Essential iris atrophy with secondary angle closure glaucoma: A rare spectrum of Irido-corneal endothelial syndrome

2019 ◽  
Vol 1 (2) ◽  
pp. 25-28
Author(s):  
Vallinayagam Muthukrishnan ◽  
Stephanie Sebastian ◽  
Sajeeth Kurinjhi ◽  
Senthil Prasad
Keyword(s):  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Iris Atrophy

scholarly journals Medical and surgical management has a role in control of intraocular pressure in early detected iridocorneal endothelial syndrome: case series

2017 ◽  
Vol 4 (2) ◽  
pp. 589
Author(s):  
Archana Rath ◽  
Sumita Mohapatra ◽  
Rakesh A. Betdur ◽  
Harshvardhan V. K.
Keyword(s):  
Intraocular Pressure ◽  
Mitomycin C ◽  
Clinical Presentation ◽  
Management Strategies ◽  
Case Series ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Glaucoma Medication ◽  
Iridocorneal Endothelial Syndrome ◽  
Iris Atrophy

Iridocorneal endothelial syndrome is a rare ocular disorder characterized by abnormal endothelization of angle structure and iris producing characteristic manifestation including secondary angle closure glaucoma. The purpose is to present four cases of iridocorneal endothelial syndrome with glaucoma and discuss clinical presentation and management strategies. Out of four cases, two cases of Cogan-Reese syndrome who present early have well controlled IOP with trabeculectomy with mitomycin-C. One case who presented late with progressive iris atrophy and secondary angle closure glaucoma went to absolute stage in spite of trabeculectomy with mitomycin-C. One case with Chandler’s syndrome has well controlled IOP with topical anti-glaucoma medication.

Bilateral laser peripheral iridotomy in a co-occurrence of unilateral iridocorneal endothelial syndrome and chronic angle closure glaucoma

2021 ◽  
pp. 112067212110678
Author(s):  
Navjot Singh Ahluwalia ◽  
Rakesh Shakya ◽  
Dhairya Parikh ◽  
Devindra Sood
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Specular Microscopy ◽  
Laser Peripheral Iridotomy ◽  
First Case ◽  
Peripheral Iridotomy ◽  
Iris Atrophy

Purpose To report a case of unilateral Iridocorneal endothelial (ICE) syndrome- Progressive iris atrophy (PIA) with an overlapping chronic angle closure glaucoma (CACG) and to highlight the effect of bilateral Laser peripheral iridotomy (LPI) in such a co-occurrence. Case description A patient presented to us with bilateral gradual painless progressive diminution of vision. Both eyes (BE) had a clear cornea, shallow peripheral anterior chamber depth, grade 2 nuclear sclerosis, raised intraocular pressure and glaucomatous optic neuropathy. In addition, the Left eye (LE) had an irregular anterior chamber, peripheral anterior synechiae (PAS) extending to cornea, patchy iris atrophy, subtle corectopia and a low endothelial cell count on specular microscopy. Indentation gonioscopy led to the diagnoses of CACG BE with ICE syndrome- PIA LE. LPI was performed bilaterally. On Anterior Segment Optical Coherence Tomography (ASOCT), there was evident widening of the angle away from PAS in the Right eye as well as in the LE with PIA post LPI. Conclusion This is a unique case of unilateral PIA with an associated CACG in BE. It is the first case demonstrating the effect of bilateral LPI in such a case scenario. Though not indicated in ICE syndrome, LPI did show short term evidence of significant widening of the angle away from areas of PAS even in the eye with PIA having a limited high PAS and a concurrent primary (chronic) angle closure disease.

Effect of postural changes on intraocular pressure in patients with acute angle-closure glaucoma in Indian population

2020 ◽  
Vol 3 ◽  
pp. 2
Author(s):  
Sanjay Mishra ◽  
Ashok Kumar
Keyword(s):  
Intraocular Pressure ◽  
Acute Angle ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Sitting Position ◽  
Rebound Tonometer ◽  
Antiglaucoma Medication ◽  
Primary Angle Closure Glaucoma ◽  
Postural Changes ◽  
Healthy Control

Objective: The objective of the study was to compare the posture-induced intraocular pressure (IOP) changes in primary angle-closure glaucoma (PACG) with or without glaucoma medications, and healthy control eyes with normal IOPs in Indian subjects. Materials and Methods: The IOP was measured in the sitting position and the supine position after 10, 20, and 30 min with a rebound tonometer. Results: Twenty-five patients with PACG and 30 controls with normal IOPs were studied. The IOP in the sitting position measured with the rebound tonometer was 13.8 + 3.2 mm Hg in eyes with PAC, and 12.9 + 2.9 mm Hg in eyes with normal IOPs. The IOP increased to 14.4 mm Hg, 16.8 mm Hg, and 18.9 mm Hg at 10 min, 20 min, and 30 min in PACG subjects. In normal age-matched controls, the IOP increased to 13.4 mm Hg, 14.9 mm Hg, and 17.8 mm Hg at 10 min, 20 min, and 30 min, respectively, but none of these differences were significant (P = 0.09; P = 0.08, P = 0.08). The mean postural IOP change from baseline was also not significant between the two groups. Only three patients were on single antiglaucoma medication with well-controlled IOP in the PACG group. Conclusions: Postural IOP changes are comparable among eyes with PACG with and without glaucoma medications, and control eyes.

