scholarly journals SLICC 2012: Kriteria Klasifikasi SLE

2019 ◽  
Vol 2 (2) ◽  
pp. 48-59
Author(s):  
Prema Hapsari Handayani
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Skin Disease ◽  
Discoid Lupus Erythematosus ◽  
Systemic Lupus ◽  
Neonatal Lupus ◽  
Drug Induced ◽  
Neonatal Lupus Erythematosus

Istilah Lupus diambil dari bahasa latin yang berarti serigala dan dipakai pertama kali pada abad pertengahan untuk menggambarkan lesi kulit yang erosive yang mirip dengan gigitan serigala. Pada tahun 1846 seorang ahli  dari Vienna bernama Ferdinand von Hebra memperkenalkan istilah “kupu-kupu” untuk menggambarkan rash di daerah malar dan menyebutnya sebagai lupus erythematosus . Ilustrasi ini dipublikasikan pertama kali dalam bukunya berjudul Atlas os Skin Disease pada tahun 1856.  Lupus kemudian dibagi menjadi tiga bentuk, yaitu Discoid Lupus Erythematosus,Neonatal Lupus Erythematosus, Drug Induced Lupus dan Systemic Lupus Erythematosus.

Сase of neonatal lupus in one of two children of dichorial diamniotic pregnancy in a woman with unrecognized systemic lupus erythematosus and lupus nephritis

2020 ◽  
Vol 24 (2) ◽  
pp. 88-95
Author(s):  
T. V. Kirsanova ◽  
N. F. Kravchenko ◽  
A. I. Balakireva
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Treatment Options ◽  
Interdisciplinary Approach ◽  
Reproductive Function ◽  
Modern Medicine ◽  
Systemic Lupus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus ◽  
Management Approaches

The ability to realize the reproductive function for both patients with systemic lupus erythematosus and patients with a different cause of chronic kidney disease is rightfully considered as one of the most important achievements of modern medicine. The work describes the pregnancy case of the patient with systemic lupus erythematosus and secondary antiphospholipid syndrome. Renal damage with the development of renal thrombotic microangiopathy came to the fore in the clinical picture, which was regarded as nephritis and complicated the diagnosis of systemic lupus erythematosus. A positive pregnancy outcome was achieved with the development of neonatal lupus erythematosus in one twin child. The options for the prevention and treatment of thrombotic complications as well as methods for minimizing gestational complications (including preeclampsia, which the patient had in history) are discussed, inter alia, with the purposed of low-molecular-weight heparins and acetylsalicylic acid preparations. Treatment options are also described to improve the outcome of such pregnancies and to decrease the symptoms of neonatal lupus erythematosus using hydroxychloroquine. The article summarizes current management approaches for these patients with special attention to the interdisciplinary approach.

Systemic Lupus Erythematosus With Libman-Sachs Endocarditis in a 9-Month-Old Infant With Neonatal Lupus Erythematosus and Congenital Heart Block

PEDIATRICS ◽  
1989 ◽  
Vol 84 (3) ◽  
pp. 574-578
Author(s):  
JOANNE MARIE JORDAN ◽  
PAUL VALENSTEIN ◽  
DEBORAH W. KREDICH
Keyword(s):  
Lupus Erythematosus ◽  
Heart Block ◽  
Congenital Heart ◽  
Congenital Heart Block ◽  
Discoid Lupus Erythematosus ◽  
Cardiac Abnormality ◽  
Transplacental Passage ◽  
Systemic Lupus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Since the first report of a patient with a congenital discoid lupus erythematosus rash in 1954 by McCuistion and Schoch, multiple instances of neonatal lupus erythematosus have been described. It is now a well-described syndrome of congenital heart block, transient rash, or both, associated with transplacental passage of antibodies to Sjogren's syndrome A (Ro/SSA) from mothers with overt or latent connective tissue disease. The syndrome usually resolves when the infant is 6 months of age. Neonatal lupus erythematosus without congenital heart block is thus thought to be a transient, relatively benign, phenomenon. Even with congenital heart block, the prognosis can still be good, especially in the absence of structural cardiac abnormality.

TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS COMPLICATED BY NEPHRITIS IN CHILDREN

PEDIATRICS ◽  
1967 ◽  
Vol 40 (5) ◽  
pp. 822-827
Author(s):  
Wolfgang W. Hagge ◽  
Edmund C. Burke ◽  
Gunnar B. Stickler
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Clinical Course ◽  
Discoid Lupus Erythematosus ◽  
High Dose ◽  
Low Doses ◽  
Systemic Lupus ◽  
Drug Induced ◽  
High Doses

The clinical course of 41 patients who had systemic lupus erythematosus complicated by nephritis with symptoms beginning before they were 15 years old was reviewed. The retrospective analysis showed a definite trend toward prolonged survival among the patients receiving high doses of steroids, compared to those receiving no or low doses. We conclude that it is no longer justified to withhold high-dose steroid therapy from children with lupus nephritis, but it should be emphasized equally that this does not apply to children with discoid lupus erythematosus, rheumatoid arthritis with a positive LE clot test, or drug-induced lupus erythematosus. Our present plan of management is outlined.

scholarly journals Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2091002 ◽  
Author(s):  
Umut Selamet ◽  
Ramy M Hanna ◽  
Anthony Sisk ◽  
Lama Abdelnour ◽  
Lena Ghobry ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Interstitial Nephritis ◽  
Lupus Erythematosus ◽  
Kidney Biopsy ◽  
Kidney Injury ◽  
Acute Interstitial Nephritis ◽  
Systemic Lupus ◽  
Drug Induced ◽  
Systemic Manifestations

Drug-induced lupus erythematosus has features distinct from primary systemic lupus erythematosus. It can occur with a wide variety of agents that result in the generation of anti-histone or other types of antibodies. Systemic manifestations of drug-induced systemic lupus erythematosus may include renal dysfunction due to circulating immune complexes or due to other immune reactions to the culprit medication(s). Acute interstitial nephritis occurs due to DNA–drug or protein–drug complexes that trigger an allergic immune response. We report a patient who developed acute kidney injury, rash, and drug-induced systemic lupus diagnosed by serologies after starting chlorthalidone and amiodarone. A renal biopsy showed acute interstitial nephritis and not lupus-induced glomerulonephritis. It is important to note that systemic lupus erythematosus and acute interstitial nephritis can occur together, and this report highlights the role of the kidney biopsy in ascertaining the pathological diagnosis and outlining therapy in drug-induced lupus erythematosus.

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