scholarly journals Clinical, Dermoscopic and Histhopatological Findings in Diagnosis of Nevus Spilus

2020 ◽  
Vol 3 (1) ◽  
pp. 60-66
Author(s):  
Amillia Risa ◽  
Ennesta Asri ◽  
Irdawaty Izrul ◽  
Alimudin Tofrizal

Introduction: Nevus spilus (NS) are seen in 0.2% to 2.3% of the population and have 0,13% to 0,2% risk for malignant transformation. Clinical, dermoscopic, and histhopatological features were describe in this case report in order to be easily recognize NS. Although NS is a benign cutaneous anomaly it has potential malignant transformation and requires regular follow up. Case Report: A case of nevus spilus in 23 years-old female was reported. There were multiple asymptomatic brownish pigmented spots over brownish patch on left cheek which gradually increased in number and size since 1 year ago. Dermatologic state: brown macules and dark brown papules in a speckled, overlying background café au lait macule. Dermoscopy revealed reticular pattern in background light brown and dark reticuloglobular pattern in dark speckled. Histopathology showed elongation of rete ridges with grouping of melanocyte cells at the tip, and proliferation of nevus cells. Conclution: Patient was planned to treat with Nd-Yag laser.

2018 ◽  
Vol 7 (4) ◽  
pp. 1-5
Author(s):  
Przemysław Krawczyk ◽  
Daniel Majszyk ◽  
Antoni Bruzgielewicz ◽  
Kazimierz Niemczyk

Granular cell tumor is benign neoplasm rarely diagnosed among young children and adolescents. The tumor developed commonly within mucous membrane of upper airways, but precise etiology is not known. Treatment is based on surgical resection of tumor and intense follow up due to risk of recurrence and malignant transformation.


2012 ◽  
Vol 87 (3) ◽  
pp. 489-490 ◽  
Author(s):  
Sheila Viana Castelo Branco Gonçalves ◽  
Neusa Yuriko Sakai Valente ◽  
José Vitor de Oliveira Junior ◽  
Daniele Loureiro Mangueira Paiva

Porokeratosis is a primary keratinizing disorder of unknown etiology. This disorder is characterized by the presence of centrifugally enlarging hyperkeratotic plaques, associated with the histopathological hallmark of cornoid lamellae. Genital porokeratosis is extremely rare. No more than thirty cases have been reported in the literature, including only one case of linear porokeratosis confined to the genital area. This case report describes a patient with genital linear porokeratosis, who was successfully treated with cryotherapy. Over two years of follow-up, the lesion improved and there was no evidence of recurrence or signs of malignant transformation. Nevertheless, there is a need for long-term follow-up data on recurrence and malignant transformation.


2021 ◽  
pp. 98-102
Author(s):  
Meina Missak ◽  
Aaron Haig ◽  
Manal Gabril

Pilomatrixoma is an uncommon, benign tumor with differentiation towards both the hair matrix and cells arising in the cortex, most frequently appearing in the first or second decade of life. In rare instances, pilomatrixomas can show malignant transformation. Pilomatrix carcinoma is extremely uncommon and has traditionally been considered a tumor of low malignant potential; however, a high local recurrence rate has been reported. There is a paucity of literature on these lesions, with only a few reports describing the spectrum of malignant changes seen in these lesions. In this case report, we present a case of pilomatrixoma in an adult patient showing atypical features. While the tumor is small, there are focal features that suggest progression to malignancy, but do not fulfill the criteria for pilomatrix carcinoma. These focal atypical features include a focal infiltrative pattern at the periphery, with a variable cytological atypia and an increased mitotic rate, up to five mitotic events/high-power field. Irregular foci of central necrosis (comedonecrosis) were present in several lobules. Some of the features identified were similar to a subset of pilomatrixoma, known as “proliferating pilomatrixoma.” However, our case did not have the diffuse changes or larger size that has been frequently reported in “proliferating pilomatrixoma.” In conclusion, given the lack of focality of the changes, the lesion in our case is best described as a pilomatricoma with atypical features. Furthermore, our case may highlight the need to ensure close clinical follow-up for these lesions with unexpected atypical features that raise concern of recurrence and malignant transformation.


