scholarly journals Significance of Biochemical Difference between Childhood Nephrotic Syndrome with UTI and without UTI

KYAMC Journal ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 22-25
Author(s):  
Kazi ASM Shamim Parvez ◽  
Md Khalilur Rahman ◽  
Md Razikul Islam ◽  
Md Sanaul Haque
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Data Collection ◽  
Tract Infection ◽  
Serum Albumin ◽  
Serum Cholesterol ◽  
Childhood Nephrotic Syndrome ◽  
Nephritic Syndrome ◽  
Biochemical Difference

Background: Nephrotic syndrome is one of most common renal disease in childhood and infection is one of the most important complication in this disease. Infection increase the mortality and morbidity of this type of patients. Most common infection is UTI. So through this study we can able to determine biochemical difference between childhood nephrotic syndrome with Urinary Tract Infection (UTI) and with out UTI patients and its clinical significance. Objective: To determine the biochemical different in childhood nephrotic syndrome patients and its relation with urinary tract infection. Materials and Methods: It is prospective study done in pediatric department in Rajshahi Medical College Hospital, 60 patient of both sex age between 1-12 years, diagnosed as idiopathic nephrotic syndrome with and without UTI were included in this study. Data collection ware done by history taking, clinical examination, laboratory investigations and followed up. Patients were followed up till cure of UTI and remission of proteinuria. After data collection statistical analysis were done by computerized software. Results: In our study we found there were biochemical difference between childhood nephrotic syndrome with UTI and without UTI patients. In patients of nephrotic syndrome with UTI serum albumin decrease significantly and serum cholesterol increase significantly than nephritic syndrome without UTI patients. Conclusion: Child with nephrotic with UTI patients had lower serum albumin and higher serum cholesterol than nephrotic syndrome without UTI patients and it effect the morbidity mortality of this patients. KYAMC Journal.2021;12(1): 22-25

scholarly journals Urinary Tract Infection in Nephrotic Syndrome in Pediatric Age Group: A Hospital Based Cross-sectional Study.

2020 ◽  
Author(s):  
Subhendu Samanta
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection ◽  
Serum Cholesterol ◽  
Pediatric Population ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
Renal Disorder ◽  
Sensitivity Pattern

Abstract Background::Nephrotic syndrome, characterized by the presence of heavy proteinuria, hypoalbuminemia, edema and hyperlipidemia, is a common renal disorder in pediatric population. Aim of this study were to find out the prevalence of UTI in nephrotic syndrome, bacterial etiologies and antibiotic sensitivity pattern.Methods:After matching the criteria, 82 cases, were taken for this prospective, single center, observational study.The diagnosis was confirmed by bacterial culture.This is an institution based cross-sectional descriptive observational study. All newly diagnosed and relapse cases of nephrotic syndrome based on inclusion exclusion criteria was included in this study. Respondent was either of the parents or caregiver of the study subjects. Analysis of all data was done by appropriate statistical software(SPSS-23).Results:Among 82 participants evaluated with nephrotic syndrome 29.3% participants had Urinary Tract Infection ,majority66.7%were asymptomatic and 33.3% were symptomatic. Significant microscopic hematuria were found in 20.7% study subjects and significant pyuria were found in 58.54% study subjects. Majority of UTI caused by E.coli 33.3% followed by Klebsiella 25%,Proteus16.7%,Staphylococcus aureus 12.5% ,Citrobacter,Acenetobacter and mixed growth werefound in 4.2%each.Mean serum cholesterol of group with UTI was 422.13±34.65 and group without Urinary Tract Infection was307.43±26.13.The variation amongst the two groups were found to be significant (P=0.0001).Conclusions:The children with nephrotic syndrome are frequently predisposed to Urinary Tract Infection and in most cases it is asymptomatic, often undiagnosed. Higher serum cholesterol level may predispose the nephrotic child for Urinary Tract Infection.

scholarly journals Urinary Tract Infection in Nephrotic Syndrome: A Hospital Based Cross-Sectional Study

2017 ◽  
Vol 15 (2) ◽  
pp. 41-44 ◽  
Author(s):  
Tanuka Barua ◽  
Razia Sultana ◽  
Fazal Karim Babul ◽  
Shahed Iqbal ◽  
Jhulan Das Sharma ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection ◽  
Serum Cholesterol ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio

