scholarly journals To Compare the Efficacy of Tamsulosin, Solifenacin and Combination of Both in the Treatment of Double-J Stent Related Irritative Lower Urinary Tract Symptoms and Low Back Pain

2020 ◽  
Vol 23 (1) ◽  
pp. 48-51
Author(s):  
AHM Imrul Tareq ◽  
Md Sayedul Islam

Background: Stent-associated symptoms can have a significant impact on patient quality of life. Hematuria, urgency, frequency, dysuria, and both bladder and flank pain are the most prevalent symptoms related to indwelling ureteral stents. Among them irritative lower urinary tract symptoms and low back pain are more frequent. Despite the stent related symptoms, because of its importance stent is being kept in situ with varieties of medication. Several alpha-adrenergic blocker and antimuscarinic drugs are used to relief these symptoms like Tamsulosin, Solifenacin, Alphazosin etc. Both Tamsulosin and Solifenacin are not costly as use daily single dose. So combination of Tamsulosin and Solifenacin may act as a reliever of stent related symptoms and also cost effective. Methods and materials: For this purpose, a total of 126 patients having unilateral double-J ureteral stent for 7 days with stent related irritative LUTS and low back pain were included in this study. This hospital based prospective randomized clinical trial was carried out in Urology department of Bangabandhu Sheikh Mujib Medical University, Dhaka, during January 2014 to June 2015, to compare the irritative IPSS, improvement of quality of life score component of IPSS ,the low back pain score for double-J ureteral stent using Tamsulosin, Solifenacin and combination of both (Tamsulosin and Solifenacin) Results: Regarding the irritative sub group of International Prostate Symptom Score (IPSS) was observed during 2nd and 4th weeks follow up IPSS was significantly (p<0.05) higher in solifenacin and Tamsulosin group with compared to Tamsulosin+Solifenacin group. During 4th weeks follow up the mean quality of life (QOL) score was significantly (p<0.05) higher in solifenacin group and Tamsulosin group with compared to Tamsulosin+Solifenacin group.During 2nd weeks and 4th weeks follow up visual Analogue Pain Scale (VAPS) was significantly (p<0.05) higher in solifenacin group followed by Tamsulosin group and Tamsulosin+Solifenacin group. Conclusion: Combined use of Tamsulosin and Solifenacin is more effective than use of single drug (either Tamsulosin or Solifenacin) in the treatment of ureteral double-J stent related irritative LUTS and low back pain. Bangladesh Journal of Urology, Vol. 23, No. 1, January 2020 p.48-51

2010 ◽  
Vol 13 (04) ◽  
pp. 177-185 ◽  
Author(s):  
Suraj Kumar ◽  
Vijai P. Sharma ◽  
Anoop Aggarwal

Purpose: The present study was undertaken to find out the relationship among outcome variables as well as association between dependent variables with physical characteristics in low back pain (LBP) patients. Correlations between outcome variables [pain, back pressure changes (BPC), abdominal pressure changes (APC), walking, stairs climbing, stand ups, quality of life (QOL) and sexual frequency] of all LBP subjects before and after treatment were assessed. Regression analysis was used to estimate baseline BPC and APC of LBP subjects from their baseline demographic characteristics (age, height, waist circumference, systolic blood pressure, and pulse rate) and severity of pain. Methods: A total of 141 nonspecific chronic LBP patients were recruited. After baseline recording, all subjects were given trunk stabilization training for 20 regular days. After training, the follow-up was done at a gap of each 15 days up to 6 months (180 days). At the last follow-up session (180th day), the outcome variables were recorded again. Findings: The present study found an inverse relation between pain and muscle functions (BPC: r = -0.36; p < 0.01 and APC: r = -0.26; p < 0.01). This study also showed that BPC was more inversely related with the pain than APC. Conclusions: This study concludes that physical strength (BPC and APC) of LBP subjects is more closely associated with the pain than the functional ability (walking, stairs climbing and stand ups). This study also estimated (baseline or before treatment) BPC and APC in LBP subjects from their physical characteristics and pain severity.


