scholarly journals Intravenous Thrombolysis in Acute Branch Retinal Artery Occlusion Based on the Stroke Green Channel: A Case Report

2021 ◽  
Vol 5 (3) ◽  
pp. 1-4
Author(s):  
LiDan Xie ◽  
Hong Zhang ◽  
Xiaoqin Ye ◽  
Qilong Xie
Keyword(s):  
Time Window ◽  
Intravenous Thrombolysis ◽  
Blood Perfusion ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Acute Onset ◽  
Eye Disease ◽  
Green Channel ◽  
Retinal Artery ◽  
Artery Obstruction

Retinal artery occlusion is an acute-onset eye disease that seriously impairs vision, and is a critical condition in ophthalmology. The effect of traditional ophthalmology treatment methods are not ideal. It is difficult to recanalize blocked blood vessels early, but thrombolysis can be given within an effective time window to dissolve the thrombus, improve retinal blood perfusion and restore the function of the retinal inner layer cells. Under the protection of the green channel for stroke, we performed intravenous thrombolysis for patients with branch retinal artery obstruction, and achieved satisfactory results, and the patients were cured.

Management of acute central retinal artery occlusion: Intravenous thrombolysis is feasible and safe

2017 ◽  
Vol 12 (7) ◽  
pp. 720-723 ◽  
Author(s):  
Cécile Préterre ◽  
Gaelle Godeneche ◽  
Xavier Vandamme ◽  
Thomas Ronzière ◽  
Matthias Lamy ◽  
...  
Keyword(s):  
Central Retinal Artery Occlusion ◽  
Intravenous Thrombolysis ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Retinal Artery

Is Intravenous Thrombolysis Safe and Effective in Central Retinal Artery Occlusion? A Critically Appraised Topic

2017 ◽  
Vol 22 (4) ◽  
pp. 153-156 ◽  
Author(s):  
Oana M. Dumitrascu ◽  
Joanne F. Shen ◽  
Madhavi Kurli ◽  
Maria I. Aguilar ◽  
Lisa A. Marks ◽  
...  
Keyword(s):  
Central Retinal Artery Occlusion ◽  
Intravenous Thrombolysis ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Retinal Artery

scholarly journals Determination of Ischemia Onset Based on Automatically Generated Spectralis SD-OCT Values in Acute Central Retinal Artery Occlusion

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Casagrande ◽  
Robert Kromer ◽  
Daniel A. Wenzel ◽  
Sven Poli ◽  
Martin S. Spitzer ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Time Window ◽  
Retinal Thickness ◽  
Central Retinal Artery Occlusion ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Retinal Layer ◽  
Retinal Artery ◽  
Sd Oct

Acute central retinal artery occlusion (CRAO) induces a time-dependent increase in retinal thickness. By manually measuring the relative retinal thickness increase (RRTI) in comparison to the contralateral eye based on optical coherence tomography (OCT), ischemia onset within the past 4.5 hours could be determined with 100% sensitivity and 94.3% specificity. To enable examiner-independent and quicker diagnostics, we analyzed the RRTI using the automatic retinal thickness measurement. In this retrospective study, 28 eyes were evaluated with an acute CRAO (<46 hours). All patients received a Spectralis SD-OCT image of both eyes. The RRTI was calculated for the ETDRS sectors using the Segmentation Module for Single Retinal Layer Analysis. Receiver operating characteristic (ROC) analysis was performed to determine patients ≤4.5 hours by RRTI. In all sectors, time to OCT (TTO) and RRTI correlated positively. The optimal cutoff point to detect CRAOs ≤4.5 hours was between 18.7% nasally and 22.9% RRTI temporally. Sensitivity and specificity varied between the sectors with 90–95% sensitivity and 89–100% specificity. In conclusion, the automatic measurement of RRTI also allows the differentiation of CRAOs within a possible therapeutic time window ≤4.5 hours and CRAOs ≥4.5 hours with a high sensitivity and specificity. Additionally, it offers quicker, easier, and a user-independent assessment of ischemia onset, helping to set a base for establishing automatic indices generated by the OCT machines.

