scholarly journals Sarcomatoid carcinoma of adrenal gland: a rare case report

2019 ◽  
Vol 10 (1) ◽  
pp. 73-75
Author(s):  
Israt Rezwana ◽  
Sourav Sarkar ◽  
Rushda Sharmin Binte Rouf ◽  
Sultana Marufa Shefin ◽  
SM Ashrafuzzaman

Adrenal sarcomatoid carcinoma (ASC) are very rare and aggressive malignant tumors of adrenal glands containing both epithelial (carcinomatous) and mesenchymal (sarcomatous) components. ASC presents a diagnostic challenge due to its atypical symptoms and histological patterns which influence treatment.At the time of diagnosis, a large percentage of patients are already at the metastatic stage and succumb within a few months. Here, we report a case of functional sarcomatoid carcinoma in right adrenal gland in a 37-year-old female, who presented with new onset hypertension. The patient underwent right sided adrenalectomy and she was alive at the time of writing the current report.To the best of our knowledge, ASC reported in literature to date showed only few patient presented with endocrine hypersecretion and only one patient presented with both hypertension and endocrine dysfunction. So, our case is the rarest among the rare. Birdem Med J 2020; 10(1): 73-75

2012 ◽  
Vol 02 (01) ◽  
pp. 45-47
Author(s):  
Shetty K. Padma ◽  
Harish S. Permi ◽  
C.N. Patil ◽  
Michelle Mathias

AbstractSarcomatoid carcinoma occurring in the small intestine is very rare. They can be monophasic or biphasic. We report a rare case of monophasic Sarcomatoid carcinoma of the small intestine in a 60 year old male patient. The tumor was an ulceronodular mass involving the ileum circumferentially. The tumor infiltrated the full thickness of the intestinal wall and the serosa of an adjacent loop of ileum. Microscopically, the tumor was composed of sheets of malignant spindle cells. The carcinomatous nature of the tumor was evident only after Immunohistochemistry. The diagnosis of sarcomatoid carcinoma should be considered in the differential diagnosis of malignant spindle cell tumor of small intestine and immunohistochemical stains are required for the correct diagnosis.


2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Vladimír Šámal ◽  
Tomáš Jirásek ◽  
Vít Paldus ◽  
Igor Richter ◽  
Ondřej Hes

Abstract Background Yolk sac tumor (YST) is a germ cell tumor. It is primarily located in the gonads but can also occur extragonadally (extragonadal yolk sac tumor - EGYST), most commonly in the pelvis, retroperitoneum or mediastinum. Only a few YSTs of the urachus have been described. Case report We present a rare case report of a 37-year-old male with episodes of macroscopic hematuria. The histological specimen obtained by transurethral resection showed a solid, and in some parts papillary infiltrative, high-grade tumor with numerous areas of marked nuclear atypia and clear invasion between the detrusor bundles. Glandular pattern has been observed in only minority of the tumor. Immunohistochemistry showed significant positivity for GPC3, SALL4 and cytokeratins AE1/AE3, while KRT7 and GATA3 were negative. We concluded that the biopsy findings were consistent with urothelial carcinoma with infrequent YST differentiation. In definitive surgical specimens we found a malignant epithelial, glandular and cystically arranged tumor of germinal appearance arising from urachus. The surrounding urothelium was free of invasive or in situ tumor changes. We reclassified the tumor as a urachal YST. Conclusion EGYST was suspected because glandular and hepatoid structures were found, but the presence of these structures should be verified by immunohistochemistry.


2020 ◽  
Vol 7 (11) ◽  
pp. C164-168
Author(s):  
Anusha Ganapathi ◽  
Thanka J ◽  
Lawrence D'Cruze ◽  
Barathi G ◽  
Natarajan K ◽  
...  

Paratesticular rhabdomyosarcomas (RMS) are very rare malignant tumors arising from the mesenchymal tissues of tunica, epididymis or spermatic cord. They present as painless hard masses in inguinoscrotal region, and large tumors can be mistaken for testicular tumors. They can spread to retroperitoneal lymph nodes or hematogenously metastasize to lung, bones and bone marrow. Here, we report a case of Embryonal RMS with spindle cell component presenting with painless scrotal mass and lung metastasis at initial diagnosis.


2016 ◽  
Vol 11 (5) ◽  
pp. 485-488
Author(s):  
Zakaria M. Al Hawsawi ◽  
Amal A. Alhejaili ◽  
Moeen Mohy Uddin ◽  
Mohamed E. Abdelkarim

2021 ◽  
Vol 2 (4) ◽  
pp. 01-03
Author(s):  
Vinay H G ◽  
Ramesh Reddy G ◽  
Shwetha R Chandra ◽  
Merin Mary

Masson’s tumor is a rare, benign, vascular lesion, commonly affecting the head, neck and peripheries. It is usually asymptomatic and can be confused with malignant tumors. We report a 56-year-old male who presented with a solitary swelling in the right side of neck which was clinically diagnosed as a benign cystic lesion, hence complete excision of the lesion was done. Histopathology demonstrated the papillary proliferation of endothelial cells, in favour of Masson’s tumor.


2013 ◽  
Vol 56 (3) ◽  
pp. 319 ◽  
Author(s):  
Sheng Zhang ◽  
SanYan Li ◽  
Xingfu Wang

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