scholarly journals Life threatening complication following Vascath insertion in a patient with immune thrombocytopenic purpura (ITP)

2016 ◽  
Vol 4 (1) ◽  
pp. 50-54
Author(s):  
Laura Beard ◽  
Mark Roper ◽  
Max Hodges
Keyword(s):  
Immune Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura ◽  
Life Threatening ◽  
Life Threatening Complication

scholarly journals Idiopathic Thrombocytopenic Purpura with Intracranial Haemorrhage and Menorrhagia

2017 ◽  
Vol 35 (2) ◽  
pp. 97-99
Author(s):  
Suchanda Das ◽  
Bidhan Roy Chowdhury ◽  
Rokeya Begum
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Intracranial Hemorrhage ◽  
Clinical Importance ◽  
Invasive Procedure ◽  
Limited Effect ◽  
Thrombocytopenic Purpura ◽  
Aggressive Management ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
The Individual

A rare and life threatening complication of idiopathic thrombocytopenic purpura is intracranial hemorrhage ( ICH) and is the leading reported cause of death. The other important manifestation of ITP is menorrhagia. There are a variety of different causes of menorrhagia and gynecological evaluation is essential to tailor management to the individual patient to prevent unnecessary invasive procedure which may have limited effect. A 25 years old female para-2+0 presented with menorrhagia,severe excruciating headache,easy bruising, ecchymosis and petechialhemorrhage. After all investigation clinical evaluation it was diagnosed as a case of ITP with intracranial hemorrhage and menorrhagia. An intracranial hemorrhage is the most dreaded complication of ITP it is essential toprecede an early diagnosis, prompt and aggressive management and optimizing the management of acute menorrhagia remains of clinical importance due to life threatening nature of the condition.J Bangladesh Coll Phys Surg 2017; 35(2): 97-99

scholarly journals “Uber-Trim” Causes Immune Thrombocytopenic Purpura: A Life Threatening Case Report

CHEST Journal ◽  
2016 ◽  
Vol 150 (4) ◽  
pp. 392A ◽  
Author(s):  
Gautam Sikka ◽  
Aditya Gupta ◽  
Moses Bachan ◽  
Zinobia Khan
Keyword(s):  
Case Report ◽  
Immune Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura ◽  
Life Threatening

scholarly journals Tranexamic Acid in a Case Report of Life-threatening Nontraumatic Hemorrhage in Immune Thrombocytopenic Purpura

2020 ◽  
Vol 4 (3) ◽  
pp. 421-423
Author(s):  
Melanie Randall ◽  
Jason Nurse ◽  
Karan Singh
Keyword(s):  
Case Report ◽  
Tranexamic Acid ◽  
Immune Thrombocytopenic Purpura ◽  
The Body ◽  
Thrombocytopenic Purpura ◽  
Increased Risk ◽  
Life Threatening ◽  
Traditional Therapies ◽  
Effective Adjunct ◽  
Uncontrolled Bleeding

Introduction: Immune thrombocytopenic purpura (ITP) is an autoimmune-mediated disorder in which the body produces antibodies that destroy platelets, causing an increased risk of bleeding and bruising. Tranexamic acid (TXA) is a medication that prevents clot breakdown and is used to treat uncontrolled bleeding. Case Report: We present the case of an 11-year-old female with significant epistaxis and hypotension in the emergency department. Traditional therapies were initiated; however, the patient continued to have bleeding and remained hypotensive, so intravenous TXA was given. The patient’s bleeding then resolved. Conclusion: TXA may be a safe and effective adjunct to traditional therapies for the treatment of life-threatening hemorrhage in ITP patients.

scholarly journals Severe immune thrombocytopenic purpura in critical COVID-19: a case report

2020 ◽  
Author(s):  
Valérie Lévesque ◽  
Émilie Milaire ◽  
Daniel Corsilli ◽  
Benjamin Rioux-Massé ◽  
François Martin Carrier
Keyword(s):  
Immune Thrombocytopenic Purpura ◽  
Immune Thrombocytopenia ◽  
Clinical Manifestations ◽  
High Dose ◽  
New Disease ◽  
First Line ◽  
Thrombocytopenic Purpura ◽  
High Dose Dexamethasone ◽  
Life Threatening ◽  
Hematological Manifestations

Abstract Purpose: COVID-19 is a new disease with many undescribed clinical manifestations. Material and methods: We report herein a case of severe immune thrombocytopenic purpura (ITP) in a critical COVID-19 patient.Results: A patient presented a severe episode of immune thrombocytopenia (< 10 x 109/L) 20 days after admission for a critical COVID-19. This thrombocytopenia was associated with a life-threatening bleeding. Response to first-line therapies was delayed as it took up to 13 days after initiation of intravenous immunoglobulin and high dose dexamethasone to observe an increase in platelet count. Conclusion: COVID-19 may be associated with late presenting severe ITP. Such ITP may also be relatively resistant to first-line agents. Hematological manifestations of COVID-19, such as the ones associated with life-threatening bleeding, must be recognized.

Dapsone hypersensitivity syndrome-rare complication of dapsone therapy

2017 ◽  
Vol 5 (4) ◽  
pp. 1700
Author(s):  
Muzaffar Maqbool ◽  
Fayaz A. Wani ◽  
Rakesh K. Koul ◽  
Parvaiz A. Shah
Keyword(s):  
Female Student ◽  
Drug Withdrawal ◽  
Rare Complication ◽  
Hypersensitivity Syndrome ◽  
Favourable Outcome ◽  
Glucocorticoid Therapy ◽  
Thrombocytopenic Purpura ◽  
Systemic Glucocorticoid ◽  
Life Threatening ◽  
Life Threatening Complication

Among several other adverse effects of dapsone therapy, dapsone hypersensitivity syndrome is extremely rare but most life-threatening complication. Here we report a case of severe dapsone hypersensitivity syndrome in a 27-year-old female student diagnosed as immune thrombocytopenic purpura on dapsone therapy who was admitted with remittent fever, lymphadenopathy and skin rash and was managed successfully with drug withdrawal and systemic glucocorticoid therapy. The idea of reporting this case is to recognise the rare potentially life threatening adverse effect of dapsone therapy, its timely diagnosis and favourable outcome with systemic glucocorticoid therapy.

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