Background: Urinary Tract Infection (UTI) is a common infection in nephrotic syndrome and have a propensity for long term renal damage. It may be an important cause of poor steroid response. The objective is to study the frequency and etiological organisms of urinary tract infection in idiopathic nephrotic syndrome children.Methods: This Comparative cross-sectional study was conducted in the Pediatric ward of Chittagong Medical College Hospital, Chittagong from 01.01.2009 to 31.12.2009. 52 nephrotic syndrome children diagnosed by serum albumin, serum cholesterol and 24 hours total urinary protein or protein creatinin index were included. After elaborate clinical evaluation, urine for R/M/E and C/S was done in all patients. Data regarding pyuria, hematuria, etiological organisms were analyzed by statistical method.Results: UTI was found in 30.8% nephrotic children and in majority cases (68.8%) they were asymptomatic. Male female ratio among UTI patients was 1:1. Mean serum cholesterol in nephrotic syndrome with UTI was higher than that of children without UTI (418.94 mg/dl vs 352.03 mg/dl, p value < 0.05).Pyuria had poor association with definite UTI (p value > 0.05). E-coli was the commonest organism isolated in urine culture followed by klebsiella.Conclusion: UTI is one of the most common infections in nephrotic syndrome and may be asymptomatic. It should be screened in every nephrotic child routinely.Chatt Maa Shi Hosp Med Coll J; Vol.15 (2); Jul 2016; Page 41-44

scholarly journals Urinary tract infection in nephrotic syndrome in pediatric age group: a hospital based cross-sectional study

2020 ◽  
Vol 7 (8) ◽  
pp. 1787
Author(s):  
Subinay Mandal ◽  
Subhendu Samanta ◽  
Sabyasachi Bakshi ◽  
Devidutta Dash
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection ◽  
Observational Study ◽  
Serum Cholesterol ◽  
Pediatric Population ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
Renal Disorder

Background: Nephrotic syndrome, characterized by the presence of heavy proteinuria, hypoalbuminemia, edema and hyperlipidemia, is a common renal disorder in pediatric population. Aim of this study were to find out the prevalence of Urinary Tract Infection (UTI) in nephrotic syndrome, bacterial etiologies and antibiotic sensitivity pattern.Methods: After matching the criteria, 82 cases, were taken for this prospective, single center, observational study. The diagnosis was confirmed by bacterial culture. This is an institution based cross-sectional descriptive observational study. All newly diagnosed and relapse cases of nephrotic syndrome based on inclusion exclusion criteria was included in this study. Respondent was either of the parents or caregiver of the study subjects. Analysis of all data was done by appropriate statistical software (SPSS-23).Results: Among 82 participants evaluated with nephrotic syndrome 29.3% participants had UTI, majority 66.7% were asymptomatic and 33.3% were symptomatic. Significant microscopic hematuria were found in 20.7% study subjects and significant pyuria were found in 58.54% study subjects. Majority of UTI caused by E.coli 33.3% followed by Klebsiella 25%, Proteus 16.7%, Staphylococcus aureus 12.5%, Citrobacter, Acinetobacter and mixed growth were found in 4.2% each. Mean serum cholesterol of group with UTI was 422.13±34.65 and group without UTI was 307.43±26.13. The variation amongst the two groups were found to be significant (p=0.0001).Conclusions: The children with nephrotic syndrome are frequently predisposed to UTI and in most cases it is asymptomatic, often undiagnosed. Higher serum cholesterol level may predispose the nephrotic child for UTI.

Urinary tract infection in nephrotic syndrome

1996 ◽  
Vol 15 (3) ◽  
pp. 237-240 ◽  
Author(s):  
S. GULATI ◽  
V. KHER ◽  
P. ARORA ◽  
S. GUPTA ◽  
S. KALE
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection

Urinary Tract Infection in Children with Idiopathic Nephrotic Syndrome

2020 ◽  
Vol 106 (6) ◽  
Author(s):  
Faris M Alhares ◽  
Aymen A Albakaa ◽  
Alaa Jumaah Nasrawi ◽  
Naim Salim
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection ◽  
Idiopathic Nephrotic Syndrome

scholarly journals Causative Agents and Susceptibility of Antimicrobials among Suspected Females with Urinary Tract Infection in Tertiary Care Hospitals of Western Nepal

2013 ◽  
Vol 3 (2) ◽  
pp. 16-19 ◽  
Author(s):  
P Thapa ◽  
K Parajuli ◽  
A Poudel ◽  
A Thapa ◽  
B Manandhar ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Data Collection ◽  
Tract Infection ◽  
Tertiary Care ◽  
Bacterial Pathogen ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Causative Agents ◽  
Collection Form

Urinary Tract Infection (UTI) is a common and serious health problem affecting many people each year around the World especially females. Therapy of UTI relies on the predictability of the agents causing UTI and knowledge of their antimicro­bial susceptibility patterns. A retrospective cross-sectional study was conducted in two major hospitals of Western Nepal. Tools for data collection were a data collection form. Total 400 patient’s file with suspected UTI were reviewed, out of which 173 (43.3 %) of the suspected samples showed presence of potential pathogens causing UTI. UTI was mostly prevalent in females of age group 21-30. Escherichia coli (E. coli) was the predominant (65.1%) bacterial pathogen. Amikacin was found to be most sensitive antimicrobial followed by Nitrofurantoin and Gentamcin. Ampicillin showed the higher percentage of resistant, compared to other antimicrobials. As drug resistance among bacterial pathogens is an evolving process, regular surveillance and monitoring is necessary to provide effective treatment of UTIs. DOI: http://dx.doi.org/10.3126/jcmc.v3i2.8436 Journal of Chitwan Medical College Vol.3(2) 2013 16-19

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