Evaluating and comparing the efficacy of histopathology to TVS/TAS in diagnosing the abnormal uterine bleeding: A prospective clinical study

Regular periods are necessary to maintain good health of women. Any abnormality in Rituchakra leads to excessive and irregular uterine bleeding which is known as Asrigdara which can be correlated to Abnormal Uterine bleeding. In Ayurvedic text, many preparations are described to treat Asrigdara. Samshodhan therapy is mainstay in the management of Artava related disorders of which Basti is supreme to manage Asrigdara. In conventional science, Hormonal therapy is given but chances of recurrence of the disease are high. This study was planned to provide simple, safe, non- hormonal drug for the patients of Asrigdara. Total 40 patients fulfilling the inclusion criteria were selected randomly from Dept. of Stree roga and Prasuti tantra O.P.D.and I.P.D. The total effect of drug was evaluated on the basis of signs and symptoms after completion of therapy. Overall effect of therapy shows in group-I 6 (60%) patients were markedly improved, 11 (61.11%) were partially improved and 1 (5.6%) was not improved and group II- 6 (33.33%) patients were cured, 9 (50%) were markedly improved, 2 (11.1%) were partially improved, and 1 (5.6%) was unimproved. Thus, Basti Chikitsa manifested promising results for the management of Asrigdara, although hormonal pill manifested better cycle but for shorter duration.

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Clinical study of diagnostic hysteroscopy in abnormal uterine bleeding and its histopathological correlation

IOSR Journal of Dental and Medical Sciences ◽

10.9790/0853-0534346 ◽

2013 ◽

Vol 5 (3) ◽

pp. 43-46 ◽

Cited By ~ 2

Author(s):

Dr. ChannareddySunitha Dr. ChannareddySunitha

Keyword(s):

Clinical Study ◽

Abnormal Uterine Bleeding ◽

Uterine Bleeding ◽

Histopathological Correlation ◽

Diagnostic Hysteroscopy

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Efficacy and safety of ormeloxifene in the management of dysfunctional uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20191933 ◽

2019 ◽

Vol 8 (5) ◽

pp. 1864

Author(s):

Sabah Malik ◽

Saba Musharaf ◽

Fidah Malik ◽

Mohd Abass

Keyword(s):

Blood Loss ◽

Endometrial Thickness ◽

Abnormal Uterine Bleeding ◽

Uterine Bleeding ◽

Menstrual Blood ◽

Prospective Clinical Study ◽

Efficacy And Safety ◽

Menstrual Blood Loss ◽

Dysfunctional Uterine Bleeding ◽

The Mean

Background: The term dysfunctional uterine bleeding (DUB) is used for abnormal uterine bleeding occurring in the absence of identifiable pathology. A number of drugs are available for management of DUB- nonsteroidal anti-inflammatory drugs, tranexamic acid, ethamsylate, hormones like Oral contraceptives progestins etc. The present study was done to determine the efficacy and safety of ormeloxifene in the management of DUB.Methods: This prospective clinical study involved 50 cases with DUB who were treated with ormeloxifene 60 mg tablet twice a week for first 12 weeks and the once a week for next 12 weeks. They were followed after 6 months of therapy. The outcome was studied by assessment of menstrual blood loss by PBAC score, Hb level in g/dl, endometrial thickness in mm, relief of dysmenorrheal and any side effects of drugs.Results: The median PBAC score was significantly reduced from 316 to 52 after 6 months of therapy. The mean Hb concentration was significantly increased from 7.8 g/dl to 9.1 g/dl at 6 months of therapy. The mean endometrial thickness was reduced from 10 mm to 7.9 mm after 6 months of therapy. 66% of women showed marked subjective improvement in symptoms. Amenorrhea was the main side effect (12%).Conclusions: Ormeloxifene has significant effect in reducing endometrial thickness, decreasing the amount of menstrual blood loss, reducing dysmenorrhea and thereby improving the general condition of the patient. It is definitely a better alternative to hysterectomy in women who wish to avoid surgeries and maintain their reproductive functions.

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A CLINICAL STUDY TO EVALUATE THE EFFECT OF SPHATIKAYUKTHA RASA SINDOORA WITH LODHRA KASHAYA IN DYSFUNCTIONAL UTERINE BLEEDING

International Journal of Ayurveda and Pharma Research ◽

10.47070/ijapr.v9i4.1868 ◽

2021 ◽

pp. 32-39

Author(s):

Lijima C ◽

Shahina Mole S

Keyword(s):

Clinical Study ◽

Treatment Period ◽

Drug Administration ◽

Abnormal Uterine Bleeding ◽

Work Capacity ◽

Uterine Bleeding ◽

Rank Test ◽

Dysfunctional Uterine Bleeding ◽

Signed Rank Test

Dysfunctional Uterine Bleeding is defined as a state of abnormal uterine bleeding without any clinically detectable organic, systemic and iatrogenic cause. The prevalence varies widely but an incidence of 10% amongst new patients attending the outpatient seems logical. Along with increased susceptibility to iron deficiency, heavy menstrual bleeding can negatively impact physical, emotional and social quality of life and reduce work capacity of females. Objective: A clinical study was conducted to evaluate the effect of Sphatikayuktha Rasa Sindoora with Lodhra Kashaya in Dysfunctional Uterine Bleeding. Design: This pre-post interventional study was conducted among 20 females in the age group 20-45 years who had the symptoms of Dysfunctional Uterine Bleeding for the past 3 cycles. Drug administration started on the 3rd day of menstruation and was continued till bleeding stopped or upto a maximum of 7 days for 3 consecutive cycles. Follow up was done in the next cycle. The condition of the patient after drug administration in the first, second and third months were separately compared with the condition of the patient before treatment. Outcome measures: Outcome variables were change in the amount, duration and frequency of bleeding. Results and Discussion: Results were analysed statistically using Wilcoxon signed rank test and Paired t-test. The treatment was effective in reducing the amount of bleeding during treatment period and the follow up period. It was effective in reducing the duration of bleeding during the treatment period as compared to the follow up period and in controlling the cycle interval during the treatment period.

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