scholarly journals Bilateral central retinal artery occlusion from catastrophic antiphospholipid syndrome

2018 ◽  
pp. bcr-2018-226463 ◽  
Author(s):  
Udit Joshi ◽  
Sana Afroz ◽  
Sagar Ranka ◽  
Benjamin Mba
Keyword(s):  
Antiphospholipid Syndrome ◽  
Central Retinal Artery Occlusion ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Acute Onset ◽  
Central Retinal Artery ◽  
Left Index Finger ◽  
High Dose ◽  
Catastrophic Antiphospholipid Syndrome ◽  
Retinal Artery

A 23-year-old woman with history of systemic lupus erythematous presented with dizziness and headache and was admitted for the stroke workup. During her stay, she had sudden painless loss of vision in her right eye consistent with central retinal artery occlusion (CRAO). Ocular massage and paracentesis were attempted without success to resume the flow. She was started on oral high-dose steroids (1 mg/kg) for lupus flare and therapeutic anticoagulation for antiphospholipid syndrome (positive for anticardiolipin and beta-2 microglobulin antibodies). On day 4, she started having painful bluish discoloration of her left index finger and right fifth toe, and on day 5 she had acute onset of left blurry vision with findings consistent with CRAO. She fulfilled the criteria of catastrophic antiphospholipid syndrome and was started on intravenous pulse steroids, plasmapheresis and higher international normalised ratio goal of 3–3.5 with improvement in her left eye vision from 20/200 to 20/20 on near card test by the end of treatment.

scholarly journals Akut arteria centralis retinae elzáródás.

2021 ◽  
Vol 162 (47) ◽  
pp. 1871-1875
Keyword(s):  
Central Retinal Artery Occlusion ◽  
Intravenous Thrombolysis ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Central Retinal Artery ◽  
Vascular Events ◽  
Irreversible Damage ◽  
Cerebrovascular Events ◽  
Retinal Artery ◽  
Definition Of

Összefoglaló. Az agy és a szem vascularis katasztrófái számos esetben egymáshoz társuló vagy egymást előre jelző kórképek. Az arteria centralis retinae occlusio az ér rekanalizációjának hiányában a retina szöveteinek irreverzibilis károsodását okozza. Sem a nemzetközi, sem a hazai stroke-irányelvek nem foglalkoznak az ocularis stroke problémakörével, annak ellenére, hogy az arteria centralis retinae occlusio okozta retinalis ischaemia minden tekintetben megfelel az akut ischaemiás stroke definíciójának. Az eddig rendelkezésre álló irodalmi adatok alapján arteria centralis retinae occlusio esetén az intravénás thrombolysis 4,5 órán belül alkalmazva növeli a szignifikáns mértékű visusjavulás esélyét. Az országban jelenleg 4 centrum (Pécsi Tudományegyetem, Szegedi Tudományegyetem, Debreceni Egyetem, Semmelweis Egyetem) tervezi az ocularis stroke kezelésében a thrombolysis bevezetését. A maradandó látásromlás és a szekunder cerebrovascularis események megelőzése érdekében elengedhetetlen az alapellátásban és a társszakmákban dolgozó kollégákkal való szoros együttműködés. Orv Hetil. 2021; 162(47): 1871–1875. Summary. Vascular events of the brain and the eye may occur concomitantly or sequentially. In the absence of recanalization, central retinal artery occlusion causes irreversible damage to the retinal tissues. Even though retinal ischemia secondary to central retinal artery occlusion meets the definition of acute ischemic stroke, neither the international nor the Hungarian stroke guidelines mention ocular stroke. Based on the available literature, intravenous thrombolysis of the central retinal artery within 4.5 hours of occlusion can increase the odds of significant vision improvement. Currently 4 centers (University of Pécs, Debrecen, Szeged, and Semmelweis University) are planning to introduce thrombolysis in the treatment of ocular stroke. To prevent permanent visual loss and secondary cerebrovascular events, timely intervention requires the collaboration between general practitioners and other specialties. Orv Hetil. 2021; 162(47): 1871–1875.

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