Chronic renal failure (CRF) is one of the most important health problems in our population. From the early
stages of the disease progression, the activation of Vitamin D in kidney is affected, resulting in
abnormality in the regulation of calcium and phosphate homeostasis in the blood. In the present study, 30 Chronic Renal Failure
patients visiting Nephrology OPD and 30 age and sex matched volunteers were studied. Serum levels of Urea, Creatinine,
Calcium, Phosphate and Vitamin D were measured in the study participants. The data after statistical analysis showed
signicantly higher levels of Phophate and signicantly lower levels of Calcium and Vitamin D in the CRF patients in
comparison to healthy control subjects. Phosphate and Vitamin D also shows signicant correlation with serum creatinine levels
in the CRF patients. The present study conrms the abnormality in Calcium-Phosphorus metabolism as a complication of CRF in
our population, and highlights the importance of regularly measuring these parameters in CRF patients and possible need of
taking corrective measures in this regard.
Retrospective Analysis of Vitamin D Levels in Patients with Chronic Renal Failure, Obesity, and Cancer
