scholarly journals Three-month Effects of Immunotherapy on Clinical Features and Pulmonary Function Tests of Patients with Allergic Rhinitis Concomitant with or without Asthma

Acta Medica ◽  
2020 ◽  
Vol 51 (4) ◽  
pp. 41-47
Author(s):  
Guzin Ozden ◽  
Pelin Duru Cetinkaya

Objective: We aimed to evaluate our patient’s treatment responses to three-month immunotherapy for allergic rhinitis with or without asthma, and to investigate the factors affecting treatment Material and Methods: A total of 53 patients receiving subcutaneous immunotherapy for allergic rhinitis with or without asthma were included in the study. All patients were positive for mite skin prick test. Asthma was present as a concomitant disease in 28(52.8%) patients. Patients with and without asthma were classified in two groups as “Allergic rhinitis + Asthma+” and “Allergic rhinitis+ Asthma-“. The values of pulmonary function tests of all patients, and in rhinitis with asthma patients, the Asthma Control Test scores before and after three months of treatment were recorded. Results: In “Allergic rhinitis + Asthma+” and “Allergic rhinitis + Asthma-“groups, male/female ratio was 7/21 and 10/15, mean age was 33±9 and 32±9 years. No statistically significant differences were present between the pre-treatment and 3-month-treatment values of pulmonary function test. The difference between the pre-treatment and 3-month treatment asthma control test scores was strongly significant. Conclusion: In allergic rhinitis, which is quite commonly associated with asthma, the control of asthma is also provided with the treatment of allergic rhinitis. By using pulmonary function test in allergic rhinitis and asthma control test in asthma, we showed that the effectiveness of allergen specific immunotherapy started in 3 months which was earlier from current literature.

Author(s):  
Sadaf Choudhary ◽  
Keya Rani Lahiri ◽  
Fehmida Najmuddin

Introduction: Allergic Rhinitis and Asthma adversely affects height in children and it could be considered as an objective tool to assess severity, compliance and lung functions in children. We studied the correlation between height and pulmonary function tests with classification of allergic rhinitis and asthma. Aims & Objectives: 1) To study the height parameter with the grade of asthma and allergic rhinitis 2) To evaluate the pulmonary function test with the severity of asthma and allergic rhinitis 3) To correlate height and pulmonary function test with the classification of asthma and allergic rhinitis. Material and Methods: A prospective study including 30 patients in the age group of 5-12 years diagnosed with allergic rhinitis (AR) and bronchial asthma was conducted in a private tertiary care hospital in Navi Mumbai. History was entered in a pre-designed proforma and height was measured using a calibrated stadiometer along with pulmonary function tests recorded at the initial and two visits, 3 months apart. Results: Height increased significantly in patients without AR (p-value<0.01), with mild intermittent (p-value=0.02) and mild persistent AR (p-value<0.01) on subsequent visits. Patients with intermittent, mild persistent and moderate persistent asthma showed a statistically significant increase in height (p-value<0.01) with subsequent assessments. No significant increase in height was noted in patients with moderate persistent AR (p-value=0.14) and severe persistent asthma (p-value=0.16). At baseline, the height correlated significantly with FEV1 (p value<0.01), FVC (p value<0.01), Pre and Post-PEFR (p value<0.01, each). This trend continued at the first follow up. At the second follow-up, height correlated significantly with all parameters of pulmonary function tests (p value<0.01 for FEV1, FVC, FEV1/FVC ratio and PEFR). Conclusion: Height correlation with classification of AR and Asthma along with pulmonary function test has emerged as a simple, safe, cost-effective method in assessing control and monitoring the disease.


2019 ◽  
Vol 6 ◽  
Author(s):  
Margherita Neri

The present issue of Multidisciplinary Respiratory Medicine includes a paper by Bora et al. [1] investigating the relationship between the asthma control test (ACT) and airway inflammation. In a group of stable asthmatic patients admitted to a pulmonary outpatient clinic, the authors carried out the ACT, pulmonary function tests, methacholine bronchial provocation test (MBPT), fractional exhaled nitric oxide level (FeNO), and induced sputum test. [...]


