C-reactive protein as a Predictor of Early Outcome Following Acute Myocardial Infarction

2021 ◽  
Vol 32 (2) ◽  
pp. 95-98
Author(s):  
Mukter Hossain Khan ◽  
Md Sakhawat Hossain ◽  
Md Daharul Islam ◽  
Roksana Malek ◽  
Md Lokman Hossain Tak

Background: Acute myocardial infarction (AMI) which constitutes STEMI & NSTEMI triggers an inflammatory reaction, which plays an important role in myocardial injury. An inflammatory marker such as C - reactive protein (CRP) reflects the extent of myocardial necrosis.Circulatory levels of Creactive protein (CRP) may be an independent risk factor for cardiovascular disease. Methods: An observational study was carried out in the department of Medicine and department of Cardiology of Faridpur Medical CollegeHospital, Faridpur from May 2012 to October 2012. One Hundred Patients were selected consecutively from acute Myocardial Infarction patients admitted in the department of medicine and Department of Cardiology of Faridpur Medical College Hospital. The sample was selected purposively. Quantitative value of CRP was done on first day of admission. Z test of proportion was done to analyze the data. Level of significance was < 0.05. Results: In this study, 84% of AMI had CRP level >6 mg/dl.86% patients had STEMI, and 14% patients had NSTEMI. Out of 86 patients with STEMI, 72 patients (83.72%) & out of 14 patients with NSTEMI, 12 patients (85.71%) had high CRP. Out of 72 STEMI patients with high CRP level, 22 patients (30.55%) & 6 patients (8.33%) were expired. Out of 12 NSTEMI patients with high CRP level, 2 patients (16.67%) developed left ventricular failure&no one was expired. STEMI was associated with worst outcome 30.55% vs 16.67% left ventricular failure and 8.33% vs 0% mortality rate. Conclusions: High CRP is a predictor of adverse early outcome in patients with acute coronary syndromes Bangladesh J Medicine July 2021; 32(2) : 95-98

2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Wael Rumaneh

Arterial hypertension is an independent predictor of acute myocardial infarction. Nowadays, plasma level of high-sensitive C-reactive protein is a marker of cardiovascular risk. The objective of the research was to evaluate plasma level of high-sensitive C-reactive protein in patients with acute myocardial infarction and arterial hypertension depending on myocardial remodeling type. Materials and methods. 130 patients with myocardial infarction (63 individuals with concomitant arterial hypertension and 67 individuals without it) were observed. Transthoracic echocardiogram was used. To evaluate plasma level of high-sensitive C-reactive protein the ELISA method was applied. Results. Plasma level of high-sensitive C-reactive protein in patients with acute myocardial infarction increased by 5.11 times compared to the control group: (10.67 [5.43; 12.89]) mg/l and (2.09 [1.40; 4.60]) mg/l, respectively (p<0.001). In myocardial infarction and arterial hypertension, this parameter increased by 6.57 times (to (13.73 [7.05; 15.17]) mg/l) (p<0.001), and by 1.27 times (p<0.05) as compared to patients without arterial hypertension. No differences in plasma level of high-sensitive C-reactive protein were detected in patients with different types of left ventricular remodeling.Conclusions. Acute myocardial infarction caused by high plasma level of high-sensitive C-reactive protein is severer in co-existent arterial hypertension. There are no differences in blood levels of high-sensitive C-reactive protein depending on the type of left ventricular remodeling.


1996 ◽  
Vol 79 (3_suppl) ◽  
pp. 1195-1202 ◽  
Author(s):  
Katija Čatipović-Veselica ◽  
Lidija Marošević ◽  
Vesna Ilakovac ◽  
Vjekoslav Amidžić ◽  
Damir Kozmar ◽  
...  

We examined Bortner scores for behavioral patterns and eight basic emotional dimensions named by Plutchik for patients with acute myocardial infarction who survived ventricular fibrillation and left ventricular failure. There were 70 patients, 48 men and 22 women ages 26 to 69 yr. ( M = 54, SD = 8), admitted to the coronary care unit within 24 hours of the onset of a long-lasting chest pain. Six patients survived an episode of ventricular fibrillation that occurred within 24 to 48 hours after their admission. 15 patients developed left ventricular failure and were in Killip Classes II and III. Patients with acute myocardial infarction and left ventricular failure had mean Bortner scores significantly lower than others with acute myocardial infarction and were classed as Type B behavior. There was no difference in Bortner scores between patients with ventricular fibrillation and others with acute myocardial infarction. Patients with acute myocardial infarction and left ventricular failure scored significantly higher on Timid than others with acute myocardial infarction. Patients with acute myocardial infarction and ventricular fibrillation scored significantly lower on Depressed and higher on Distrust than other patients with acute myocardial infarction. Our findings suggest that patients with ventricular fibrillation and low scores on Depressed have good hospital prognosis. They are more critical and tend to reject people and ideas more than patients with acute myocardial infarction. This study suggests that the way in which patients with acute myocardial infarction react to their infarction, in terms of eight basic emotions and test patterns, is dependent on the complications of myocardial infarction.


2007 ◽  
Vol 46 (11) ◽  
pp. 721-726
Author(s):  
Kazunobu Ishikawa ◽  
Hironori Kaneko ◽  
Masayoshi Oikawa ◽  
Taeko Ishii ◽  
Motoko Yoshikawa ◽  
...  

Circulation ◽  
1973 ◽  
Vol 47 (4) ◽  
pp. 729-735 ◽  
Author(s):  
DAVID T. KELLY ◽  
CESAR E. DELGADO ◽  
DEAN R. TAYLOR ◽  
BERTRAM PITT ◽  
RICHARD S. ROSS

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