scholarly journals Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist...Aminopterin

1974 ◽  
Vol 24 (5) ◽  
pp. 297-305 ◽  
Author(s):  
S. Farber
Keyword(s):  
Folic Acid ◽  
Acute Leukemia ◽  
Folic Acid Antagonist ◽  
Acid Antagonist ◽  
Leukemia In Children

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

1948 ◽  
Vol 238 (23) ◽  
pp. 787-793 ◽  
Author(s):  
Sidney Farber ◽  
Louis K. Diamond ◽  
Robert D. Mercer ◽  
Robert F. Sylvester ◽  
James A. Wolff
Keyword(s):  
Folic Acid ◽  
Acute Leukemia ◽  
Glutamic Acid ◽  
Folic Acid Antagonist ◽  
Acid Antagonist ◽  
Leukemia In Children

The Use of Methotrexate in Rheumatoid Arthritis

1985 ◽  
Vol 19 (5) ◽  
pp. 349-358 ◽  
Author(s):  
Peter W. Letendre ◽  
Douglas J. DeJong ◽  
Donald R. Miller
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trials ◽  
Folic Acid ◽  
Side Effects ◽  
Adverse Effects ◽  
Systemic Administration ◽  
Refractory Disease ◽  
Controlled Clinical Trials ◽  
Folic Acid Antagonist ◽  
Acid Antagonist

The use of methotrexate in rheumatoid arthritis is reviewed. Methotrexate, a folic acid antagonist, is sometimes employed in an attempt to symptomatically control patients whose disease does not respond adequately to conventional therapies. Systemic administration of 7.5–15 mg/wk in a “pulse” fashion appears to be effective without precipitating severe adverse effects. However, concern over potentially serious side effects and a lack of well-controlled clinical trials have limited its use to severe, refractory disease. Further studies are needed before its role in rheumatoid arthritis can justifiably be expanded.

Folic acid antagonist use before and during pregnancy and risk for selected birth defects

2020 ◽  
Vol 112 (18) ◽  
pp. 1526-1540
Author(s):  
Stephen M. Kerr ◽  
Samantha E. Parker ◽  
Allen A. Mitchell ◽  
Sarah C. Tinker ◽  
Martha M. Werler
Keyword(s):  
Folic Acid ◽  
Birth Defects ◽  
Folic Acid Antagonist ◽  
Acid Antagonist

Treatment of acute leukemia in children with and without folic acid antagonists

1952 ◽  
Vol 41 (4) ◽  
pp. 377-394 ◽  
Author(s):  
H.G. Poncher ◽  
H.A. Waisman ◽  
J.B. Richmond ◽  
O.A. Horak ◽  
L.R. Limarzi
Keyword(s):  
Folic Acid ◽  
Acute Leukemia ◽  
Folic Acid Antagonists ◽  
Leukemia In Children

Precipitation of Menstrual Bleeding in Monkeys by a Folic Acid Antagonist

Science ◽  
1950 ◽  
Vol 112 (2901) ◽  
pp. 147-147 ◽  
Author(s):  
M. X. Zarrow ◽  
F. L. Hisaw ◽  
H. A. Salhanick
Keyword(s):  
Folic Acid ◽  
Menstrual Bleeding ◽  
Folic Acid Antagonist ◽  
Acid Antagonist
Sign in / Sign up

Export Citation Format

Share Document