scholarly journals Idiopathic Thrombocytopenic Purpura with Intracranial Haemorrhage and Menorrhagia

2017 ◽  
Vol 35 (2) ◽  
pp. 97-99
Author(s):  
Suchanda Das ◽  
Bidhan Roy Chowdhury ◽  
Rokeya Begum
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Intracranial Hemorrhage ◽  
Clinical Importance ◽  
Invasive Procedure ◽  
Limited Effect ◽  
Thrombocytopenic Purpura ◽  
Aggressive Management ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
The Individual

A rare and life threatening complication of idiopathic thrombocytopenic purpura is intracranial hemorrhage ( ICH) and is the leading reported cause of death. The other important manifestation of ITP is menorrhagia. There are a variety of different causes of menorrhagia and gynecological evaluation is essential to tailor management to the individual patient to prevent unnecessary invasive procedure which may have limited effect. A 25 years old female para-2+0 presented with menorrhagia,severe excruciating headache,easy bruising, ecchymosis and petechialhemorrhage. After all investigation clinical evaluation it was diagnosed as a case of ITP with intracranial hemorrhage and menorrhagia. An intracranial hemorrhage is the most dreaded complication of ITP it is essential toprecede an early diagnosis, prompt and aggressive management and optimizing the management of acute menorrhagia remains of clinical importance due to life threatening nature of the condition.J Bangladesh Coll Phys Surg 2017; 35(2): 97-99

scholarly journals Endoscopic stent insertion for anastomotic leakage following oesophagectomy

2013 ◽  
Vol 95 (1) ◽  
pp. 43-47 ◽  
Author(s):  
M Schweigert ◽  
N Solymosi ◽  
A Dubecz ◽  
RJ Stadlhuber ◽  
H Muschweck ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Stent Implantation ◽  
Fatal Outcome ◽  
Invasive Procedure ◽  
High Volume ◽  
Primary Treatment ◽  
Stent Insertion ◽  
Endoscopic Stent ◽  
Life Threatening ◽  
Life Threatening Complication

Introduction Intrathoracic anastomotic leakage following oesophagectomy is a crushing condition. Until recently, surgical re-exploration was the preferred way of dealing with this life threatening complication. However, mortality remained significant. We therefore adopted endoscopic stent implantation as the primary treatment option. The aim of this study was to investigate the feasibility and results of endoscopic stent implantation as well as potential hazards and pitfalls. Methods Between January 2004 and December 2011, 292 consecutive patients who underwent an oesophagectomy at a single high volume centre dedicated to oesophageal surgery were included in this retrospective study. Overall, 38 cases with anastomotic leakage were identified and analysed. Results A total of 22 patients received endoscopic stent implantation as primary treatment whereas a rethoracotomy was mandatory in 15 cases. There were no significant differences in age, frequency of neoadjuvant therapy or ASA grade between cases with and without a leak. However, patients with a leak were five times more likely to have a fatal outcome (odds ratio: 5.10, 95% confidence interval: 2.06–12.33, p<0.001). Stent migration occurred but endoscopic reintervention was feasible. In 17 patients (77%) definite closure and healing of the leak was achieved, and the stent was removed subsequently. Two patients died owing to severe sepsis despite sufficient stent placement. Moreover, stent related aortic erosion with consecutive fatal haemorrhage occurred in three cases. Conclusions Stent implantation for intrathoracic oesophageal anastomotic leaks is feasible and compares favourably with surgical re-exploration. It is an easily available, minimally invasive procedure that may reduce leak related mortality. However, it puts the already well-known risk of stent-related vascular erosion on the spot. Awareness of this life threatening complication is therefore mandatory.

scholarly journals Idiopathic Thrombocytopenic Purpura Misdiagnosed as Hereditary Angioedema

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Michelle Fog Andersen ◽  
Anette Bygum
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Hereditary Angioedema ◽  
Care Setting ◽  
Autosomal Dominant ◽  
Bleeding Episode ◽  
Genetic Disorder ◽  
Acute Attack ◽  
Autosomal Dominant Trait ◽  
Thrombocytopenic Purpura ◽  
Life Threatening

Hereditary angioedema is a rare, but potentially life-threatening genetic disorder that results from an autosomal dominant trait. It is characterized by acute, recurrent attacks of severe local edema, most commonly affecting the skin and mucosa. Swelling in hereditary angioedema patients does however not always have to be caused by angioedema but can relate to other concomitant disorders. In this report we are focusing on misdiagnosis in a patient with known hereditary angioedema, whose bleeding episode caused by idiopathic thrombocytopenic purpura was mistaken for an acute attack of hereditary angioedema. The case illustrates how clinicians can have difficulties in handling patients with rare diseases, especially in the emergency care setting.

scholarly journals Maternal and Neonatal Idiopathic Thrombocytopenic Purpura

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Kendall Steadmon
Keyword(s):  
Autoimmune Disease ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Rare Event ◽  
Thrombocytopenic Purpura ◽  
Benign Condition ◽  
Lasting Effect ◽  
Autoimmune Destruction ◽  
Life Threatening ◽  
Newborn Child ◽  
Pregnant Mothers

Immune thrombocytopenic (ITP) is an autoimmune disease that affects 9.5/100,000 adults in the population.1 It is characterized by autoimmune destruction of platelets leading to potentially life-threatening thrombocytopenia. About 7% of pregnant mothers are affected by thrombocytopenia with 1 to 10 per 10,000 mothers being affected with ITP. Studies have shown that ITP is generally a benign condition in the birthing mother and rarely has a long-lasting effect on the newborn child.2 In the rare event that the newborn is severely affected, treatment is required. We present a case of ITP in both a mother and her newborn.

scholarly journals Fetal Hydrocephalus following Intracranial Hemorrhage secondary to Maternal Idiopathic Thrombocytopenic Purpura : A Case Report

2009 ◽  
Vol 18 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Hidemichi Ito ◽  
Yohtaro Sakakibara ◽  
Jun Hiramoto ◽  
Hiroshi Yoshida ◽  
Kouji Sakai ◽  
...  
Keyword(s):  
Case Report ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Intracranial Hemorrhage ◽  
Thrombocytopenic Purpura ◽  
Fetal Hydrocephalus
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