2020 ◽  
Vol 8 ◽  
Author(s):  
Lamiae Hallab ◽  
Bouchra Taleb

Erysipelas is a superficial cutaneous process that is usually restricted to the dermis, but with prominent lymphatic involvement commonly caused by streptococci. We present a patient who was admitted for swelling and erythema of his left cheek. We diagnosed facial erysipelas, the curative treatment was based on the prescription of effective antibiotic therapy against streptococci and bacteria producing β-lactamase (staphylococci). Removal of the remaining teeth was scheduled during medical treatment. At a 4-month follow-up after dental removal, there has been no recurrence of erysipelas.Through a clinical case of facial erysipelas, this work allows illustrating the specificities of this pathology.


2021 ◽  
Author(s):  
Meitao Xu ◽  
Jiajia Wang ◽  
Xi Zhang ◽  
xuquan wang

Abstract Background: Fibrous dysplasia and Simple bone cyst are all common benign lesions. A case of osteosarcoma developing from fibrous dysplasia in combination with unicameral bone cyst will be discussed. The radiologic, histologic characteristics and clinical prognostic of the patient will be described. As far as we know, this is the first case report of malignant transformation secondary to fibrous dysplasia in combination with unicameral bone cyst, which is extremely rare and worthy of clinical attention or vigilance. Case presentation: This study describes a case of a 20-years-old male who suffered a 7-years history of intermittent pain in his right proximal tibia, obvious after activity and progressively worsening. Clinical symptoms and imaging examination were consistent with the characteristics of benign primary bone tumor. He underwent a successful curettage operation. Pathological diagnosis was fibrous dysplasia in combination with unicameral bone cyst. After the curettage surgery, the pain in his right knee quickly disappeared and function activities returned to normal during a regular follow-up postoperative. However, He was diagnosed with a recurrence of fibrous dysplasia in combination with unicameral bone cyst and osteosarcoma malignant transformation by chief complaint symptoms of pain and swelling in the right proximal tibia, adequate imaging examination, and pathological diagnosis at 2 years follow-up. Then the patient undergo a limb salvage with tumor prosthesis reconstruction of the right knee. Unfortunately, multiple and unresectable lymph nodes distant metastases happened even with two weeks localized inguinal radiotherapy treatment and one course of neoadjuvant chemotherapy monthly. He eventually received cancer hospice care and died eight months after the diagnosis as malignant transformation and systemic multiple organ metastasis.Conclusions: Although malignant transformation of fibrous dysplasia in combination with unicameral bone cyst is very rare, patients with this disease should be monitored and received lifelong follow-up to obtain early detection, diagnosis and treatment to maximize the efficacy of treatment and survival time. The histological and immunohistochemical findings is very important but not enough. Further research is required to clarify the pathogenesis and prevent malignant transformation.


2019 ◽  
Vol 17 (6) ◽  
pp. 835-837 ◽  
Author(s):  
Daniele Ferraro ◽  
Giovanni Battista Levi Sandri ◽  
Giovanni Vennarecci ◽  
Roberto Santoro ◽  
Marco Colasanti ◽  
...  

2017 ◽  
Vol 6 (1) ◽  
pp. 58-60 ◽  
Author(s):  
Alberto Goldman ◽  
Torello Lotti ◽  
Georgi Tchernev ◽  
Uwe Wollina

BACKGROUND: Facial reticular blue veins are of esthetic concern. Most often these veins develop on the lower lids. The safest and most effective way of treatment is by vascular lasers.CASE REPORT: We report on a successful reticular vein treatment using a long-pulsed 1064 nm Nd: YAG laser. We present a follow-up of 8 years with constant esthetic improvement without unwanted adverse events.CONCLUSION: There was no relapse demonstrating the efficacy of Nd: YAG laser.


2011 ◽  
Vol 21 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Farzan Irani ◽  
Rodney Gabel

This case report describes the positive outcome of a therapeutic intervention that integrated an intensive, residential component with follow-up telepractice for a 21 year old male who stutters. This therapy utilized an eclectic approach to intensive therapy in conjunction with a 12-month follow-up via video telepractice. The results indicated that the client benefited from the program as demonstrated by a reduction in percent stuttered syllables, a reduction in stuttering severity, and a change in attitudes and feelings related to stuttering and speaking.


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