scholarly journals Ice-on-Eyes Test in the Diagnosis of Myasthenia Gravis

2012 ◽  
Vol 2 (2) ◽  
pp. 92-93
Author(s):  
Nazmul Haque ◽  
Rukhsana Parvin ◽  
Naser Ahmed ◽  
AKM Rafique Uddin
Keyword(s):  
Case Report ◽  
Cost Effectiveness ◽  
Myasthenia Gravis ◽  
Neuromuscular Transmission ◽  
Muscle Membrane ◽  
College Hospital ◽  
Medical College ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
Tensilon Test

Myasthenia gravis is the most frequent autoimmune neuromuscular transmission disorder  with incidence of 2-20 patients per million. Its pathophysiology is autoimmune, with  acetylcholine receptor auto antibodies damaging the post-synaptic fold at the muscle  membrane. The diagnostic confirmation of myasthenia gravis is often challenging. Ice-oneyes  test can be used to diagnose this disease for its simplicity, safety and cost-effectiveness. Here we report a case of myasthenia gravis in Enam Medical College Hospital, Savar, Dhaka where ice-on-eyes test was done with improvement of ptosis of the patient. Aim of this case  report is to make aware our physicians to apply this simple bed side test instead of common  traditional edrophonium (tensilon test) test for confirmation of the diagnosis of ocular myasthenia gravis. DOI: http://dx.doi.org/10.3329/jemc.v2i2.12845 J Enam Med Col 2012; 2(2): 92-93  

Tobramycine eye drops and ocular myasthenia gravis reactivation: A case report

Therapies ◽  
2020 ◽  
Author(s):  
Claire de Canecaude ◽  
Christophe Gazagne ◽  
Magali Paraire ◽  
Geneviève Durrieu
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Eye Drops ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

Ptosis and Neuromuscular Syndromes

2014 ◽  
pp. 83-119
Author(s):  
Shirley H. Wray
Keyword(s):  
Myasthenia Gravis ◽  
Neuromuscular Transmission ◽  
Clinical Importance ◽  
Progressive External Ophthalmoplegia ◽  
Oculopharyngeal Muscular Dystrophy ◽  
Fisher Syndrome ◽  
Ocular Myasthenia ◽  
Kearns Sayre Syndrome ◽  
Ocular Myasthenia Gravis

emphasizes the clinical importance of a careful patient history detailing the onset of ptosis, its variability, and its progression. A pattern of ocular and generalized muscle weakness is a central diagnostic attribute of impaired nerve conduction due to disease of the neuromuscular junction. Generalized myasthenia gravis, ocular myasthenia gravis, MuSK-myasthenia gravis, and a case of the Lambert-Eaton syndrome illustrate the spectrum of disorders of neuromuscular transmission. The syndrome known as chronic progressive external ophthalmoplegia is by far the most common of the mitochondrial myopathies progressing to the multisystem failure that is characteristic of the Kearns-Sayre syndrome. A case of Kearns-Sayre syndrome followed for 34 years is a unique case study. Two inherited forms of myopathy, oculopharyngeal muscular dystrophy and myotonic dystrophy, are included, together with a patient with the Guillain-Barré syndrome variant, Fisher syndrome. These disorders should always be considered in the differential diagnosis of bilateral progressive ptosis.

Unilateral ocular myasthenia gravis in an acute medical take: is a Tensilon test useful?

2006 ◽  
Vol 67 (4) ◽  
pp. 210-210
Author(s):  
D McCarthy ◽  
C Patel ◽  
JAO Ahlquist ◽  
JW Stephens
Keyword(s):  
Myasthenia Gravis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
Tensilon Test

scholarly journals Miastenia Gravis Okular Juvenil: Laporan Kasus

2021 ◽  
Vol 1 (1) ◽  
pp. 39-52
Author(s):  
Fikta Zakia Nurfaizah ◽  
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Case Reports ◽  
Test Results ◽  
Upper Eyelid ◽  
Ocular Myasthenia ◽  
Confirmation Test ◽  
Ocular Myasthenia Gravis ◽  
Relevant Case ◽  
The Subject

