scholarly journals Use of labetalol and glyceryl trinitrate for induced hypotension in spine surgery- A comparative study

2014 ◽  
Vol 22 (2) ◽  
pp. 48-53 ◽  
Author(s):  
Sabina Yeasmeen ◽  
Md Rafayet Ullah Siddique ◽  
Amirul Islam ◽  
AKM Aktaruzzaman ◽  
Debabrata Banik ◽  
...  

Background: Induced hypotension is used to reduce blood loss especially in those operations where even a small amount of blood can obscure the operative field such as spine surgery. Objectives: To compare the effect of labetalol with that of glyceryl trinitrate to reduce intraoperative blood loss by inducing elective hypotension without any tachycardia and to improve quality of surgical field during spine surgery. Method: A total number of thirty patients (ASA grade I & II) were selected randomly into two groups, fifteen in each group. Group-I received glyceryl tinitrate (1000?g) and Group-II received labetalol (5mg) intravenously 3 minutes before induction of anaesthesia. Heart rate, mean arterial pressure was observed in two study groups 15 minutes interval in intra-operative period and quality of surgical field was detected by 4 points VRS (Verbal rating scale) after completion of surgery by asking the surgeon. Results: Heart rate varied significantly in two study groups after induction of anaesthesia except baseline and pre induction (p< 0.05). Labetalol associated with improved quality of surgical field visualization than glyceryltrinitrate (p = 0.034). Conclusion: Our study concluded that labetalol is effective than glyceryltrinitrate to reduce blood loss in spine surgery. DOI: http://dx.doi.org/10.3329/jbsa.v22i2.18141 Journal of BSA, 2009; 22(2): 48-53

1997 ◽  
Vol 87 (Supplement) ◽  
pp. 139A
Author(s):  
M.K. Urban ◽  
J. Beckman ◽  
O. Adjei-Boachie ◽  
B. Urquhart

Author(s):  
Richard Young

Carotid body tumors are a rare type of head and neck tumor that can be safely resected with the help of pre-operative neuro-interventional embolization. This adjunct intervention helps reduce blood loss and to maintain a near bloodless surgical field that allows for good visualization of surrounding neurovascular elements. With the improvements of neuroimaging in the angiography suite and technologies surrounding neuro-interventional procedures, the complications of this procedure have decreased dramatically compared to what was reported in the 1980s-2000s.


2007 ◽  
Vol 105 (5) ◽  
pp. 1404-1409 ◽  
Author(s):  
Vladimir Nekhendzy ◽  
Hendrikus J. M. Lemmens ◽  
Winston C. Vaughan ◽  
Edward J. Hepworth ◽  
Alexander G. Chiu ◽  
...  

2019 ◽  
Vol 4 (2) ◽  
pp. 1-8
Author(s):  
Ahmed A. Sadek ◽  
Mokhtar Mostafa ◽  
Tarek Abdel-Monem

Background and Objectives: The success of functional endoscopic sinus surgery (FESS) depends on the visual clarity of the surgical field, which is understudied. Controlled hypotension has many advantages for FESS including reduction in blood loss and improved quality of the surgical field. This study determined whether the use of β-blockers as a premedication could improve the operative field in FESS. Methods: Sixty patients aged from 18 to 50 years, undergoing septoplasty and FESS were included in this prospective, randomized, double-blind, placebo-controlled study. Patients were randomly assigned to receive either metoprolol (100 mg, group 1) or a placebo (a vitamin tablet, group 2) 60 min before surgery. Results: The average blood loss and surgery duration were not significantly higher in the placebo group. The surgical field was graded using the Fromme-Boezaart scale, and it was significantly clearer (p < 0.001) in metoprolol group. The mean arterial blood pressure was significantly lower in the metoprolol group after 30 min of induction until the end of surgery (p < 0.001). The heart rate was also significantly lower (p < 0.001) in those who received metoprolol from before induction of anesthesia up to the end of surgery. Conclusion: Metoprolol significantly improves visual clarity and hemodynamics during FESS. We would recommend the use of metoprolol in FESS and septoplasty.


2014 ◽  
Author(s):  
Amlan Swain ◽  
Jyotsna Wig ◽  
Nidhi Panda ◽  
Ritesh Lamsal ◽  
K. Mukherjee

2014 ◽  
Vol 8 (4) ◽  
pp. 4-8
Author(s):  
Aksana Kotava ◽  
Vasily Senko ◽  
Ruslan Shishko

Background: The efectiveness of the vegetative regulation action might be controlled by the method of heart rate variability (HRV), which has been very popularly used over the last 10 years worldwide. The analysis of many clinical studies indicates that the severity of the disease might be controlled using the method of HRV.Material and methods: All the experimental and controlled group participants, which consisted of healthy students with none sports experience, underwent the examination according to the 5-minute standard protocol of HRV. In addition, all the examinees performed a bicycle stress test. After the bicycle stress test, some additional tests of HRV were also carried out.Results: It was found that some signifcant diferences, between the group of sportsmen and the group of patients, exist. The parasympathetic activity of LF is maximum in athletes and tends to decrease in patients with cardiovascular pathologies. The decreases of the activity of the vasomotor centre was noticed in both study groups. The sympathetic system activity was the lowest in athletes.Conclusions: At the high depression of the vegetative regulation, any signifcant load (physical or psycho-emotional) indicates cardiovascular instability which remains beyond the capacity of adaptation. The higher the variability, the more stable the CVS is to the external loads. A sharp decrease of the variability, such as the heart vegetative innervations, causes deteriorating quality of the regulatory mechanisms and, as a result, the risk of cardiovascular diseases increases.Keywords: heart rate variability, deterministic and stochastic loads, cardiovascular system


Sign in / Sign up

Export Citation Format

Share Document