scholarly journals STUDY OF THE RISK FACTORS FOR CORONARY ARTERY DISEASE AND THEIR CORRELATION WITH THYROID HORMONE PROFILE AMONGST WOMEN WITH ST SEGMENT ELEVATION IN ACUTE MYOCARDIAL INFARCTION

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Dr. Jitendra Kodilkar ◽  
Dr Jeetendra Singh ◽  
Dr. Akash Berad ◽  
Dr. Mayur Babras ◽  
Dr. Imran Pinjari ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Thyroid Hormone ◽  
St Segment Elevation ◽  
Hormone Profile ◽  
St Segment ◽  
Study Population ◽  
Artery Disease

Background: To assess risk factors for coronary artery disease and their correlation with thyroid hormone profile amongst women with ST segment elevation in acute myocardial infarction. Method: A total number of 78 females having ST elevation myocardial infarction diagnosed through detailed clinical history and ECG evaluations were included after they satisfy the eligibility criteria. Patients were subsequently evaluated for presence of risk factors of ischemic heart disease such age, marital status, parity, and menopause, use of oral contraceptives, family history, obesity, diabetes mellitus, hypertension, hypercholesterolemia and hypertriglyceridemia. Their thyroid hormone profiles (T3, T4, TSH) were done and were correlated with risk factors for ischemic heart disease. Result: A total 78 patient included in the study. Most of the study population belongs to the age group of 40 to 50 years (43.6 %). Hypertension was the most common clinical features amongst study population (59%) followed by Diabetes (50%). most of the study population had Normal Thyroid status (57.69%) followed by Hypothyroidism (25.64%) and Hyperthyroidism (16.67%). and SERUM TSH is the most sensitive test for evaluation. Diabetes Mellitus was statistically significant risk factor (p value <0.05) in patients with STEMI with different levels of thyroid. Conclusion: Patients with coronary artery disease especially in the presence of other risk factors should be screened for diabetes and also for thyroid dysfunction as in our study cases of Hypothyroidism was seen in 25.64% of the population under study. Hence it can be postulated that hypothyroidism may be a predictor for myocardial injury in STEMI. Here we recommend that tests for thyroid disorders in acute coronary syndrome can give predictor for risk of morbidity and mortality in those subjects. These results also may warrant further larger study to investigate whether reversing the hypothyroidism could benefit the STEMI patients. Keywords: STEMI- ST segment elevation myocardial infarction, MI- Myocardial Infarction, Hyperthyroidism, Hypothyroidism, TSH- Thyroid Stimulating Hormone

scholarly journals Pre-infarction angina – a problem more common than one might think. Role of general practitioners according to the 2019 ESC Clinical Practice Guidelines

2020 ◽  
Vol 16 (4) ◽  
pp. 389-395
Author(s):  
Małgorzata Wojciechowska ◽  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Artery Disease ◽  
Test Probability

Background and aims: Some patients present with stenocardial pain long before the onset of myocardial infarction. The aim of the study was to evaluate the mean frequency and duration of typical angina pectoris preceding ST-segment elevation myocardial infarction. In addition, the article addresses the role of general practitioners in the diagnosis of patients with suspected coronary artery disease. Material and methods: The study included a total of 120 patients without prior diagnosis of coronary artery disease who were admitted to the invasive cardiology department with ST-segment elevation myocardial infarction. All patients were assessed to determine symptoms preceding myocardial infarction and risk factors for coronary artery disease. In addition, their pre-test probability of disease was estimated. Results: Out of 120 patients, 43 (35.8%) presented with typical angina symptoms preceding myocardial infarction. The median duration of symptoms was 45 days (min 4, max 2,190 days!), and symptoms recurring for ≥2 weeks were found in 35 patients. The estimated pre-test probability of coronary artery disease was >15% in 40 (93%) patients, and the risk factors for coronary artery disease were prevalent. Conclusions: Typical exertional angina preceding myocardial infarction occurred in over 35% of patients. In some of them, it persisted for a number of months. The estimated probability of coronary artery disease in nearly all patients was >15%. Based on the collected data, the authors conclude that there is a need for broadly understood education so as to improve the understanding of typical anginal symptoms. Correct recognition of symptoms by physicians and patients can significantly reduce the incidence of myocardial infarction and, consequently, bring down the prevalence of heart failure, and decrease mortality rates in patients with coronary artery disease.

scholarly journals Comparison of Risk Factors & Angiographic Profiles between Young Patients with ST Segment Elevation Myocardial Infarction and Non-ST Segment Elevation Myocardial Infarction

2021 ◽  
Vol 36 (2) ◽  
pp. 124-132
Author(s):  
Sayeedur Rahman Khan ◽  
Fazila Tun Nesa Malik ◽  
Mir Nesaruddin Ahmed ◽  
Asim Kumar Biswas ◽  
Mainul Islam ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Young Patients ◽  
St Segment Elevation ◽  
Vessel Disease ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Artery Disease

