scholarly journals John W Kirklin: The Greatest Scientific Cardiac Surgeon of the Century

2021 ◽  
Vol 14 (1) ◽  
pp. 93-96
Author(s):  
- Md Anisuzzaman ◽  
Nazmul Hosain
Keyword(s):  
Heart Surgery ◽  
Correct Diagnosis ◽  
Open Heart Surgery ◽  
John Webster ◽  
Open Heart ◽  
Prolific Author ◽  
The Bible ◽  
Cardiac Surgeon ◽  
The Subject ◽  
Cardiothoracic Surgeon

John Webster Kirklin was an American cardiothoracic surgeon, prolific author and medical educator who is best remembered for refining John Gibbon’s heart-lung bypass machine via a pump-oxygenator to make feasible under direct vision routine open-heart surgery. His other advances, on which success of heart surgeries depends, including teamwork, developments in establishing the correct diagnosis before surgery and progress in computerized intensive care unit monitoring after open heart surgery. Wayne Miller refers to Dr Kirklin in the 1970s as “arguably the best practicing open heart surgeon anywhere. He was one of cardiac surgery’s most accomplished researchers, a scientist whose mind was sometimes compared, flatteringly, to a computer.” John W Kirklin and Brian G Barratt-Boyes drafted the book ‘Cardiac Surgery’, which is considered as the Bible of the subject. Cardiovasc j 2021; 14(1): 93-96

Establishing a sustainable open heart surgery programme in Nigeria, a low-income country: which is the best model?

2019 ◽  
Vol 29 (12) ◽  
pp. 1489-1493 ◽  
Author(s):  
Ikechukwu A. Nwafor ◽  
John C. Eze ◽  
Maureen N. Nwafor ◽  
Keyword(s):  
Low Income ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Teaching Hospitals ◽  
Open Heart ◽  
Political Climate ◽  
Low Income Country ◽  
Fiscal Management ◽  
Cardiac Surgeon ◽  
Year 2000

AbstractBackground:In any country, the development of open heart surgery programme parallels stable political climate, economic growth, good leadership, and prudent fiscal management. This is lacking in a country like Nigeria without a functional cardiac hospital.Objective:To review and compare the various models being adopted towards establishing a sustainable open heart surgery programme in Nigeria.Materials and Methods:For ethnic and cultural reasons, Nigeria is divided into six geopolitical regions. Each region has one or more Federal Teaching Hospitals including medical centres. The hospitals have trained cardiothoracic surgeons and cardiologists as well as other auxiliary staff. After attainment of democratic rule in 1999, individual hospitals have devised various models to establish sustainable open heart surgery programme. The number of hospitals in each region, the models devised, and the limitations including the outcome were studied and analysed.Results:Each geopolitical zone has about three to four centres, either public or private, trying to establish the programme. There are six different models. Each centre has been trying the different models since the year 2000. The oldest of the model is cardiac mission and the newest is employment of highly skilled retired expatriate consultant cardiac surgeon to help develop the local team. Inadequate funds, lack of governmental support, and brain drain syndrome have largely affected the programme.

scholarly journals Open Hart Surgery Experience of a High Volume Center During Pandemic

2021 ◽  
Author(s):  
Kemal Karaarslan ◽  
Ayşe Gül Kunt ◽  
Burçin Abud
Keyword(s):  
Cardiac Disease ◽  
Heart Surgery ◽  
Cardiovascular Surgery ◽  
Open Heart Surgery ◽  
Median Sternotomy ◽  
High Volume ◽  
Healthcare Team ◽  
Open Heart ◽  
High Volume Center ◽  
Cardiac Surgeon

Objective: The aim of the study is to report the results of open heart surgery performed during the pandemic. Methods: One hundred eighty-five symptomatic patients were operated under a median sternotomy with a cardiopulmonary bypass in our pandemic hospital. They were all outpatient and were COVID-negative and strict precautions were taken. Results: 185 patients were referred to cardiovascular surgery for several type of cardiac operation. All patients were symptomatic due to primary cardiac disease. In-hospital mortality rate was seven times higher in those with Covid-19 (22.2%) while the non Covid-19 patients had a rate of (3.4%) (p<0.0001). Conclusion: Cardiac surgery is inevitable in symptomatic patients and can be done even with the risk of transmission and death. The patient, cardiac surgeon, and healthcare team should be aware of the ongoing contamination time.

