scholarly journals Giant Phyllodes Tumor: A Case Report and Review of the Literature?

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Bueno Carolina ◽  
Steim Jéssica ◽  
Roque Fernanda ◽  
Sato Alan ◽  
Chambô Danielle ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Perineural Invasion ◽  
Standard Treatment ◽  
Immunohistochemical Analysis ◽  
Phyllodes Tumor ◽  
Left Breast ◽  
Definitive Diagnosis ◽  
High Grade ◽  
Review Of The Literature ◽  
Malignant Phyllodes Tumor

Phyllodes tumor is a rare, fast-growing, fibroepithelial neoplasm of the breast that can be classified as benign, borderline or malignant. The case reported here refers to a 25-year old patient with a lump on her left breast that grew rapidly in the postpartum period, reaching 21 cm in size. Core biopsy and immunohistochemical analysis indicated a diagnosis of high-grade phyllodes tumor. The patient underwent mastectomy of the left breast followed by breast reconstruction. Histopathology confirmed a malignant phyllodes tumor with chondrosarcomata’s and fibrosarcomatous differentiation and no angiolymphatic or perineural invasion. Phyllodes tumors are generally benign and differential diagnosis is usually made with fibroadenomas; however, clinical differentiation can be difficult in some cases. The definitive diagnosis is achieved by histopathology, which is able to differentiate benign from malignant forms of the disease. Standard treatment consists of local excision, with mastectomy being necessary in cases of borderline, large, malignant or recurrent tumors.

scholarly journals Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Canan Kelten ◽  
Ceren Boyaci ◽  
Cem Leblebici ◽  
Kemal Behzatoglu ◽  
Didem C. Trabulus ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Cyst ◽  
Clinical Breast Examination ◽  
Phyllodes Tumor ◽  
Breast Cancer Diagnosis ◽  
Left Breast ◽  
Malignant Phyllodes Tumor ◽  
Her Family ◽  
Simple Mastectomy ◽  
Clinical Breast

Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

scholarly journals Granulocyte-colony stimulating factor-producing malignant phyllodes tumor of the breast: a rare case

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kimihisa Mizoguchi ◽  
Kazuhisa Kaneshiro ◽  
Makoto Kubo ◽  
Yoshihiko Sadakari ◽  
Yoshizo Kimura ◽  
...  
Keyword(s):  
Rare Case ◽  
Phyllodes Tumor ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Malignant Phyllodes Tumor ◽  
Csf Levels ◽  
Wbc Count ◽  
Stimulating Factor

Abstract Background Granulocyte-colony stimulating factor (G-CSF)-producing tumors can cause leukocytosis despite an absence of infection. G-CSF-producing tumors have been reported in various organs such as the lung, esophagus, and stomach but rarely in the breast. We report a case of G-CSF-producing malignant phyllodes tumor of the breast. Case presentation An 84-year-old woman visited our hospital complaining of a lump in her left breast without fever and pain. Laboratory tests revealed elevated white blood cell (WBC) count and G-CSF levels. A malignant tumor of the breast was diagnosed by core needle biopsy. We performed a total mastectomy and sentinel lymph node biopsy. The tumor was identified as a G-CSF-producing malignant phyllodes tumor. Within 7 days after surgery, the patient’s WBC count and G-CSF level had decreased to normal levels. She is alive without recurrence 13 months after surgery. Conclusions We encountered a rare case of G-CSF-producing malignant phyllodes tumor of the breast. PET–CT revealed diffuse accumulation of FDG in the bone. Phyllodes tumors need to be differentiated from bone metastasis, lymphoma, and leukemia. We must be careful to not mistake this type of tumor for bone marrow metastasis.

scholarly journals Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Gabriel S. Makar ◽  
Michael Makar ◽  
Joanna Ghobrial ◽  
Kathryn Bush ◽  
Ryan Allen Gruner ◽  
...  
Keyword(s):  
Breast Neoplasms ◽  
Rare Case ◽  
Phyllodes Tumor ◽  
Adolescent Females ◽  
Small Subset ◽  
Review Of The Literature ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors ◽  
Rare Case Report

Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females.

Synovial osteochondromatosis. A brief review

1992 ◽  
Vol 82 (8) ◽  
pp. 427-431 ◽  
Author(s):  
R Valmassy ◽  
H Ferguson
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Clinical Finding ◽  
Definitive Diagnosis ◽  
Loss Of Function ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Synovial Osteochondromatosis ◽  
Benign Process

An unusual clinical finding is presented with a brief review of the literature. Synovial osteochondromatosis is typically a benign process involving metaplasia of the synovial intima and the formation of cartilaginous nodules that may eventually become ossified. Synovial osteochondromatosis should always be considered as a differential diagnosis whenever a patient presents with pain, swelling, and loss of function at or around a joint. Chondrosarcoma has been misdiagnosed, leading to radical and unnecessary amputation, because synovial osteochondromatosis has not been considered. Alternatively, synovial osteochondromatosis may degenerate to or be associated with a malignant process. When radiographs or more sophisticated investigative procedures, such as magnetic resonance imaging, fail to provide a conclusive answer, histologic findings provide the definitive diagnosis.

scholarly journals Leiomyosarcoma of the epididymis: 2 cases and review of the literature

2013 ◽  
Vol 5 (6) ◽  
pp. 121
Author(s):  
Victor T.H. Yuen ◽  
Shane D. Kirby ◽  
Young Chi Woo
Keyword(s):  
Blood Flow ◽  
Differential Diagnosis ◽  
Spermatic Cord ◽  
Community Hospital ◽  
Primary Treatment ◽  
High Ligation ◽  
High Grade ◽  
Review Of The Literature ◽  
Important Differential Diagnosis

Paratesticular leiomyosarcomas are rare. We report two cases ofleiomyosarcoma of the epididymis diagnosed and treated in aregional community hospital in Canada in 2009 and 2010. Bothpatients were males of ages 58 and 75, respectively. They presentedwith painless masses which, on ultrasonography, appeared to besolid masses demonstrating blood flow. Each patient underwenttrans-scrotal resection of the affected epididymis. Pathologicalexamination of trans-scrotal epididymectomy specimens confirmedthe diagnosis of high-grade leiomyosarcoma. Leiomyosarcoma isan important differential diagnosis for paratesticular masses in theelderly male; the primary treatment is radical inguinal orchiectomywith high ligation of the spermatic cord.

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