Diving into cellular signalling

10.33540/622 ◽  
2021 ◽  
Author(s):  
◽  
Niels Marinus Leijten
Keyword(s):  
Cellular Signalling

scholarly journals Cellular Signalling C25-C28 PC121-PC125

2005 ◽  
Vol 567 (suppl) ◽  
pp. 14P-147P
Keyword(s):  
Cellular Signalling

Local Ca2+ Signals in Cellular Signalling

2004 ◽  
Vol 4 (3) ◽  
pp. 263-275 ◽  
Author(s):  
N. Macrez ◽  
J. Mironneau
Keyword(s):  
Cellular Signalling

scholarly journals When nutrition interacts with osteoblast function: molecular mechanisms of polyphenols

2009 ◽  
Vol 22 (1) ◽  
pp. 68-81 ◽  
Author(s):  
Anna Trzeciakiewicz ◽  
Véronique Habauzit ◽  
Marie-Noëlle Horcajada
Keyword(s):  
Bone Health ◽  
Molecular Mechanisms ◽  
Vegetable Intake ◽  
Cell Metabolism ◽  
Bone Cell ◽  
Mitogen Activated Protein Kinase ◽  
Present Review ◽  
Activator Protein 1 ◽  
Cellular Signalling ◽  
Osteoblast Function

Recent research has provided insights into dietary components that may optimise bone health and stimulate bone formation. Fruit and vegetable intake, as well as grains and other plant-derived food, have been linked to decreased risk of major chronic diseases including osteoporosis. This effect has been partially attributed to the polyphenols found in these foods. Thus, it has been suggested that these compounds may provide desirable bone health benefits through an action on bone cell metabolism. The present review will focus on how some polyphenols can modulate osteoblast function and reports which cellular signalling pathways are potentially implicated. However, to date, despite numerous investigations, few studies have provided clear evidence that phenolic compounds can act on osteoblasts. Polyphenols cited in the present review seem to be able to modulate the expression of transcription factors such as runt-related transcription factor-2 (Runx2) and Osterix, NF-κB and activator protein-1 (AP-1). It appears that polyphenols may act on cellular signalling such as mitogen-activated protein kinase (MAPK), bone morphogenetic protein (BMP), oestrogen receptor and osteoprotegerin/receptor activator of NF-κB ligand (OPG/RANKL) and thus may affect osteoblast functions. However, it is also important to take in account the possible interaction of these compounds on osteoclast metabolism to better understand the positive correlation reported between the consumption of fruit and vegetables and bone mass.

Redox modification of caveolar proteins in the cardiovascular system- role in cellular signalling and disease

2017 ◽  
Vol 109 ◽  
pp. 61-74 ◽  
Author(s):  
Kristen J. Bubb ◽  
Asa Birna Birgisdottir ◽  
Owen Tang ◽  
Thomas Hansen ◽  
Gemma A. Figtree
Keyword(s):  
Cardiovascular System ◽  
Cellular Signalling

Changes in Cellular Signalling

2015 ◽  
Vol 27 (3) ◽  
pp. A3-A4
Keyword(s):  
Cellular Signalling
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