scholarly journals Pressurized Liquid Extraction of Hemp Residue and Purification of the Extract with Liquid-Liquid Extraction

2021 ◽  
Author(s):  
János Béri ◽  
Sára Nagy ◽  
Ádám Kolay Kovács ◽  
Erika Vági ◽  
Edit Székely
Keyword(s):  
Operation Time ◽  
Liquid Extraction ◽  
Pressurized Liquid Extraction ◽  
Mass Consumption ◽  
Independent Variables ◽  
Liquid Liquid Extraction ◽  
Extraction Study ◽  
Full Factorial Experimental Design ◽  
Full Factorial ◽  
Two Parameter

The first semi-continuous Pressurized Liquid Extraction (PLE) of hemp threshing residue with ethanol was carried out according to a 32 full factorial experimental design with pressure and temperature as independent variables at 8-10-12 MPa and 323-333-343 K, respectively. The total- and cannabidiol (CBD) yield curves were fitted to the modified two-parameter Brunner equation. Best results, concerning CBD, can be achieved at 12 MPa and 343 K. Solvent mass-consumption and operation time were considerably decreased compared to a previous supercritical fluid extraction study on the same material. Furthermore, the concentration profiles were evaluated to study the mass transfer. The winterized dry extracts were further studied in a methanol-hexane-water ternary system concerning CBD distribution ratio, showing high methanol dependency.

scholarly journals Optimization of moist and oven-dried bacterial cellulose production for functional properties

2021 ◽  
Author(s):  
Ioana Maria Bodea ◽  
Florin Ioan Beteg ◽  
Carmen Rodica Pop ◽  
Adriana Paula David ◽  
Mircea Cristian Dudescu ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Physical And Mechanical Properties ◽  
Young Modulus ◽  
Culture Conditions ◽  
Independent Variables ◽  
Optimization Study ◽  
Full Factorial Experimental Design ◽  
Experimental Values ◽  
Inoculum Volume ◽  
Full Factorial

Abstract Bacterial cellulose (BC) is a natural polymer with properties suitable for tissue engineering and possible applications in scaffold production. However, current procedures have limitations in obtaining BC pellicles with the desired structural, physical, and mechanical properties. Thus, this study analyzed the optimal culture conditions of BC membranes and 2 types of processing: draining and oven-drying. The aim was to obtain BC membranes with properties suitable for a wound dressing material. Two studies were carried out. In the preliminary study the medium (100 mL) was inoculated with varying volumes (1; 2; 3; 4; and 5 mL) and incubated statically for different periods (3; 6; 9; 12; and 18 days), using a full factorial experimental design. Thickness, uniformity, weight, and yield were evaluated. In the optimization study, a Box–Behnken design was used. Two independent variables were used: inoculum volume (X1: 1; 3; and 5 mL) and fermentation period (X2: 6; 12; and 18 d) to determine the target response variables: thickness, swelling ratio, drug release, fiber diameter, Tensile strength, and Young's Modulus for both dry and moist BC membranes. The mathematical modelling of the effect of the 2 independent variables was accomplished by response surface methodology (RSM). The obtained models were validated with new experimental values, and confirmed for all tested properties, except Young Modulus of oven-dried BC. Thus, the optimal properties in terms of a scaffold material of the moist BC were obtained with an inoculum volume of 5% (v/v) and 16 d of fermentation. While, for the oven-dried membranes a 4% (v/v) and 14 d of fermentation.

New organic extractant based on pyridazinone scaffold compounds: Liquid-liquid extraction study and DFT calculations

2019 ◽  
Vol 1191 ◽  
pp. 24-31 ◽  
Author(s):  
Fouad El Kalai ◽  
Tarik Chelfi ◽  
Noureddine Benchat ◽  
Brahim Hacht ◽  
Mohamed Bouklah ◽  
...  
Keyword(s):  
Dft Calculations ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Extraction Study ◽  
Organic Extractant

scholarly journals Rapid Determination of Sotolon in Fortified Wines Using a Miniaturized Liquid-Liquid Extraction Followed by LC-MS/MS Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Vanda Pereira ◽  
João M. Leça ◽  
João M. Gaspar ◽  
Ana C. Pereira ◽  
José C. Marques
Keyword(s):  
Rapid Determination ◽  
High Sensitivity ◽  
Liquid Extraction ◽  
Single Step ◽  
Alcoholic Beverages ◽  
Liquid Liquid Extraction ◽  
Sweet Wines ◽  
Fortified Wines ◽  
Full Factorial

Sotolon (4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one) is a powerful odorant usually pointed out as being responsible not only for the characteristic curry notes of the finest fortified wines but also for the off-flavour notes in prematurely oxidized white wines. Most methods reported in literature for quantifying sotolon in wines are quite laborious and use large volumes of organic solvents. Thus, in the present study, the development of a simple, fast, and environment-friendly method for the quantification of sotolon in fortified wine is herein presented. The proposed method uses a single-step liquid-liquid extraction followed by RP-LC-MS/MS and was optimized using a full factorial design. The method showed good linearity (R2 = 0.9999), intra- and interday precision lower than 10% RSD, recovery of about 95%, and high sensitivity (LOQ of 0.04 μg/L). The method was applied to analyse 44 fortified wines from different styles (from dry to sweet wines) and ages (3–115 years old), and it was found that it covers the concentration range usually found for this compound in this kind of alcoholic beverages, which was found to be within 6.3–810 μg/L. Thus, it can be concluded that this method can be used as an accurate tool for the rapid analysis of sotolon, since the early stages of its formation up to long ageing periods.

Reactive Dye Removal from Simulated Wastewater using Tetrabutyl Ammonium Bromide as an Extractant

2014 ◽  
Vol 67 (2) ◽  
Author(s):  
Norasikin Othman ◽  
Noor Sa’ida Nafisah Mohd Aziz ◽  
Norlisa Harruddin
Keyword(s):  
Dye Removal ◽  
Operation Time ◽  
Extraction Process ◽  
Liquid Extraction ◽  
Ammonium Bromide ◽  
Aquatic Life ◽  
Tetrabutyl Ammonium Bromide ◽  
Liquid Liquid Extraction ◽  
Tetrabutyl Ammonium ◽  
Remazol Red

Dyes caused serious environmental pollution and health problem in many ways. Many dyes have toxic effects on aquatic life and also on humans. Liquid-liquid extraction process is one of the alternatives for dye removal from wastewater. Removal of remazol red 3BS from simulated textile wastewater using tetrabutyl ammonium bromide has been studied at room temperature with total operation time of 18 hours. Several parameters have been studied such as pH, diluents, initial dye concentration, extractant concentration and stripping agents toward the extraction process of the dye. The results show only small effects of pH on the extraction percentage. The best diluent for the extraction is dichloromethane with the percentage of 98%. The percentage of extraction is maximum (97%) at 0.07M of TBAB concentration with the distribution ratio of D= 34.65. Salicylic acid in Na2CO3 with the ratio of 1:2 gives the highest percentage of stripping process. It shows a good performance for liquid-liquid extraction of remazol red 3BS for both removal and recovery processes.

scholarly journals On the Interaction of Doxorubicin with Oleate Ions: Fluorescence Spectroscopy and Liquid–Liquid Extraction Study

2007 ◽  
Vol 55 (7) ◽  
pp. 1006-1010 ◽  
Author(s):  
Emilie Munnier ◽  
Frédéric Tewes ◽  
Simone Cohen-Jonathan ◽  
Claude Linassier ◽  
Laurence Douziech-Eyrolles ◽  
...  
Keyword(s):  
Fluorescence Spectroscopy ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Extraction Study
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