Background: Coronary artery disease is the leading cause of death in the world. Advancing age is a well-recognized risk factor for acute myocardial infarction (AMI). Myocardial infarction is less common in young adults. Prevalence of acute coronary syndrome in young individuals is increasing progressively. These patients have different risk profile, presentation and prognosis. Early recognition and risk factor modification in this population sub-set is of key importance. Objectives: The purpose of the present study was to determine the differences in risk factors and coronary angiographic profile of young patients with ST-segment elevated myocardial infarction (STEMI) vs. those with non-ST-segment elevated myocardial infarction (NSTEMI). Methods: In this cross sectional analytical study total 135 patients (70 STEMI and 65 NSTEMI) aged ≤45 years were enrolled to see the differences of risk factors and angiographic profile. Results: The mean age of the study population was 39.39±5.12 years and the study showed male predominance (90.40 % was male and 9.60 % was female). Smoking/tobacco consumption was significantly higher in STEMI patients, whereas diabetes mellitus and hypertension were more prevalent in NSTEMI patients. The frequency of single vessel disease and involvement of left anterior descending artery was significantly higher in young STEMI patients. In case of young NSTEMI patients frequency of triple vessel disease, noncritical coronary artery disease and involvement of left circumflex coronary was significantly higher. The frequency of double vessel disease and involvement of left main coronary artery was also nonsignificantly higher in young NSTEMI patients. There was no significant difference regarding involvement of right coronary artery. Conclusion: There are significant differences between young STEMI and young NSTEMI patients in respect to risk factors and angiographic profile. Key words: Young patient, STEMI, NSTEMI, Risk factors, Coronary angiographic profile. Bangladesh Heart Journal 2021; 36(2): 124-132

scholarly journals Correlation between the Clinical Profile and Angiographic Severity of Coronary Artery Disease in ST Elevation Myocardial Infarction and Non-ST Elevation Myocardial Infarction Patients

2021 ◽  
Author(s):  
C. Rohit Swaminathan ◽  
P. Arun Prasath
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Clinical Profile ◽  
Syntax Score ◽  
St Segment Elevation ◽  
St Segment ◽  
Study Population ◽  
St Elevation ◽  
Artery Disease

Background and Aim: The correlation between clinical profile and angiographic severity in acute coronary syndrome (ACS) patients has been poorly documented. Hence, the present study aimed to study the clinical profile and correlate that with vessel burden, as witnessed by coronary angiography, in patients presenting to the hospital with ACS (ST-segment elevation myocardial infarction [STEMI]/non-ST-segment elevation [NSTE]-ACS) Materials and Methods: The study had enrolled 209 patients who had been diagnosed with ACS. All subjects were those who presented to the Emergency Medicine Department in a tertiary care center (south India). Coronary angiogram done for these patients by cardiologists was reviewed with a SYNTAX CALCULATOR (I AND II). Patient's baseline characteristics and clinical examination and interventional diagnosis details were obtained. Results: The clinical profile gathered from this geographical territory implied an increase in the angiographic severity of the coronary artery disease as measured by the SYNTAX score 1, with an increase in the duration of the said risk factor. Male gender was predominant and the major age group for ACS was 30 to 60 years. The most common presentation in ACS was STEMI. Diabetes and hypertension were the main risk factors for ACS. There was a striking occurrence of ACS among the young. Conclusion: STEMI was the major ACS presentation in this study population. The main risk factors noted were diabetes and hypertension. Besides smoking and alcohol abuse (in any study population), dyslipidemia was also a key risk factor observed. Mild left ventricular systolic dysfunction was predominant in this study. The SYNTAX score 1 increased with duration of observed and recorded risk factors.

scholarly journals Ventricular Rupture due to Myocardial Infarction without Obstructive Coronary Artery Disease

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Hendrik Lapp ◽  
Marcel Keßler ◽  
Thomas Rock ◽  
Franz X. Schmid ◽  
Dong-In Shin ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Obstructive Coronary Artery Disease ◽  
Left Ventricular ◽  
St Segment Elevation ◽  
St Segment ◽  
Ventricular Rupture ◽  
Life Threatening ◽  
Artery Disease

An 87-year-old woman presenting with myocardial infarction and ST-segment elevation in the electrocardiogram suffered from pericardial effusion due to left ventricular rupture. After ruling out obstructive coronary artery disease and aortic dissection, she underwent cardiac surgery showing typical infarct-macerated myocardial tissue in situ. This case shows that even etiologically unclear and small-sized myocardial infarctions can cause life-threatening mechanical complications.

Sign in / Sign up

Export Citation Format

Share Document