2007 ◽  
Vol 23 (3) ◽  
pp. 125-132 ◽  
Author(s):  
Iraj Mohebbi ◽  
Isa Abdi Rad

Background: A secondary spontaneous pneumothorax is a complication of an underlying pulmonary disease. In recent years, there have been only a few scattered reports of patients with silicosis also having a pneumothorax. Silicosis, a form of disabling pulmonary fibrosis, is a well-known occupational disease resulting from high-level exposure to silica or silica-containing dusts. The objective of the present study was to elucidate any associations between the occurrence of a pneumothorax, and pulmonary function tests and clinical observations performed prior to the pneumothorax; these two factors may be predictors for a pneumothorax among workers exposed primarily to silica-containing respirable dust. Methods: A diagnosis of silicosis was made on several factors: silica dust exposure, appropriate interval of time after exposure, clinical findings, pulmonary function tests and chest radiological findings. A checklist was designed for collecting data of occupational history, respiratory signs, and symptoms from onset of dust exposure to the occurrence of a pneumothorax. Spirometery was conducted in accordance to the recommendations of standard protocols and guidelines posited by the American Thoracic Society. Autopsies were performed in three cases where the patient had suffered a pneumothorax due to silicosis. Mann—Whitney U-tests and Fisher's exact tests were used to determine any associations between pneumothorax and predictor factors. Results: An association between a progressive decrease in pulmonary function test values and a pneumothorax was observed. The occurrence of a pneumothorax was associated with complaints of pleuretic chest pain, resting dyspnea, respiratory distress, paroxysmal nocturnal dyspnea, orthopnea and crackle. Conclusion: A characteristic decline in pulmonary function test values and the severity of respiratory impairment may facilitate the occurrence of a pneumothorax in silicosis. Toxicology and Industrial Health 2007; 23: 125—132.


2021 ◽  
Vol 6 (3) ◽  
pp. 236-243
Author(s):  
Krupa Pareshbhai Patel ◽  
Anjali Bhise

Background: Spirometry is a universal, simple, and non-invasive pulmonary function test. Spirometry, along with calculation of the forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), is helpful for diagnosing obstructive or restrictive lung disease. Postoperative Pulmonary Complications are defined as unintended pulmonary abnormalities that occur as a result of surgery which cause identifiable dysfunction. Purpose: To find the evidence showing the importance of pre-operative PFT to predict risk of pulmonary complications after abdominal surgery Methodology: The study was conducted according to Preferred Reporting Items for systematic reviews and meta-analysis guidelines. Evidences selected since year 2002- 2020 from PubMed, Google Scholar, Physiotherapy Evidence Database (PEDro), ResearchGate and ScienceDirect. Key words used were: Pulmonary Function Tests, Post-Operative Pulmonary Complications, and Abdominal Surgery. Analysis was done using 2 scales: Centre for Evidence-Based Medicine Levels of Evidence Scale. Total 12 articles were found. Among them 10 were selected. Results: 5 articles showed that preoperative PFT is important in prediction of PPCs while the other half concluded that routine preoperative spirometry is not necessary before non-thoracic surgeries. Conclusion: Based on evidences, in the nutshell it is reviewed that there is controversy regarding the value of preoperative pulmonary functions test in non-thoracic surgeries. Keywords: Pulmonary Function Tests, Post-Operative Pulmonary Complications, and Abdominal Surgery


2021 ◽  
pp. 30-31
Author(s):  
Bibhore Sengupta ◽  
Suman Sarkar ◽  
Nirmalya Roy ◽  
Ankan Pathak ◽  
Nikhil Sonthalia ◽  
...  

Pulmonary Function Tests are one of the prime tool to evaluate respiratory symptoms and diagnose disease. It is also used for functionality and preoperative risk evaluation.Many organizations, including the National Asthma Education and Prevention Program, Global Initiative for Chronic Obstructive Lung Disease (GOLD), and American Thoracic Society (ATS), recommend using these tests.(1–3)When added to correlate with clinical history. Pulmonary Function Test have an high accuracy in predicting the diagnosis and further management of the patient. Pulmonary function test assesses the integrated mechanical function of the lung, chest wall, respiratory muscles, and airways and is valuable tool in evaluating patients with respiratory symptoms


2009 ◽  
Vol 46 (7) ◽  
pp. 677-682 ◽  
Author(s):  
Ryuji Sato ◽  
Katsuyuki Tomita ◽  
Hiroyuki Sano ◽  
Hideo Ichihashi ◽  
Shigeyoshi Yamagata ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document