Head Trauma and Intracranial Hemorrhage in Children With Idiopathic Thrombocytopenic Purpura

A rare and life threatening complication of idiopathic thrombocytopenic purpura is intracranial hemorrhage ( ICH) and is the leading reported cause of death. The other important manifestation of ITP is menorrhagia. There are a variety of different causes of menorrhagia and gynecological evaluation is essential to tailor management to the individual patient to prevent unnecessary invasive procedure which may have limited effect. A 25 years old female para-2+0 presented with menorrhagia,severe excruciating headache,easy bruising, ecchymosis and petechialhemorrhage. After all investigation clinical evaluation it was diagnosed as a case of ITP with intracranial hemorrhage and menorrhagia. An intracranial hemorrhage is the most dreaded complication of ITP it is essential toprecede an early diagnosis, prompt and aggressive management and optimizing the management of acute menorrhagia remains of clinical importance due to life threatening nature of the condition.J Bangladesh Coll Phys Surg 2017; 35(2): 97-99

Download Full-text

Idiopathic Thrombocytopenic Purpura with Intracranial Hemorrhage and Vitreous Hemorrhage

Clinical Pediatrics ◽

10.1177/000992289002901210 ◽

1990 ◽

Vol 29 (12) ◽

pp. 725-728 ◽

Cited By ~ 10

Author(s):

Carl A. Frankel ◽

Domenic J. Pastore

Keyword(s):

Idiopathic Thrombocytopenic Purpura ◽

Intracranial Hemorrhage ◽

Vitreous Hemorrhage ◽

Thrombocytopenic Purpura

Download Full-text

Fetal Hydrocephalus following Intracranial Hemorrhage secondary to Maternal Idiopathic Thrombocytopenic Purpura : A Case Report

Japanese Journal of Neurosurgery ◽

10.7887/jcns.18.56_1 ◽

2009 ◽

Vol 18 (1) ◽

pp. 56-61 ◽

Cited By ~ 1

Author(s):

Hidemichi Ito ◽

Yohtaro Sakakibara ◽

Jun Hiramoto ◽

Hiroshi Yoshida ◽

Kouji Sakai ◽

...

Keyword(s):

Case Report ◽

Idiopathic Thrombocytopenic Purpura ◽

Intracranial Hemorrhage ◽

Thrombocytopenic Purpura ◽

Fetal Hydrocephalus

Download Full-text

Idiopathic Thrombocytopenic Purpura and Intracranial Hemorrhage

PEDIATRICS ◽

10.1542/peds.67.4.570 ◽

1981 ◽

Vol 67 (4) ◽

pp. 570-571 ◽

Cited By ~ 1

Author(s):

William Krivit ◽

Douglas Tate ◽

James G. White ◽

Leslie L. Robison

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Idiopathic Thrombocytopenic Purpura ◽

Intracranial Hemorrhage ◽

Personal Experience ◽

Platelet Transfusion ◽

Severe Complication ◽

Thrombocytopenic Purpura ◽

Benign Disorder ◽

Effective Manner

In this issue of Pediatrics (p 453) Drs Woerner, Abildgaard, and French present three new cases of intracranial hemorrhage in children with idiopathic thrombocytopenic purpura (ITP) and review the data of 15 previously reported cases. The authors discuss the care and management of this most severe complication of an otherwise mainly benign disorder and emphasize that, although it occurs most commonly in the early days after diagnosis, intracranial hemorrhage can occur in patients with ITP at nearly any time after onset. Their review and personal experience indicate that, even if CNS symptoms are already present, the alert physician with the present armamentarium of computed tomography (CT) scan, platelet transfusion, and splenectomy should be able to prevent permanent Sequelae in the majority of patients treated in an effective manner.

Download Full-text

Intracranial Hemorrhage in Children with Idiopathic Thrombocytopenic Purpura

PEDIATRICS ◽

10.1542/peds.67.4.453 ◽

1981 ◽

Vol 67 (4) ◽

pp. 453-460 ◽

Cited By ~ 1

Author(s):

Sarah Joan Woerner ◽

Charles F. Abildgaard ◽

Barry N. French

Keyword(s):

Posterior Fossa ◽

Idiopathic Thrombocytopenic Purpura ◽

Intracranial Hemorrhage ◽

Favorable Outcome ◽

Antiplatelet Drugs ◽

Thrombocytopenic Purpura ◽

Neurosurgical Procedure ◽

Diagnosis And Management ◽

Brainstem Compression

Intracranial hemorrhage is a rare but lifethreatening complication of childhood idiopathic thrombocytopenic purpura. We present three cases of this complication encountered at our institution, in addition to a tabulation of 15 previously reported cases. Prevention, diagnosis, and management of intracranial hemorrhage in idiopathic thrombocytopenic purpura are discussed. The importance of avoidance of antiplatelet drugs as well as the significance of the location of the intracranial hemorrhage are emphasized. Posterior fossa hemorrhages are especially dangerous because of the possibility of rapid cerebellar herniation and brainstem compression. Management of intracranial hemorrhage should be prompt and aggressive, and splenectomy should always be performed prior to any neurosurgical procedure. It is encouraging that 11 of 18 patients had a favorable outcome.

Download Full-text