet Williams ◽  
Peter Werner ◽  
George Purgavie

The purpose of the present study was to investigate the nature of the relationship between gross-motor, eye-hand coordination and hemispheric specialization in normal right-handed children. Participants were 30 children, 75–99 mo. 15 boys and 15 girls performed a gross-motor eye-hand coordination task (a controlled, continuous one-handed ball bounce) and a test of hemispheric specialization. A backscreen tachistoscopic projection system was used to present letters and abstract shapes to left and right visual hemifields. A multivariate analysis of variance yielded a significant main effect for eye-hand coordination but not for sex. Follow-up analyses indicated that speed and accuracy of responses to verbal and spatial stimuli presented to the left cerebral hemisphere were significantly related to proficiency of eye-hand coordination. Data suggest that certain aspects of hemispheric specialization may be important to gross-motor eye-hand coordination in young children. Since the left cerebral hemisphere is the major control center for movements of the right side, the hemisphere which controls movements of a particular side may also assume the major responsibility for processing information needed to regulate those movements.


2019 ◽  
Vol 1 (Supplement_2) ◽  
pp. ii37-ii37
Author(s):  
Yasuyoshi Chiba ◽  
Osamu Takemoto ◽  
Junji Yamada ◽  
Takaki Matsumura

Abstract INTRODUCTION Although gliomatosis cerebri is no longer a pathological diagnostic name, it is still an important disease state as a gliomatosis cerebri growth pattern. Here we report a case of gliomatosis cerebri originating from the left cerebral hemisphere that developed whole spinal cord. CASE A 10-year-old boy. He has a history of 13q-syndrome and left retinoblastoma. Left eye enucleation and chemotherapy (modified 98A1) have been performed. MRI in July 2017 showed no abnormalities, but in September 2018, he developed epilepsy. MRI revealed a gliomatosis cerebri that spreads extensively in the left cerebral hemisphere. Biopsy revealed anaplastic astrocytoma (MIB-1 LI; 22%, IDH1 / 2; WT, TERT C228T mutation positive) and IMRT (59.4Gy) and temozolomide (Stupp regimen) were performed in December 2018. In June 2019, neck pain developed. Head and neck MRI revealed that the tumor in the head increased lightly, and there was no suspicion of tumor growth in the brainstem, but the tumor progressed to the entire spinal cord. Therefore, radiation therapy was started from the lower brainstem that had not been irradiated last time to the entire spinal cord, and administration of bevacizumab was started. DISCUSSION Based on the single cell origin theory, the left hemisphere tumor and spinal cord tumor should be continuous. Since gliomatosis cerebri is visualized on MRI only after the tumor volume has increased and edema has occurred, it may appear as if there is no tumor in between. The spinal cord MRI was not taken, so it is only speculation, but it seems that tumor cells had probably infiltrated the spinal cord from the beginning, and it seems that it gradually increased because it was not irradiated. Considering the possibility of remote invasion as in this case, it is necessary to consider taking MRI of spinal cord at the first occurrence.


Neurosurgery ◽  
1988 ◽  
Vol 22 (5) ◽  
pp. 928-933 ◽  
Author(s):  
David G. Munoz ◽  
Robert Griebel ◽  
Bohdan Rozdilsky ◽  
David George

Abstract Two siblings in a family without a history of phacomatosis or cerebral tumors developed malignant tumors in the posterior fossa at age 28 months and in the left cerebral hemisphere at age 15 months, respectively. Dual ependymal and choroid plexus epithelium differentiation was established by histological, ultrastructural, and immunocytochemical studies. The development of this rare tumor in siblings suggests an inherited predisposition, a common environmental insult, or both.


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