Review of: "Fe(II)-phthalocyanine supported on chitosan aerogel as a catalyst for oxidation of alcohols and alkyl arenes"

Kinetics have been studied of oxidation of (1-hydroxybenzyl)ferrocenes substituted in phenyl ring with bis(triphenylsilyl) chromate in benzene solutions as well as protonation of these alcohols in sulphuric acid medium. Logarithms of the oxidation rate constants (kobs, 20-40 °C) and those of the protonation equilibrium constants (KR+, 25 °C) show linear dependence on the Hammett σ constants, the ρ constant values being -0.86 to -0.40 and -2.50, respectively. These negative values suggest that the both processes are influenced by the same effects and confirm the mechanism proposed earlier for oxidation of alcohols with ferrocenyl substituent by action of bis(triphenylsilyl) chromate in aprotic solvents.

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Oxidative transformation of alcohols and organic halides in aqueous solution

New Journal of Chemistry ◽

10.1039/c4nj00393d ◽

2014 ◽

Vol 38 (8) ◽

pp. 3749-3754 ◽

Cited By ~ 9

Author(s):

Neeraj Gupta ◽

Apoorva Thakur ◽

Pushpa Bhardwaj

Keyword(s):

Aqueous Solution ◽

Oxidative Transformation ◽

Organic Halides ◽

Oxidation Of Alcohols

Using water as the only solvent for the oxidation of alcohols and organic halides, a complete solventless process for the preparation of water immiscible aldehydes has been developed.

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β-Ketophosphonates with Pentalenofuran Scaffolds Linked to the Ketone Group for the Synthesis of Prostaglandin Analogs

International Journal of Molecular Sciences ◽

10.3390/ijms22136787 ◽

2021 ◽

Vol 22 (13) ◽

pp. 6787

Author(s):

Constantin I. Tănase ◽

Constantin Drăghici ◽

Miron Teodor Căproiu ◽

Anamaria Hanganu ◽

Gheorghe Borodi ◽

...

Keyword(s):

Lithium Salt ◽

Methyl Esters ◽

Secondary Compounds ◽

Molecular Structures ◽

Keto Group ◽

High Yield ◽

Oxidation Reactions ◽

Prostaglandin Analogues ◽

X Ray ◽

Oxidation Of Alcohols

β-Ketophosphonates with pentalenofurane fragments linked to the keto group were synthesized. The bulky pentalenofurane skeleton is expected to introduce more hindrance in the prostaglandin analogues of type III, greater than that obtained with the bicyclo[3.3.0]oct(a)ene fragments of prostaglandin analogues I and II, to slow down (retard) the inactivation of the prostaglandin analogues by oxidation of 15α-OH to the 15-keto group via the 15-PGDH pathway. Their synthesis was performed by a sequence of three high yield reactions, starting from the pentalenofurane alcohols 2, oxidation of alcohols to acids 3, esterification of acids 3 to methyl esters 4 and reaction of the esters 4 with lithium salt of dimethyl methanephosphonate at low temperature. The secondary compounds 6b and 6c were formed in small amounts in the oxidation reactions of 2b and 2c, and the NMR spectroscopy showed that their structure is that of an ester of the acid with the starting alcohol. Their molecular structures were confirmed by single crystal X-ray determination method for 6c and XRPD powder method for 6b.

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