scholarly journals The efficacy of GABAergic precursor cells transplantation in alleviating neuropathic pain in animal models: a systematic review and meta-analysis

2022 ◽  
Vol 35 (1) ◽  
pp. 43-58
Author(s):  
Shaghayegh Askarian-Amiri ◽  
Solmaz Nasseri Maleki ◽  
Seyedeh Niloufar Rafiei Alavi ◽  
Arian Madani Neishaboori ◽  
Amirmohammad Toloui ◽  
...  
Keyword(s):  
Systematic Review ◽  
Neuropathic Pain ◽  
Animal Models ◽  
Meta Analysis ◽  
Precursor Cells

Neuropathic pain after spinal cord injury and physical exercise in animal models: A systematic review and meta-analysis

2020 ◽  
Vol 108 ◽  
pp. 781-795
Author(s):  
Juliete Palandi ◽  
Franciane Bobinski ◽  
Gabriela Martins de Oliveira ◽  
Jocemar Ilha
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Animal Models ◽  
Physical Exercise ◽  
Meta Analysis ◽  
Cord Injury

Oral administration of mangiferin ameliorates diabetes in animal models: a meta-analysis and systematic review

2020 ◽  
Author(s):  
You Wu ◽  
Wei Liu ◽  
Tao Yang ◽  
Mei Li ◽  
Lingling Qin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Oral Administration ◽  
Meta Analysis

Effects of sleep deprivation on maternal behaviour in animal models: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Gabriel N. Pires ◽  
Thainá B. Oliveira ◽  
Victoria F. F. Mello ◽  
Andréia G. Bezerra ◽  
Cathalijn H. C. Leenaars ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Sleep Deprivation ◽  
Meta Analysis ◽  
Maternal Behaviour

scholarly journals Efficacy of Deferoxamine in Animal Models of Intracerebral Hemorrhage: A Systematic Review and Stratified Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0127256 ◽  
Author(s):  
Han-Jin Cui ◽  
Hao-yu He ◽  
A-Li Yang ◽  
Hua-Jun Zhou ◽  
Cong Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Intracerebral Hemorrhage ◽  
Meta Analysis

Benzodiazepines and antipsychotic medications for treatment of acute cocaine toxicity in animal models – A systematic review and meta-analysis

2011 ◽  
Vol 30 (11) ◽  
pp. 1849-1854 ◽  
Author(s):  
Kennon Heard ◽  
Nathan R Cleveland ◽  
Shay Krier
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Antipsychotic Medication ◽  
English Language ◽  
Absolute Risk ◽  
Meta Analysis ◽  
Absolute Risk Reduction ◽  
Antipsychotic Medications ◽  
Risk Of Death ◽  
Cocaine Toxicity

There are no controlled human studies to determine the efficacy of benzodiazepines or antipsychotic medications for prevention or treatment of acute cocaine toxicity. The only available controlled data are from animal models and these studies have reported inconsistent benefits. The objective of this study was to quantify the reported efficacy of benzodiazepines and antipsychotic medication for the prevention of mortality due to cocaine poisoning. We conducted a systematic review to identify English language articles describing experiments that compared a benzodiazepine or antipsychotic medication to placebo for the prevention of acute cocaine toxicity in an animal model. We then used these articles in a meta-analysis with a random-effects model to quantify the absolute risk reduction observed in these experiments. We found 10 articles evaluating antipsychotic medications and 15 articles evaluating benzodiazepines. Antipsychotic medications reduced the risk of death by 27% (95% CI, 15.2%–38.7%) compared to placebo and benzodiazepines reduced the risk of death by 52% (42.8%–60.7%) compared to placebo. Both treatments showed evidence of a dose-response effect, and no experiment found a statistically significant increase in risk of death. We conclude that both benzodiazepines and antipsychotic medications are effective for the prevention of lethality from cocaine toxicity in animal models.

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