Glaucoma at a tertiary referral eye hospital in Nepal

1970 ◽  
Vol 3 (2) ◽  
pp. 123-127
Author(s):  
I Paudyal ◽  
SS Thapa ◽  
G Paudyal ◽  
R Gurung ◽  
S Ruit
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Applanation Tonometry ◽  
Acute Angle ◽  
Secondary Glaucoma ◽  
Angle Closure Glaucoma ◽  
Field Analysis ◽  
Angle Closure ◽  
Open Angle ◽  
Tertiary Referral

Background: Glaucoma is an important cause of blindness. Objective: To report the distribution of various types of glaucoma among patients presenting to a tertiary eye hospital in Nepal. Materials and methods: All new patients visiting the hospital between March 2007 and February 2008 underwent a comprehensive eye examination. Whenever glaucoma was suspected, patients were referred to fellowship-trained glaucoma specialists. Patients received a comprehensive glaucoma workup including applanation tonometry, stereoscopic examination of the optic nerve head performed by the glaucoma specialists, and a Humphrey visual field analysis (SITA 24 - 2). Results: 447 patients were newly diagnosed with glaucoma. 171 (38.2 %) patients had primary open-angle glaucoma (POAG), while 143 (32 %) had primary angle-closure glaucoma (PACG). The average age of presentation of patients with POAG was 65.78 ± 9.1 years, while the average age for PACG patients was 54.6 ±12.8 years. 30 (21 %) patients with PACG had acute angle-closure on presentation, while 113 (79 %) had chronic angle closure glaucoma. 107 (75 %) of these patients with PACG had visual acuity of less than 3/60 (20/ 400) in the worse eye at presentation. The most common form of secondary glaucoma was lens-induced (5.3 %), followed by neovascular (3.2 %) and uveitic glaucoma (3.2 %). Conclusion: The most common glaucoma seen in a tertiary referral eye hospital of Nepal is primary open-angle glaucoma. Among the angle-closure glaucoma, chronic angle-closure is the most common. Lens-induced glaucoma is still the commonest cause of secondary glaucoma. Keywords: glaucoma, open-angle, angle-closure, lens-induced DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5263 Nepal J Ophthalmol 2011; 3(2): 123-127

scholarly journals Etiologies and clinical characteristics of young patients with angle-closure glaucoma: a 15-year single-center retrospective study

2021 ◽  
Author(s):  
Feng Gao ◽  
Jiajian Wang ◽  
Junyi Chen ◽  
Xiaolei Wang ◽  
Yuhong Chen ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Anterior Segment ◽  
Young Patients ◽  
Case Series ◽  
Neovascular Glaucoma ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Uncommon Presentation ◽  
Underlying Causes

Abstract Purpose To investigate the etiologies and the clinical characteristics of angle-closure glaucoma (ACG) patients younger than 40 years old in Chinese. Methods Inpatients with diagnosis of ACG and diagnosed age younger than or equal to 40 years old, who were admitted in Eye, Ear, Nose, and Throat Hospital Fudan University from 2002 to 2017, were included in this retrospective non-comparative case series. The underlying causes and clinical features for all the patients were analyzed by comprehensive review of medical charts. Results A total of 298 patients (463 eyes) met the criteria, including 153 females (51.3%) and 145 males (48.7%); the mean age was 25.6 ± 13.0 years. Primary angle-closure glaucoma (PACG), uveitis, and anterior segment dysgenesis (ASD) were the top three etiologies in our patients, which accounted for 32.6%, 20.3%, and 15.1% of the total patients respectively. PACG mainly occurs after 30 years of age and ASD is the top reason of ACG in patients younger than 20 years old. Other known etiologies include iridocorneal endothelial syndrome, neovascular glaucoma, nanophthalmos, retinitis pigmentosa, spherophakia, bestrophinopathy, persistent fetal vasculature, iridociliary cysts, congenital retinoschisis, Marfan’s syndrome, retinopathy of prematurity, familial exudative vitreoretinopathy, congenital retinal folds, Coat’s disease, and neurofibromatosis. Conclusions We described the uncommon presentation of ACG in Chinese young patients. Although unusual, most of the etiologies could be identified. Therefore, more careful and comprehensive examinations are needed for early detection and timely treatment for young ACG patients.

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