The Hemostatic Mechanism after Open-Heart Surgery

1978 ◽  
Vol 39 (02) ◽  
pp. 474-487 ◽  
Author(s):  
E R Cole ◽  
F Bachmann ◽  
C A Curry ◽  
D Roby
Keyword(s):  
Extracorporeal Circulation ◽  
Heart Surgery ◽  
Polyacrylamide Gel Electrophoresis ◽  
Open Heart Surgery ◽  
Coagulation System ◽  
Open Heart ◽  
Time Activity ◽  
Post Surgery ◽  
Plasma Fractions ◽  
The Mean

SummaryA prospective study in 13 patients undergoing open-heart surgery with extracorporeal circulation revealed a marked decrease of the mean one-stage prothrombin time activity from 88% to 54% (p <0.005) but lesser decreases of factors I, II, V, VII and X. This apparent discrepancy was due to the appearance of an inhibitor of the extrinsic coagulation system, termed PEC (Protein after Extracorporeal Circulation). The mean plasma PEC level rose from 0.05 U/ml pre-surgery to 0.65 U/ml post-surgery (p <0.0005), and was accompanied by the appearance of additional proteins as evidenced by disc polyacrylamide gel electrophoresis of plasma fractions (p <0.0005). The observed increases of PEC, appearance of abnormal protein bands and concomitant increases of LDH and SGOT suggest that the release of an inhibitor of the coagulation system (similar or identical to PIVKA) may be due to hypoxic liver damage during extracorporeal circulation.

Blood Coagulation Studies and Extracorporeal Circulation in Man

1967 ◽  
Vol 18 (03/04) ◽  
pp. 634-646 ◽  
Author(s):  
N Thurnherr
Keyword(s):  
Blood Coagulation ◽  
Extracorporeal Circulation ◽  
Blood Clotting ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Fibrinolytic System ◽  
Open Heart ◽  
Clotting Factors ◽  
Blood Clotting Factors

SummaryBlood clotting investigations have been executed in 25 patients who have undergone open heart surgery with extracorporeal circulation. A description of alterations in the activity of blood clotting factors, the fibrinolytic system, prothrombin consumption and platelets during several phases of the operation is given.

Open heart surgery in patients with cold agglutinins: Is the fear justified?

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
N Madershahian ◽  
T Wittwer ◽  
J Strauch ◽  
J Wippermann ◽  
UFW Franke ◽  
...  
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Cold Agglutinins

Evaluation of Positive Inotropic Drug Effects on Thyroid Hormone Levels after Open Heart Surgery

2015 ◽  
Vol 16 (2) ◽  
pp. 78
Author(s):  
Umit Kervan ◽  
Anil Ozen ◽  
Utku Unal ◽  
Irfan Tasoglu ◽  
Mahmut Mustafa Ulas ◽  
...  
Keyword(s):  
Drug Therapy ◽  
Thyroid Hormone ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Inotropic Drug ◽  
Hormone Levels ◽  
Inotropic Drugs ◽  
Positive Inotropic Drug ◽  
Thyroid Hormone Levels

<p><b>Objective:</b> The aim of this study was to examine the effects of positive inotropic drugs, including adrenaline, dopamine, and dobutamine on thyroid hormone levels following open heart surgery.</p><p><b>Methods:</b> We analyzed free thyroid hormones (FT3 and FT4) and thyroid-stimulating hormones (TSH) in 200 consecutive patients undergoing open heart surgery. Patients were divided into 5 groups according to the inotropic drug administration as follows: Group A (n = 46) received dopamine alone; Group B (n = 40), dopamine and dobutamine; Group C (n = 36), dopamine, dobutamine, and adrenaline; Group D (n = 32), adrenaline alone; and Group E (n = 46), placebo. Procedural factors affecting thyroid hormones were recorded and included cardiopulmonary bypass (CPB) time, cross-clamping time, degree of hypothermia, and the duration and doses of positive inotropic drugs. Blood samples for hormone assays were collected before initiation of inotropic drug therapy (baseline) and postoperatively at 24, 72, and 120 hours after drug therapy.</p><p><b>Results:</b> FT3, FT4, and TSH levels at baseline were similar in all groups. Although there was a trend showing very slight increases in thyroid hormone levels from baseline to the 24th, 72nd, and 120th postoperative hours after drug therapy, these changes were not significant, and there were also no significant differences between the groups. There was also no significant statistical difference in CPB time, cross-clamping time, degree of hypothermia, and duration and doses of positive inotropic drugs between groups.</p><p><b>Conclusion:</b> Although thyroid hormone levels were affected by positive inotropic drug usage after open heart surgery, this effect was not significant and thyroid hormone levels remained within normal ranges.</p>

Electrocardiographic Changes in Open Heart Surgery under Hypothermia

1960 ◽  
Vol 1 (4) ◽  
pp. 397-407
Author(s):  
Hiroshi SATAKE ◽  
Hiromichi TSUCHIOKA ◽  
Osamu MINAMIKAWA ◽  
Toshihito MAEHARA ◽  
Takeshi SHIMIZU
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Electrocardiographic Changes
Sign in / Sign up

Export Citation Format

Share Document