scholarly journals Renal Syndromic Hearing Loss is Common in Childhood-onset Chronic Kidney Disease

2020 ◽  
Vol 35 (44) ◽  
Author(s):  
Ji Hyun Kim ◽  
Dong-Han Lee ◽  
Bongjin Lee ◽  
Seon Hee Lim ◽  
Yo Han Ahn ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease ◽  
Childhood Onset ◽  
Syndromic Hearing Loss

scholarly journals Cochlear function in patients with chronic kidney disease

2013 ◽  
Vol 60 (1) ◽  
Author(s):  
Samantha Marlanie Govender ◽  
Cyril Devdas Govender ◽  
Glenda Matthews
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Drug Intake ◽  
Cochlear Function ◽  
Distortion Product ◽  
Cochlear Dysfunction

Objective: To evaluate cochlear functioning in patients (18 - 45 years old) with varying stages of chronic kidney disease (CKD). Using purposive sampling, 50 participants, 10 in each of the 5 stages of CKD, were selected and underwent pure tone audiometric testing and distortion product otoacoustic emissions (DPOAEs).Results: Significant differences (p<0.05) were found between pure tone audiometry and DPOAEs in detecting early cochlear dysfunction in the high-frequency range in stages 3 (6 000/5 000 Hz; p=0.00), 4 (6 000/5 000 Hz; p<0.03) and 5 (4 000/3 333 Hz; p<0.01, 8 000/6 667 Hz:p<0.05) with DPOAEs being more sensitive in identifying early cochlear dysfunction. Patients in stages 1 and 2 presented with normal puretone thresholds and DPOAEs, suggesting that cochlear functioning in these patients was normal. Early cochlear dysfunction, thereby indicating a subclinical hearing loss, was identified in stages 3, 4 and 5 by DPOAE testing. In addition, blood test results, drug intake and concomitant conditions were recorded and analysed which suggested a relationship between reduced cochlear functioning and increased electrolyte levels, treatment regimens and concomitant conditions.Conclusion: Participants in the later stages of CKD presented with early cochlear dysfunction, presenting with subclinical hearing loss. It was postulated that this subclinical hearing loss resulted from a combination of electrolytic, urea and creatinine imbalances, together with concomitant medical conditions and ototoxic drug intake. It was concluded that audiological monitoring be included in the management of patients with CKD and that DPOAEs be introduced as part of the test battery to monitor cochlear function in patients with varying degrees of CKD.

scholarly journals Chronic kidney disease and the risk of incident hearing loss

2020 ◽  
Vol 130 (4) ◽  
Author(s):  
Shruti Gupta ◽  
Sharon G. Curhan ◽  
Karen J. Cruickshanks ◽  
Barbara E.K. Klein ◽  
Ronald Klein ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease

scholarly journals Correlation of hearing loss with various biochemical and disease parameters in patients with chronic kidney disease

2017 ◽  
Vol 5 (1) ◽  
pp. 8-11
Author(s):  
Dipendra Gautam ◽  
D. Paudel ◽  
S. Thapa ◽  
S.K. Sharma
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease ◽  
Disease Stage ◽  
P Value ◽  
Sodium Potassium ◽  
Co Morbidity ◽  
Sensory Neural ◽  
Sensory Neural Hearing Loss ◽  
Ototoxic Drug

Objectives: To correlate the hearing loss with duration of the disease, stage of the disease, ototoxic drugs use, co-morbidity and biochemical parameters in patients with chronic kidney disease (CKD).Material and Methods: This prospective study of 50 CKD patients was conducted in the department of ototolaryngology head and neck surgery and department of internal medicine, B. P. Koirala Institute of Health Sciences, Dharan, between December 2008 to November 2009. The blood investigation report of the patients were noted. Otological examination was carried out including tunning fork test and pure tone audiometry. Middle ear pathology and conductive hearing loss were excluded. Data was collected and analyzed.Results : Sensory neural hearing loss was higher in patients with; end stage renal disease (stage-5), co-morbidity, haemoglobin level less than 8.5, duration of CKD greater than 2 years, and ototoxic drug administration, but not statistically significant (P-value >0.05). Hearing loss in patients with CKD was not influenced by fasting blood sugar, serum urea, creatinine, sodium, potassium, calcium and serum phosphorus. (P-value >0.05)Conclusion: The hearing loss in patients with chronic kidney disease was not significantly related with stage of CKD, co-morbidity, ototoxic drug use, fasting blood sugar, serum urea, creatinine, sodium, potassium, calcium and serum phosphorus (P-value >0.05). The sensory neural hearing loss in these patients may be due to the advanced age and possible accelerated presbyacusis by the disease.  

scholarly journals Hearing handicap in patients with chronic kidney disease: a study of the different classifications of the degree of hearing loss

2017 ◽  
Vol 83 (5) ◽  
pp. 580-584 ◽  
Author(s):  
Klinger Vagner Teixeira da Costa ◽  
Sonia Maria Soares Ferreira ◽  
Pedro de Lemos Menezes
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease ◽  
Hearing Handicap

scholarly journals PREVALENCE AND PATTERNS OF HEARING LOSS AMONG CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HAEMODIALYSIS

2015 ◽  
Vol 08 (02) ◽  
Author(s):  
Jishana Jamaldeen ◽  
Aneesh Basheer ◽  
Akhil Chandra Sarma ◽  
Ravichandran Kandasamy
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease

scholarly journals Hearing and Kidney: Effects of Chronic Kidney Disease on Various Auditory Parameters – Results from a Tertiary Care Hospital in India

2019 ◽  
Vol 21 (1) ◽  
pp. 31-35
Author(s):  
Deepak Jain ◽  
HK Aggarwal ◽  
Shailesh Bhatia ◽  
Jaikrit Bhutani
Keyword(s):  
Chronic Kidney Disease ◽  
Hearing Loss ◽  
Kidney Disease ◽  
Tertiary Care ◽  
Hearing Threshold ◽  
Pure Tone Audiometry ◽  
Care Hospital ◽  
Auditory Function ◽  
Auditory Evoked Response ◽  
Patient Groups

Background: An association between chronic kidney disease (CKD) and hearing loss was first described in patients with Alport syndrome. Patients with CKD develop sensorineural hearing loss with the progression of the disease. Studies using BAER as an index of auditory function among patients with CKD showed evidence of various degrees of auditory dysfunction. Materials and methods: 100 adult CKD patients (stage 3 – 5 and 5D) and 50 controls were included in the study. Clinical and biochemical parameters were assessed and all the patients and controls underwent Pure Tone Audiometry (PTA) and Brainstem Auditory Evoked Response (BAER) evaluation. Results: When hearing thresholds were compared between the patients and controls PTA showed an increase in hearing threshold in all patient groups. This increase was more noticeable at higher frequencies (4 and 8 kHz). Compared with healthy controls, a highly significant delay was observed in CKD patients in both absolute and interpeak latencies in BAER in the present study. Conclusion: The present study provides a concrete evidence to the otherwise disputed relation of auditory function in CKD proving that hearing is permanently affected by ESRD at all levels of the auditory neural pathway. J MEDICINE JAN 2020; 21 (1) : 31-35

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