scholarly journals IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA

2019 ◽  
Vol 3 (1) ◽  
pp. 47-54
Author(s):  
Meidyta Sinantryana Widyaswari ◽  
Hans Lumintang ◽  
Troef Soemarno

Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.

2020 ◽  
Vol 3 (S2) ◽  
pp. 7-8
Author(s):  
Sara Dahhouki ◽  
◽  
Kaoutar Achehboune ◽  
Mounia Bennani ◽  
Zakia Douhi ◽  
...  

The Buschke-Löwenstein tumor, also known as, giant condyloma acuminatum is an extremely rare sexually transmitted disease associated due to human papilloma virus infection, mostly Type 6 or 11.


e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Stella R. Nelwan ◽  
Nurdjannah J. Niode ◽  
Marlyn G. Kapantow

Abstract: Condyloma acuminata, also known as genital warts, is a vegetation of certain types of Human Papilloma Virus(HPV), stalky with bumpy surface. This disease is a sexually transmitted disease, most HPV infections in anogenital area are acquired during sex. This was a descriptive retrospective study, where the data were collected from medical records and registers book of sexually transmitted disease (STD) in Dermatovenereology clinic of Prof. Dr. R. D. Kandou Hospital Manado. The result showed that in 2012, there were 27 new cases of condyloma acuminata, 2.46% of all new patients Most age group found was 25-44 years which was 13 patients (48.15%), with sex distribution mostly found in female patients which was 14 patients (51.85%). Most occupation found was private employees by 10 patients (37.04%). Most affected locations in female patients was vulva and vulva with vagina by 5 patients each of them (35.71%), where as in male patients was penis which was found in 4 patients. The result also showed that HIV was the most comorbid disease found in 3 patients (11.11%). Conclusion: In this study, most condyloma acuminata patients is in 25-44 age group, mostly found in female, most occupation was private employee, most location affected in female were vulva and vulva with vagina, while in male patients was penis, most therapy used was podophyllin. Most comorbid disease was HIV. Keywords: Condyloma acuminata, Human papilloma virus, female    Abstrak: Kondiloma akuminata (KA) adalah vegetasi oleh Human Papilloma Virus (HPV) tipe tertentu, bertangkai dengan permukaannya berjonjot. Penyakit ini tergolong infeksi menular seksual, kebanyakan infeksi HPV di daerah anogenital didapatkan melalui hubungan seksual. Penelitian ini bersifat deskriptif retrospektif; data diambil dari rekam medik dan buku register infeksi menular seksual bagian ilmu penyakit kulit dan kelamin RSU Prof. Dr. R. D. Kandou Manado. Hasil penelitian memperlihatkan pada tahun 2012 dari total kunjungan baru terdapat 27 kasus baru KA (2,46%). Kelompok umur terbanyak didapatkan adalah 25-44 tahun sebanyak 13 orang (48,15%) dengan jenis kelamin terbanyak perempuan sebanyak 14 orang (51,85%) Pada pekerjaan terbanyak pada pekerja swasta sebanyak 10 orang (37,04%) Lokasi lesi pada perempuan tersering di vulva dan vulva ditambah vagina masing-masing sebanyak 5 orang (35,71%), sedangkan pada laki-laki tersering di penis yaitu sebanyak 4 orang. Hasil penelitian juga didapatkan penyakit penyerta terbanyak adalah HIV sebanyak 3 orang (11,11%) . Simpulan: Dalam Penelitian ini, pasien KA terbanyak pada kelompok umur 25-44 tahun paling banyak pada perempuan, jenis pekerjaan pegawai, lokasi lesi pada perempuan tersering pada vulva dan vulva ditambah vagina sedangkan pada laki-laki tersering di penis, pengobatan tersering podofilin. Penyakit penyerta ada lah HIV. Kata kunci: Kondiloma Akuminta, Human papilloma virus, Perempuan.