Abstract Purpose: This study aimed to summarize the general history, physical exam findings, confirmation test, and treatment of a patient with juvenile ocular myasthenia gravis. Research Methodology: This article is a pediatric RSUD Abdoel Moeloek Lampung case report in April 2021. The subject of the case is a 3-year-old girl who is hospitalized in the hospital ward with juvenile ocular myasthenia gravis. Result: A 3-year-old girl, an inpatient in the Pediatric Ward, RSUD Abdoel Moeloek Lampung, with complaints of decreased left upper eyelid since three months ago. On physical examination, there was ptosis of the left superior palpebra. Prostigmine test was performed on day 2 of treatment in patients with positive test results. The patient was clinically diagnosed with “Juvenile Ocular Myasthenia Gravis.” Management of the patient during treatment was the injection of methylprednisolone 10 mg/12 hours and neostigmine orally 2.5 mg/8 hours. Limitations: This case report is limited to juvenile ocular myasthenia gravis cases with a scarce number of cases and rare cases in children. Contribution: This case report can be helpful in medical education or used as a reference in making relevant case reports and can be applied in the hospital area when there are cases of juvenile ocular myasthenia gravis.

scholarly journals Seeking spark- ocular myasthenia gravis in a juvenile – an Indian case report

2020 ◽  
Vol 5 (7) ◽  
pp. 190-193
Author(s):  
Dr. Usha BR. ◽  
◽  
Dr. Nandhini K ◽  
Dr. Chaitra MC ◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Neuromuscular Junction ◽  
Myasthenia Gravis ◽  
Autoimmune Disorder ◽  
Bilateral Ptosis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
History Of ◽  
High Index Of Suspicion

Myasthenia gravis (MG) is a rare autoimmune disorder affecting neuromuscular junction by muscleweakness. Myasthenia gravis can be generalized or localized as ocular myasthenia gravis. Casepresentation: We report an 8-year-old boy who presented with 10 days history of drooping of botheyelids and 8 days history of diplopia. Examination revealed bilateral ptosis. A diagnosis of JuvenileOcular Myasthenia gravis was made when symptoms improved with intramuscular Edrophoniumadministration. He was commenced on oral Neostigmine at a dose of 2mg/Kg/ day,4 hourly individed doses and is on regular follow up and had a good response. Conclusion: Ocular Myastheniagravis (OMG) is a rare disease in itself. A high index of suspicion is required in a juvenile as it iseven rarer.

scholarly journals A clinical approach to ocular myasthenia gravis

2015 ◽  
Vol 4 (3) ◽  
pp. 5-8
Author(s):  
S Sitaula ◽  
A K Sharma ◽  
M Thapa ◽  
B P Gajurel ◽  
R P Sah
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptors ◽  
Care Center ◽  
Immunosuppressive Drugs ◽  
Clinical Approach ◽  
Double Vision ◽  
Medical College ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
Diagnostic Difficulties

Myasthenia gravis is a common disorder of the neuromuscular junction characterized clinically by muscle weakness and fatigability. Ocular myasthenia is often misdiagnosed in the initial stages due to the fluctuating nature of ptosis and diplopia. Here, we describe the clinical characteristics of ocular myasthenia gravis along with the diagnostic difficulties in a tertiary eye care center in Nepal. We retrospectively reviewed the charts of the patients diagnosed as ocular myasthenia gravis in Neuro-ophthalmology clinic, BPKLCOS, from 2010 to 2013. The diagnosis of ocular myasthenia was based on the association of typical history and signs together with at least one of these features: unequivocal improvement of ocular signs after injection of neostigmine, positive response to electrophysiological tests and detection of serum antibodies to acetylcholine receptors. There were 24 cases of diagnosed ocular myasthenia gravis during the 3 years. Among them 11 cases (45.8%) were males and 13 cases (54.1%) were females. The mean age was 32.04±19.56 years with the age range from 9 years to68 years. The most common symptoms among patients were drooping of the lids (45.8%, n=11), followed by both double vision and drooping of the lids (37.5%, n=9) and only intermittent double vision in16.6% (n=4). In two patients (9.09%) CT-scan findings were suggestive of thymoma. The symptoms were resolved with anticholinesterases alone in 66.6% (n=16) and anticholinesterases were supplemented with immunosuppressive drugs in 33.3% (n=8) patients. Ocular myasthenia is often misdiagnosed in the initial stages due to its fluctuating nature. With a high index of clinical suspicion simple clinical tests accompanied by pharmacological tests can be useful in diagnosing the condition.DOI: http://dx.doi.org/10.3126/jcmc.v4i3.11931Journal of Chitwan Medical College 2014; 4(3): 5-8

scholarly journals New onset of ocular myasthenia gravis in a patient with COVID-19: a novel case report and literature review

2020 ◽  
Author(s):  
Shitiz Sriwastava ◽  
Medha Tandon ◽  
Saurabh Kataria ◽  
Maha Daimee ◽  
Shumaila Sultan
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Myasthenia Gravis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
New Onset
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