Spine ◽  
2012 ◽  
Vol 37 (22) ◽  
pp. 1899-1903 ◽  
Author(s):  
Tsutomu Akazawa ◽  
Shohei Minami ◽  
Toshiaki Kotani ◽  
Tetsuharu Nemoto ◽  
Takana Koshi ◽  
...  

2002 ◽  
Vol 27 (3) ◽  
pp. 110-116 ◽  
Author(s):  
Ragnhild Raak ◽  
Karin Wikblad ◽  
Anders Raak ◽  
Marianne Carlsson ◽  
Lis Karin Wahren

2021 ◽  
Vol 7 (2) ◽  
pp. 67-74
Author(s):  
Sajjad Saadat ◽  
◽  
Mozaffar Hosseininezhad ◽  
Seyed Sepehr Khatami ◽  
Reza Ghasemi Jobaneh ◽  
...  

Background and Aim: Chronic low Back Pain (CLBP) is one of the most common musculoskeletal disorders with possible psychological consequences for the patients. This study aimed to review all evidence on the effectiveness of psychological interventions in improving the mental status of people with CLBP and providing recommendations for future therapeutic interventions. Methods and Materials/Patients: This systematic review was conducted on the articles published from January 2010 to December 2020. The keywords included “psychology”, “intervention”, “low back pain”, “chronic disease”, “quality of life”, “empowerment”, “psychotherapy”, “psychological interventions”, “clinical trials”, and “randomized clinical trials” in the indexing databases of Magiran, PubMed, Scopus, and Google Scholar. Of the total 1740 articles found, 14 articles were selected for review. Results: The results showed that Cognitive-Behavioral Therapy (CBT) and its combination therapies with mindfulness techniques played an influential role in improving psychological status and quality of life, and reducing pain perception in CLBP patients. The lack of RCT (randomized controlled trial) research and follow-up to assess long-term outcomes are the main limitations of the studies conducted in Iran. Conclusion: It is recommended that psychological interventions be considered alongside medical therapies to improve CLBP patients’ adjustment to chronic condition and their quality of life. Researchers and therapists should consider treatment programs based on RCT plans and long-term follow-up.


2021 ◽  
Vol 10 (24) ◽  
pp. 5961
Author(s):  
Hiroyuki Inose ◽  
Tsuyoshi Kato ◽  
Shinichi Shirasawa ◽  
Shinji Takahashi ◽  
Masatoshi Hoshino ◽  
...  

To date, it is still unclear how fresh osteoporotic vertebral fractures (OVFs) affect the patient’s quality of life and low back pain during a follow-up period of more than 1 year. In the previous trial, women with fresh OVF were randomized to rigid or soft brace for 12 weeks, then both groups were followed for the subsequent 48 weeks. In women completing this trial at our affiliated hospitals, we conducted a follow-up study to investigate the long-term course of an acute vertebral fracture in terms of pain and quality of life. When comparing visual analog scale scores for low back pain and European Quality of Life-5 Dimensions Questionnaire scores between consecutive time points, a significant difference was found between 0 and 12 weeks, but not between 12 and 48 weeks or between 48 weeks and final follow-up. A total 25% had residual low back pain at the final follow-up. A stepwise logistic regression analysis identified age and previous vertebral fracture as predictors of residual low back pain at the final follow-up. Therefore, the degree of low back pain and impairment of the quality of life improved by 12 weeks after injury and did not change thereafter until a mean follow-up of 5.3 years.


2017 ◽  
Vol 17 (1) ◽  
pp. 22-29 ◽  
Author(s):  
Bo Nyström ◽  
Birgitta Gregebo ◽  
Adam Taube ◽  
Stig-Olof Almgren ◽  
Birgitta Schillberg ◽  
...  