Author(s):  
A. Sarin ◽  
V. G. Binesh ◽  
Betsy Ambooken ◽  
S. Suprakasan

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Condylomata acuminata (CA) or genital wart is a sexually transmitted infection (STI) caused by human papilloma virus (HPV). As there was little information about the HPV types commonly causing CA in our state, we decided to study the clinico-epidemiological profile of CA with special emphasis on HPV typing.</span></p><p class="abstract"><strong>Methods:</strong> We did <span lang="EN-IN">HPV typing in 25 clinically diagnosed cases of CA. The biopsied specimens were sent for HPV typing using Polymerase chain reaction (PCR) and those with high risk HPV types were histologically analyzed for any dysplastic change. We also evaluated for other STIs which can coexist with CA</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Out of the 25 cases, 18 (72%) were males and 7 (28%) females. Majority of our patients belonged to 21-40 year age group (64%). Clinical types of CA were the classical fleshy exuberant type in 22 patients (88%), flat type in 2 (8%) and keratotic type in 1 (4%). HPV positivity was obtained in 21 (84%). The most common type was HPV 6 in 10 cases (40%) and HPV 11 in 8 (32%) patients. HPV 16 alone was isolated in 1 (4%) case. HPV types 6 and 16 and 11 &amp; 18 were isolated in one case each. Dysplastic changes were observed in two cases with HPV 16 and 18. VDRL and TPHA positivity was found in 2 (8%) males and HBsAg positivity was seen in 1 (4%) male patient. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">This study highlights the importance of HPV typing for identifying the high risk types and to assess the efficacy of HPV vaccines.</span></p>


2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Rikinder Sandhu ◽  
Zaw Min ◽  
Nitin Bhanot

Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It is a neoplasm of the anogenital region which has benign appearance on histopathology but is locally destructive. It carries a high recurrence rate and a significant potential for malignant transformation. Human papilloma virus has been implicated as an etiologic agent for this tumor. Since this disease is rare and no controlled studies exist, radical excision of this anogenital lesion is generally recommended as the first line therapy and close vigilance and followup are essential. We have discussed an overview of etiopathogenesis, clinical presentation, diagnosis, and management of this uncommonly encountered disease.


2016 ◽  
Vol 15 (3) ◽  
pp. 382 ◽  
Author(s):  
Juliana Alexandra Parente Sá Barreto ◽  
Mirna Neyara Alexandre de Sá Barreto Marinho ◽  
Emery Ciana Figueiredo Vidal ◽  
Antônio Germane Alves Pinto ◽  
Priscila De Souza Aquino ◽  
...  

Aim: to understand the feelings of women infected with the human papilloma  virus  (HPV)  regarding  this  sexually  transmitted  disease.  Method:  this  is  an exploratory study, with a qualitative approach, performed with 14 women who are users of  a  specialized  care  service  in  the  municipality  of  Juazeiro  do  Norte,  in  the  Brazilian state  of  Ceará,  in  the  Northeast  of  Brazil,  between  March  and  June  2012,  using  the Collective  Subject  Discourse  technique.  Results:  it  was  observed that there  were some misconceptions  regarding  HPV,  unfamiliarity  with  the  fact the  therapies  used  do  not eliminate the virus, feelings linked to negative characteristics of the diagnosis, and self-protecting and children-protecting attitudes. Conclusion: the perceptions described tend to  harm  the  empowerment  process  of  these  women  to  deal  with  the  illness  with  more confidence.  Gaps  were  found  in  health  education.  The  discussion about  the  topic  must continue,  with  directed  information  regarding  living  with  HPV  in  a  singular  approach, respecting the individuality of each woman, providing more humane and effective care.


2021 ◽  
Vol 4 (3) ◽  
pp. 82
Author(s):  
Putri Cinthya Ismihari ◽  
Riyana Noor Oktaviyanti

Condyloma acuminata is a sexually transmitted disease caused by the Human Papilloma Virus (HPV). During pregnancy, condyloma acuminata can proliferate rapidly due to changes in immunity and increased blood supply. One of the safest therapeutic modalities is trichloroacetic acid (TCA). Electrocautery is another modality in pregnant patients.  A 16-year-old woman, 6-months pregnant, complained of a wart-like lump in the pubic area getting more prominent since the last two weeks and covering the vagina surface. The lump is not itchy and painless. From history-taking it was found that patient often changes partners. On physical examination, the lesions were multiple papules with a verrucous surface. The results of the work-up showed a positive acetowhite test. Patients are then treated with a TCA of 80-90% during pregnancy and followed by electrocautery and excision during cesarean section. The results of 80-90% TCA treatment followed by electrocautery and excision were satisfactory, and there were no recurrences when the patient went for a follow-up. TCA is a substance that is caustic and can erode skin and mucous membranes. TCA works by coagulation of proteins which causes dryness of cells and tissues. TCA is safe for pregnant women. Combination of TCA 80-90% with electrocautery and excision, in this case, proved to be effective with no sign of recurrence. The combination of TCA therapy with electrocautery and excision has proven effective and safe for pregnant patients.


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