scholarly journals Coumarin-bisureas as potent fluorescent transmembrane anion transporters

2021 ◽  
Author(s):  
Mohamed Fares ◽  
Xin Wu ◽  
Daniel A. McNaughton ◽  
Alexander M. Gilchrist ◽  
William Lewis ◽  
...  
Keyword(s):  
Transport Properties ◽  
Lipid Bilayer ◽  
Anion Transport ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Anion Transporters

A series of fluorescent coumarin bis-ureas have been synthesised and their anion transport properties studied. The compounds function as highly potent HCl co-transport agents in lipid bilayer membranes.

scholarly journals Reversible Photo-Control over Transmembrane Anion Transport Using Visible-Light Responsive Supramolecular Carriers

2020 ◽  
Author(s):  
Aidan Kerckhoffs ◽  
Matthew Langton
Keyword(s):  
Visible Light ◽  
Lipid Bilayer ◽  
Bilayer Membrane ◽  
Anion Transport ◽  
Temporal Control ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Spatio Temporal ◽  
Visible Wavelengths ◽  
External Signals

<p>Ion transport across lipid bilayer membranes in biology is controlled by membrane proteins, which in turn are regulated in response to chemical-, physical- and photo-stimuli. The design of synthetic supramolecular ion transporters able to be precisely controlled by external signals, in particular bio-compatible wavelengths of visible light, is key for achieving spatio-temporal control over function. Here we report two-colour responsive molecular photo-switches that act as supramolecular transmembrane anion carriers. Reversible switching of the photo-switch within the lipid bilayer membrane is achieved using biocompatible visible wavelengths of light, such that temporal control over transmembrane anion transport is achieved through alternating irradiation with red and blue light. </p>

scholarly journals Transmembrane anion transport mediated by halogen bonding and hydrogen bonding triazole anionophores

2020 ◽  
Vol 11 (18) ◽  
pp. 4722-4729 ◽  
Author(s):  
Laura E. Bickerton ◽  
Alistair J. Sterling ◽  
Paul D. Beer ◽  
Fernanda Duarte ◽  
Matthew J. Langton
Keyword(s):  
Hydrogen Bonding ◽  
Lipid Bilayer ◽  
Halogen Bonding ◽  
Anion Transport ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Triazole Derivatives ◽  
Anion Selectivity

Halogen and hydrogen bonding 1,2,3-triazole derivatives efficiently mediate anion transport across lipid bilayer membranes with unusual anion selectivity profiles.

scholarly journals Reversible Photo-Control over Transmembrane Anion Transport Using Visible-Light Responsive Supramolecular Carriers

2020 ◽  
Author(s):  
Aidan Kerckhoffs ◽  
Matthew Langton
Keyword(s):  
Visible Light ◽  
Lipid Bilayer ◽  
Bilayer Membrane ◽  
Anion Transport ◽  
Temporal Control ◽  
Lipid Bilayer Membranes ◽  
Bilayer Membranes ◽  
Spatio Temporal ◽  
Visible Wavelengths ◽  
External Signals

<p>Ion transport across lipid bilayer membranes in biology is controlled by membrane proteins, which in turn are regulated in response to chemical-, physical- and photo-stimuli. The design of synthetic supramolecular ion transporters able to be precisely controlled by external signals, in particular bio-compatible wavelengths of visible light, is key for achieving spatio-temporal control over function. Here we report two-colour responsive molecular photo-switches that act as supramolecular transmembrane anion carriers. Reversible switching of the photo-switch within the lipid bilayer membrane is achieved using biocompatible visible wavelengths of light, such that temporal control over transmembrane anion transport is achieved through alternating irradiation with red and blue light. </p>

Sign in / Sign up

Export Citation Format

Share Document