scholarly journals Polybrominated Biphenyl

2020 ◽  
Author(s):  
1981 ◽  
Vol 57 (1) ◽  
pp. 99-118 ◽  
Author(s):  
B.N. Gupta ◽  
E.E. McConnell ◽  
M.W. Harris ◽  
J.A. Moore

1975 ◽  
Vol 58 (5) ◽  
pp. 978-982
Author(s):  
Norbert V Fehringer

Abstract A method for the determination of polybrominated biphenyls (PBBs) in dairy products is described. Fat is extracted from the products by the official AOAC method. The PBB residues are separated from the fatty material by gel permeation chromatography prior to gas-liquid chromatographic (GLC) quantitation. An additional cleanup using petroleum ether elution through a miniature Florisil column is necessary for thin layer chromatographic (TLC) confirmation. Recoveries of PBBs from samples fortified at levels from 0.1 to 0.5 ppm ranged from 94 to 104% with an average of 99%. GLC sensitivity permits the estimation of PBB residue levels as low as 0.007 ppm. Routine TLC confirmation is limited by sensitivity to ≥0.2 ppm.


2019 ◽  
Vol 28 (10) ◽  
pp. 1755-1764 ◽  
Author(s):  
Nicole C. Deziel ◽  
Javier Alfonso-Garrido ◽  
Joshua L. Warren ◽  
Huang Huang ◽  
Andreas Sjodin ◽  
...  

Epigenomics ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 757-770
Author(s):  
Sarah W Curtis ◽  
Sabrina A Gerkowicz ◽  
Dawayland O Cobb ◽  
Varun Kilaru ◽  
Metrecia L Terrell ◽  
...  

Aim: Michigan residents were exposed to polybrominated biphenyls (PBBs) when it was accidentally added to the food supply. Highly exposed individuals report sex-specific health problems, but the underlying biological mechanism behind these different health risks is not known. Materials and methods: DNA methylation in blood from 381 women and 277 men with PBB exposure was analyzed with the MethylationEPIC BeadChip. Results: 675 CpGs were associated with PBBs levels in males, while only 17 CpGs were associated in females (false discovery rate <0.05). No CpGs were associated in both sexes. These CpGs were enriched in different functional regions and transcription factor binding sites in each sex. Conclusion: Exposure to PBBs may have sex-specific effects on the epigenome that may underlie sex-specific adverse health outcomes.


1975 ◽  
Vol 58 (6) ◽  
pp. 1206-1210
Author(s):  
Norbert V Fehringer

Abstract A new procedure is described for the determination of polybrominated biphenyls (PBBs) in dry animal feeds and developmental results are discussed. Finely ground feed is packed into a chromatographic column containing Celite and then eluted with methylene chloride. The concentrated extract is cleaned up by elution with petroleum ether through Florisil before gas-liquid chromatographic quantitation. Chromatograms thus obtained were essentially free of the interfering peaks encountered when using AOAC methods for pesticide residues in dry products. Results of feed analyses by the proposed procedure averaged 30% higher than those obtained by AOAC procedures. Recoveries of PBBs from samples fortified at levels of 0.04 to 0.4 ppm ranged from 90 to 104%, with an average of 98%.


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