AbstractBackgroundIt has been reported that in 13-32% of patients with chronic low back pain, the pain may originate in the sacroiliac (SI) joints. When treatment of these patients with analgesics and physiotherapy has failed, a surgical solution may be discussed. Results of such surgery are often based on small series, retrospective analyses or studies using a minimal invasive technique, frequently sponsored by manufacturers.PurposeTo report the clinical outcome concerning pain, function and quality of life following anterior arthrodesis in patients presumed to have SI joint pain using validated questionnaires pre- and post-operatively. An additional aim was to describe the symptoms of the patients included and the preoperative investigations performed.Material and methodsOver a 6 year period we treated 55 patients, all women, with a mean age of 45 years (range 28-65) and a mean pelvic pain duration of 9.1 years (range 2-30). The pain started in connection with minor trauma in seven patients, pregnancy in 20 and unspecified in 28. All patients had undergone long periods of treatment including physiotherapy, manipulation, needling, pelvic belt, massage and chiropractic without success, and 15 had been operated for various spinal diagnoses without improvement. The patients underwent thorough neurological investigation, plain X-ray and MRI of the spine and plain X-ray of the pelvis. They were investigated by seven clinical tests aimed at indicating pain from the SI joints. In addition, all patients underwent a percutaneous mechanical provocation test and extra-articular local anaesthetic blocks against the posterior part of the SI joints. Before surgery all patients answered the generic Short-Form-36 (SF-36) questionnaire, the disease specific Balanced Inventory for Spinal Disorders (BIS) questionnaire and rated their level of pelvic and leg pain (VAS, 0-100). At follow-up at a mean of 2 years 49 patients completed the same questionnaires (89%).ResultsAt follow-up 26 patients reported a lower level of pelvic pain than before surgery, 16 the same level and six a higher level. Applying Svensson’s method RPpelvic pain = 0.3976, with 95% CI (0.2211, 0.5740) revealed a statistically significant systematic improvement in pelvic pain. At follow-up 28 patients reported a higher quality of life and 26 reported sleeping better than pre-operatively. In most patients the character of the pelvic pain was dull and aching, often accompanied by a stabbing component in connection with sudden movements. Referred pain down the leg/s even to the feet and toes was noted by half of the patients and 29 experienced frequency of micturition.ConclusionsIt is apparent that in some patients the SI joints may cause long-term pain that can be treated by arthrodesis. We speculate that continued pain despite a healed arthrodesis may be due to persistent pain from adjacent ligaments. The next step should be a prospective randomized study comparing posterior fusion and ligament resection with non-surgical treatment.ImplicationsAnterior arthrodesis can apparently relieve pain in some patients with presumed SI joint pain. The problem is how to identify these patients within the low back pain group.


2020 ◽  
Vol 34 (7) ◽  
pp. 948-959 ◽  
Author(s):  
Guillermo A Matarán-Peñarrocha ◽  
Inmaculada Carmen Lara Palomo ◽  
Eduardo Antequera Soler ◽  
Esther Gil-Martínez ◽  
Manuel Fernández-Sánchez ◽  
...  

Objective: To compare the effectiveness of supervised physical therapy program versus non-supervised on pain, functionality, fear of movement and quality of life in patients with non-specific chronic low back pain. Design: A randomized double-blind clinical trial. Setting: Clinical outpatient unit; home. Subjects: A total of 64 participants with non-specific chronic low back pain were randomized into either supervised exercise group ( n = 32) or non-supervised home exercise group ( n = 32). Interventions: The supervised group was treated with therapy exercises (strengthen lumbopelvic musculature), while the non-supervised received an informative session of the exercises, which were performed un-supervised at home. Both groups received three weekly sessions for eight weeks. Main Measures: Pain, disability, fear of movement, quality of life, trunk muscle endurance and trunk anteflexion motion were assessed at baseline, two, and six months of follow-up. Results: Although analysis of variance (ANOVA) test showed statistically significant differences between groups for pain ( P = 0.028; supervised: 2.5 ± 2.1; non-supervised: 3.5 ± 1.5) and disability for Roland–Morris Disability Questionnaire ( P = 0.004; supervised: 3.1 ± 2.2; non-supervised: 5.1 ± 3.0) and for Oswestry Disability Index ( P = 0.034; supervised: 14.5 ± 7.1; non-supervised: 19.2 ± 10.0) at 8 weeks immediately posttreatment, there were no differences between the groups in patient-rated pain, functionality, fear of movement and quality of life at six months of follow-up. Conclusion: Patients with chronic low back pain who received supervised exercise showed more improvement in both the short and long term in all patient-rated outcomes over the non-supervised group, but the differences were small and not clinically significant.


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